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Dorin Panescu, San Jose US

Dorin Panescu, San Jose, CA US

Patent application numberDescriptionPublished
20080262361SYSTEM AND METHOD FOR CALIBRATING CARDIAC PRESSURE MEASUREMENTS DERIVED FROM SIGNALS DETECTED BY AN IMPLANTABLE MEDICAL DEVICE - Various techniques are provided for calibrating and estimating left atrial pressure (LAP) using an implantable medical device, based on impedance, admittance or conductance parameters measured within a patient. In one example, default conversion factors are exploited for converting the measured parameters to estimates of LAP. The default conversion factors are derived from populations of patients. In another example, a correlation between individual conversion factors is exploited to allow for more efficient calibration. In yet another example, differences in thoracic fluid states are exploited during calibration. In still yet another example, a multiple stage calibration procedure is described, wherein both invasive and noninvasive calibration techniques are exploited. In a still further example, a therapy control procedure is provided, which exploits day time and night time impedance/admittance measurements.10-23-2008
20090018597System and Method for Estimating Cardiac Pressure Based on Cardiac Electrical Conduction Delays Using an Implantable Medical Device - Techniques are provided for estimating left atrial pressure (LAP) or other cardiac performance parameters based on measured conduction delays. In particular, LAP is estimated based interventricular conduction delays. Predetermined conversion factors stored within the device are used to convert the various the conduction delays into LAP values or other appropriate cardiac performance parameters. The conversion factors may be, for example, slope and baseline values derived during an initial calibration procedure performed by an external system, such as an external programmer. In some examples, the slope and baseline values may be periodically re-calibrated by the implantable device itself. Techniques are also described for adaptively adjusting pacing parameters based on estimated LAP or other cardiac performance parameters. Still further, techniques are described for estimating conduction delays based on impedance or admittance values and for tracking heart failure therefrom.01-15-2009
20090287267System and Method for Estimating Cardiac Pressure Based on Cardiac Electrical Conduction Delays Using an Implantable Medical Device - Techniques are provided for estimating left atrial pressure (LAP) or other cardiac performance parameters based on measured conduction delays. In particular, LAP is estimated based interventricular conduction delays. Predetermined conversion factors stored within the device are used to convert the various the conduction delays into LAP values or other appropriate cardiac performance parameters. The conversion factors may be, for example, slope and baseline values derived during an initial calibration procedure performed by an external system, such as an external programmer. In some examples, the slope and baseline values may be periodically re-calibrated by the implantable device itself. Techniques are also described for adaptively adjusting pacing parameters based on estimated LAP or other cardiac performance parameters. Still further, techniques are described for estimating conduction delays based on impedance or admittance values and for tracking heart failure therefrom.11-19-2009
20090299211SYSTEM AND METHOD FOR ESTIMATING ELECTRICAL CONDUCTION DELAYS FROM IMMITTANCE VALUES MEASURED USING AN IMPLANTABLE MEDICAL DEVICE - Techniques are provided for estimating electrical conduction delays with the heart of a patient based on measured immittance values. In one example, impedance or admittance values are measured within the heart of a patient by a pacemaker or other implantable medical device, then used by the device to estimate cardiac electrical conduction delays. A first set of predetermined conversion factors may be used to convert the measured immittance values into conduction delay values. In some examples, the device then uses the estimated conduction delay values to estimate LAP or other cardiac pressure values. A second set of predetermined conversion factors may be used to convert the estimated conduction delays into pressure values. Techniques are also described for adaptively adjusting pacing parameters based on estimated LAP.12-03-2009
20100004712SYSTEMS AND METHODS FOR USE BY AN IMPLANTABLE MEDICAL DEVICE FOR DETECTING HEART FAILURE BASED ON THE INDEPENDENT INFORMATION CONTENT OF IMMITANCE VECTORS - Techniques are provided for detecting heart failure or other medical conditions within a patient using an implantable medical device, such as pacemaker or implantable cardioverter/defibrillator, or external system. In one example, physiological signals, such as immittance-based signals, are sensed within the patient along a plurality of different vectors, and the amount of independent informational content among the physiological signals of the different vectors is determined. Heart failure is then detected by the implantable device based on a significant increase in the amount of independent informational content among the physiological signals. In response, therapy may be controlled, diagnostic information stored, and/or warning signals generated. In other examples, at least some of these functions are performed by an external system.01-07-2010
20100023085ADAPTABLE COMMUNICATION SENSITIVITY FOR AN IMPLANTABLE MEDICAL DEVICE - A wireless communication threshold for an implantable medical device is automatically adapted in an attempt to maintain optimum signal detection sensitivity. In some aspects, a threshold level may be adapted to account for current environmental conditions, implant conditions, device conditions, or other conditions that may affect the reception of wireless signals at the device. In some aspects, the determination of an optimum level for the threshold involves a tradeoff relating to effectively detecting target signals while avoiding detection of noise and/or interference. In some aspects, adaptation of a threshold may be based on maximum energy levels associated with one or more sets of RF energy sample data. In some aspects, adaptation of a threshold may be based on the number of false wakeups that occur during a period of time.01-28-2010
