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Downes

John Anthony Downes, Raby Mere Wirral GB

Patent application numberDescriptionPublished
20110248490SPRAY PREVENTION DEVICE - A device for preventing spray from emerging from the wheels of vehicles comprises a panel (10-13-2011

Melissa V. Downes, North Sydney AU

Patent application numberDescriptionPublished
20090326691Programmable sound player - The present invention relates generally to a programmable sound player comprising a body member, which for a substantial part is of roughly spherical ellipsoid shape; a base member joined to the body member, for resting on a planar surface; a plurality of function buttons disposed on a bottom surface of the base member, wherein each function button is adapted to be illuminated by a light source under the function buttons; wherein one of the function buttons is configured to activate a sound playing mode and a sound recording mode.12-31-2009

Paul Downes, Newport GB

Patent application numberDescriptionPublished
20110210262APPARATUS AND METHOD FOR DETECTING HIGH-ENERGY RADIATION - An apparatus for spatially correcting an image frame is disclosed. In some embodiments, the apparatus stores a frame of pixel values and scans a multi-pixel correction window across the frame. Spatial correction is performed on pixels within the window at correction positions during the scan. The spatial correction comprises estimating pixel values at value estimation positions based on one or more pixel values within the window for pixels satisfying a logical condition. The value estimation positions correspond to pixel values which do not fall within the window again during the scan. Further disclosed is an apparatus for detecting high-energy radiation, in which integration circuitry is used for integrating charge responsive to radiation photon interaction events. The circuits are controllable in accordance with an exposure control signal to vary an exposure window duration according to an operating parameter of the apparatus.09-01-2011

Peter Downes, Dundee GB

Patent application numberDescriptionPublished
20100047823Polypeptides - The use of polypeptides capable of binding to PtdIns(3,4)P02-25-2010

Sandra Downes, Manchester GB

Patent application numberDescriptionPublished
20110238178TISSUE REPAIR SCAFFOLD - The present invention provides a tissue repair scaffold comprising a secondary fibre bundle, the secondary fibre bundle comprising a plurality of primary fibre bundles, each primary fibre bundle comprising a plurality of fibres, wherein the fibres comprise a biocompatible polymer. In embodiments the biocompatible polymer is polycaprolactone (PCL) (also known as poly-ε-caprolactone) and the average diameter of the fibres is less than 1 μm. The scaffold is particularly adapted for tendon repair. In vivo mouse studies demonstrate that tendon repair can be achieved with normal ambulation returning after 24-48 hours. The scaffolds were easy to handle during surgery, being non-slippery and easy to suture in place.09-29-2011
20110245852MEDICAL DEVICE - The present invention provides a peripheral nerve growth conduit for peripheral nerve repair, in particular conduits through which peripheral nerves can grow. The conduit includes poly-ε-caprolactone (PCL). Preferably, the inner (luminal) surface of the conduit comprises pits having a depth of 1-4 μm. Suitably, the conduit may also include poly-lactic acid (PLA). The inner surface of the conduit may have been treated with an alkaline composition. The present invention also provides a method for treating a peripheral nerve damage using a peripheral nerve growth conduit including poly-ε-caprolactone (PCL). The present invention also provides a kit for treating a peripheral nerve damage having a peripheral nerve growth conduit including poly-ε-caprolactone (PCL).10-06-2011

Stephen Downes, Coleraine GB

Patent application numberDescriptionPublished
20100305082Use of FKBPL gene to identify a cause of infertility - Fertility problems affect (1 in 10) couples in Western society, making it one of the most common serious health issues. Despite this, little is known about the causes of infertility, and thus patient counseling and treatment are suboptimal. With infertility being such a common problem, identification of any cause would impact on a large number of patients, allowing better counseling, clearer diagnoses and the possibility of making more informed choices (e.g. adoption vs. IVF treatment). The present invention provides methods to identify a cause of infertility in a subject based on the genotype of the subject, in particular, by evaluating the status of the gene encoding FK506 binding protein-like (FKBPL). In particular, the present invention relates to use of the status of the gene encoding FK506 binding protein-like for identification of a cause of an infertile phenotype in a subject. Also provided, are methods method for identifying an infertile phenotype in a subject, and identifying a cause of an infertile phenotype in a subject. This diagnostic tool finds wide clinical utility in the identification of a cause of infertility, resultantly impacting on a large number of patients. Further aspects of the present invention relate to the targeting of FKBPL in order to temporarily and reversibly induce infertility in a subject. Such aspects of the present invention find utility in the development of a male contraceptive pill. Moreover, due to the high degree of homology between the human and mouse FKBPL gene, FKBPL can be targeted in order to induce infertility in mice (or other species) as a form of pest control or animal husbandry.12-02-2010

Thomas Downes, London GB

Patent application numberDescriptionPublished
20100240308DIGITAL VOICE MESSAGE SYSTEM - A digital voice message system for large retail stores and supermarkets including a terminal at the point of sale comprising a touch screen (09-23-2010
20100250374KITCHEN MANAGEMENT SYSTEM - A voice message system for use in kitchen management, particularly drive-thru restaurants, including a data processor (09-30-2010

Warren Downes, Theresa Park AU

Patent application numberDescriptionPublished
20090100556Syzygium smithii plant named 'DOW30' - ‘DOW30’ is a distinctive variety of 04-16-2009