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Dorgan
Colin Richard Dorgan, Oxfordshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20110195932 | Drug Combinations for the Treatment of Duchenne Muscular Dystrophy - Combinations comprising (or consisting essentially of) one or more compounds of formula (1) with one or more ancillary agents, to processes for preparing the combinations, and to various therapeutic uses of the combinations. Also provided are pharmaceutical compositions containing the combinations as well as a method of treatment of Duchenne muscular dystrophy, Becker muscular dystrophy or cachexia using the combinations. | 08-11-2011 |
Colin Richard Dorgan, Abingdon GB
| Patent application number | Description | Published |
|---|---|---|
| 20100035956 | Compounds Having CRTH2 Antagonist Activity - Compounds of general formula (I) wherein R is phenyl optionally substituted with one or more halo substituents; and their pharmaceutically acceptable salts, hydrates, solvates, complexes or prodrugs are useful in orally administrable compositions for the treatment of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis. | 02-11-2010 |
| 20100048660 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY - There are disclosed compound of Formula (I) or (II) wherein A | 02-25-2010 |
| 20100168072 | Drug Combinations for the Treatment of Duchenne Muscular Dystrophy - Combinations comprising (or consisting essentially of) one or more compounds of the formula (I) or (II) with one or more ancillary compounds, to processes for preparing the combinations, and to various therapeutic uses of the combinations. Also provided are pharmaceutical compositions containing the combinations as well as a method of treatment of Duchenne muscular dystrophy, Becker muscular dystrophy or cachexia using the combinations. | 07-01-2010 |
| 20110195929 | COMPOUNDS FOR THE TREATMENT OF FLAVIVIRAL INFECTIONS - Described are various compounds and methods for the treatment of flaviviral infections. In particular, alkaloids and imino sugars in arabinose and/or lyxose stereochemical configuration with antiflaviviral activity are described. | 08-11-2011 |
Colin Richard Dorgan, Oxon GB
| Patent application number | Description | Published |
|---|---|---|
| 20090192195 | Compounds Having CRTH2 Antagonist Activity - Compounds of general formula (I) | 07-30-2009 |
Colin Richard Dorgan, Oxford GB
| Patent application number | Description | Published |
|---|---|---|
| 20090075938 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY - There are disclosed compound of Formula (1): A | 03-19-2009 |
John R. Dorgan, Golden, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20080254209 | POLYMER ICE AND METHODS OF MAKING AND USING THE SAME - The development provides polymer compositions that may restrict mobility of moving people, animals and objects within an area, including individual combatants and vehicles. The polymer-based compositions create an artificial ice material to directedly and reversibly reduce ground traction. The development also may include a non-toxic reversal agent, matched to the chemical characteristics of the polymer compositions, that restores traction when applied to a surface coated with the initial, traction-reducing polymer. | 10-16-2008 |
| 20090292046 | HIGH MODULUS POLYMER COMPOSITES AND METHODS OF MAKING THE SAME - The invention provides methods of producing composite polymers by combining fillers with polymers in the presence of pre-formed high molecular weight polymer. Monomer polymerization can be initiated through the addition of initiators or by reactive chemical groups on the surface of the fibers. The composite materials formed possess superior mechanical properties compared to similar polymer composites made by either purely mechanical mixing or solely polymerization of monomers in the presence of the fillers. | 11-26-2009 |
Kathleen Dorgan, Pullman, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20100291605 | ASSAYS FOR S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASES - Disclosed are novel methyltransferase assay methods, comprising: including, in a reaction mixture for a methyltransferase activity, a purified or recombinant adenosine nucleosidase activity that catalyses release of an adenine or adenine derivative moiety from a transmethylation product, and a purified or recombinant adenine deaminase activity that catalyses deamination of the released moiety to hypoxanthine or respective derivative and ammonia, wherein the methyltransferase activity is rate-limiting; and determining the methyltransferase activity by spectrophotometric or chromatographic monitoring of the coupled deamination reaction products, or of subsequent enzymatic or chemical reactions coupled thereto. Coupled oxidation of the hypoxanthine to uric acid and hydrogen peroxide is optionally affected using purified or recombinant xanthine oxidase, wherein the methyltransferase activity is rate-limiting, and wherein determining the methyltransferase activity comprises monitoring of the coupled oxidation reaction. Variations are disclosed comprises monitoring of reaction products (e.g., to detect NH3, Hypoxanthine, H2O2, and Uric Acid). | 11-18-2010 |
Roderick John Jeremiah Dorgan, Sandwich GB
| Patent application number | Description | Published |
|---|---|---|
| 20100105649 | VETERINARY COMPOSITIONS FOR TREATING MASTITIS - The present invention relates to a veterinary composition for the prophylaxis and treatment of mastitis in mammals, preferably cows. The formulations of the present invention comprise two parts that are optionally administered to the animal as a blended formulation or two separate formulations. The first part is a seal formulation comprising a gel base and a non-toxic heavy metal salt in the base. The second part of the formulation is an oil-based product preferably containing an antibiotic in an oil-based formulation. The oil-based formulation may also optionally contain any other pharmaceutically active agent for the treatment or prophylaxis of disease in cattle. | 04-29-2010 |
Stephen E. Dorgan, Hoffman Estates, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20080201910 | Apparatus And Method For Holding Garments - An improved apparatus and method for holding garments, such as neckties, is disclosed. The device comprises a magnet, preferably made of a rare Earth material and magnetized to about Grade N35 or better, and a faceplate. In one embodiment, the magnet is positioned under at least a portion of the wearer's shirt while the faceplate is positioned on a portion of the wearer's necktie. The shirt and/or necktie may additionally include pockets for housing the magnet and/or faceplate. The faceplate may be decorative, and interchangeable, for prominent display in front of the necktie. Alternatively, the device may be configured to be completely hidden from view. Several means for retaining the magnet to the shirt upon separation of the garments are presented. | 08-28-2008 |