20100030294IMPLANTABLE CARDIAC DEVICE WITH SATELLITE REFRESH - In one embodiment an implantable cardiac device is provided that includes an implantable cardiac stimulation device with an implantable satellite device coupled to it. The implantable satellite device has a charge storage device. The implantable stimulation device having a refresh generator configured to generate a charge and voltage balanced multi-phasic refresh signal with a duration less than a capacitive time constant of an electro-electrolyte interface of the implantable cardiac device and transmit the charge and voltage balanced multi-phasic refresh signal to the implantable satellite device for charging the charge storage device. In various embodiments, the charge and voltage balanced multi-phasic refresh signal having alternating phase signs and null durations between the alternating phases. In some embodiments, the refresh generator is configured to modulate the multi-phasic waveform refresh signal. The multi-phasic waveform refresh signal may be modulated to contain configuration information, status information, or other information.02-04-2010
20110028821Electrocardiographic Monitoring System and Method Using Orthogonal Electrode Pattern - A system for monitoring a cardiac condition of a patient includes a diagnostic center configured to construct a 12-lead ECG of a patient using a special ECG signals numbering less than twelve by combining the special ECG signals with a transformation matrix, and a wearable device configured to generate the special ECG signals and including. The wearable device includes a belt having one or more belt electrodes, a waistband having one or more waistband electrodes, the belt and waistband electrodes configured to contact the skin of the patient and obtain electrical signals therefrom, and a host unit in electrical communication with the belt and waistband electrodes, the host unit including circuitry for generating the special ECG signals from one or more of the acquired electrical signals and circuitry for special ECG signals to a location remote from the wearable device.02-03-2011
20110105928ECG Reconstruction For Atrial Activity Monitoring And Detection - A system includes a mobile unit having a plurality of electrodes, numbering less than ten, that are configured to contact a patient to obtain electrical signals therefrom, and a diagnostic center disposed remotely from the mobile unit. The mobile unit and/or the diagnostic center are configured to construct a first portion of an ECG (electrocardiogram) corresponding to a first portion of a cardiac cycle of the patient by processing information based on received electrical signals using a first set of transformation parameters corresponding to the first portion of the cardiac cycle. The first portion may correspond to atrial or ventricular activity.05-05-2011
20110112413METHOD FOR AUTOMATED EKG ANALYSIS - Systems and methods for analyzing electronic cardiac signals for use in clinical diagnostics are described. System and method embodiments are configured to assist in the analysis of details of EKG signals and vector cardiograms to determine how patients should be categorized into specific cardiac risk categories, such as an acute coronary syndrome category. System configurations may comprise memory devices, computing systems, and EKG data sources positioned at various local or remote positions, and connected via various data connectivity modalities. Various parameters may be utilized to assist in the drawing of one or more conclusions regarding the cardiac condition of a patient.05-12-2011
20110112414SYSTEM FOR AUTOMATED EKG ANALYSIS - Systems and methods for analyzing electronic cardiac signals for use in clinical diagnostics are described. System and method embodiments are configured to assist in the analysis of details of EKG signals and vector cardiograms to determine how patients should be categorized into specific cardiac risk categories, such as an acute coronary syndrome category. System configurations may comprise memory devices, computing systems, and EKG data sources positioned at various local or remote positions, and connected via various data connectivity modalities. Various parameters may be utilized to assist in the drawing of one or more conclusions regarding the cardiac condition of a patient.05-12-2011
20110112415SYSTEM AND METHOD FOR AUTOMATED EKG ANALYSIS - Systems and methods for analyzing electronic cardiac signals for use in clinical diagnostics are described. Parameters pertinent to a first cardiac condition of a patient, such as determining an orientation of a vector related to the cardiac activity of said patient, and comparing the vector orientation relative to a centerpoint of a population distribution representative of a second cardiac condition, may be utilized. The second cardiac condition may be selected from the group consisting of benign early repolarization, left ventricular hypertrophy, and right bundle branch block. System and method embodiments are configured to assist in the analysis of details of EKG signals and vector cardiograms to determine how patients should be categorized into specific cardiac risk categories, such as an acute coronary syndrome category.05-12-2011
20110166472IMPLANTABLE MEDICAL DEVICE AND METHOD FOR SUCH A DEVICE FOR PREDICTING HF STATUS OF A PATIENT - In an implantable medical device, such as a pacemaker or a cardioverter/defibrillator, and a method for operating such an implantable medical device, heart conditions, such as heart failure, are detected and predicted at an early stage within a patient in whom the medical device is implanted, by monitoring a patient status, for example, HF status, and predicting a worsening of the HF status of the patient and determining a patient status index, wherein a first average and a second average is compared at predetermined sample points of time. A patient status is determined based on this patient status index, wherein a patient status index that has increased substantially monotonously during a first monitoring period is determined to be an indication of an exacerbation of patient status, and in particular, a worsening of heart failure.07-07-2011

Patent applications by Dorin Panescu, San Jose, CA US