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Doran, GB
Benjamin Doran, Hertfordshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20110105422 | USE OF G-RICH OLIGONUCLEOTIDES FOR TREATING NEOPLASTIC DISEASES - The invention relates to methods of treating patients (either adult or paediatric) with tumours using G rich oligonucleotides. In embodiments of the invention, methods of treating patients with tumours using a combination of G rich oligonucleotides and a chemotherapeutic agent are provided. There are also provided pharmaceutical compositions and kits for use in the methods of the invention. | 05-05-2011 |
Benjamin Doran, London GB
| Patent application number | Description | Published |
|---|---|---|
| 20090110632 | BIOLOGICAL MATERIALS AND USES THEREOF - There is provided by the invention a modified antibody molecule which selectively binds to a specific target, the antibody molecule being modified at, at least one amino acid residue that forms part of a glycosylation site in the variable region of an unmodified parent antibody molecule, characterised in that the modified antibody is not glycosylated at the previous glycosylation site of which the amino acid modification forms part and the modified antibody exhibits a greater binding affinity for the specific target than the unmodified parent antibody molecule. There is also provided nucleotide sequences, amino acid sequences and expression vectors encoding the modified antibodies, and uses thereof. | 04-30-2009 |
Christopher John Leslie Doran, Cambridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20100110932 | NETWORK OPTIMISATION SYSTEMS - We describe a 3D computer network optimisation tool using network management data including one or more of: network device data including hardware identification data, interface data characterising one or more interfaces of a said network device, firmware identification data for a said network device, operating system identification data for a said network device; information flow data relating to information flow within the network including network device information flow load data and link bandwidth data/statistical information flow data; as well as environmental data for a network device such as temperature or power consumption data and/or physical network device location data. The tool also uses captured network data and sniffer data from communication links; and connectivity of the network devices. A three-dimensional (3D) visualisation module constructs a 3D representation of said network including 3D representations of said network devices in conjunction with a representation of said connectivity in three dimensions. | 05-06-2010 |
Emma J. Doran, Gravesend GB
| Patent application number | Description | Published |
|---|---|---|
| 20080220448 | ANTIGENIC PROTEIN CONJUGATES AND PROCESS FOR PREPARING SAME - An improved process for the preparation of antigenic protein conjugates is provided. The conjugates preferably are formed through reaction with one or more free sulfhydryl groups in the antigenic protein. The process of the present invention preferably employs a trialkylphosphine as the reducing agent and allows for reduction of disulfide bonds in the antigenic protein and conjugation with a conjugate moiety, preferably in a single reaction vessel (i.e. “in situ”) because the process optimally does not require the removal of the reducing agent before subsequent addition of the sulfhydryl reactive agent. Antigenic protein conjugates prepared by the in situ process and their use in diagnostic immunoassays are also provided. | 09-11-2008 |
Emma J. Doran, Gravesend Kent GB
| Patent application number | Description | Published |
|---|---|---|
| 20100151490 | Antigenic Protein Conjugates and Process for Preparing Same - An improved process for the preparation of antigenic protein conjugates is provided. The conjugates preferably are formed through reaction with one or more free sulfhydryl groups in the antigenic protein. The process of the present invention preferably employs a trialkylphosphine as the reducing agent and allows for reduction of disulfide bonds in the antigenic protein and conjugation with a conjugate moiety, preferably in a single reaction vessel (i.e. “in situ”) because the process optimally does not require the removal of the reducing agent before subsequent addition of the sulfhydryl reactive agent. Antigenic protein conjugates prepared by the in situ process and their use in diagnostic immunoassays are also provided. | 06-17-2010 |
James Doran, Greater Manchester GB
| Patent application number | Description | Published |
|---|---|---|
| 20120090074 | PUNCTURE INDICATING GLOVES - A surgical glove has inner and outer surfaces. At least one of the surfaces is treated with a treatment consisting of a non-ionic hydrocarbon solution with a carbon chain in the range of 8-16 and containing a hydrophilic functionality with a pH within the range 4.5-6.5. After treatment, the treated surface or surfaces are dried, the glove packaged and then irradiated. The treatment controls the initial contact angle of the surface to be less than 70 degrees, so that liquid material will spread quickly across the treated surface or surfaces, thereby ensuring that the presence of the liquid, indicative of the glove having been compromised, is visible to the wearer or other observer as quickly as possible. | 04-19-2012 |
Nicholas John Doran, Stratford-On-Avon GB
| Patent application number | Description | Published |
|---|---|---|
| 20110091204 | METHOD AND SYSTEM FOR DEPLOYING AN OPTICAL DEMODULATOR ARRANGEMENT IN A COMMUNICATIONS NETWORK - The present application describes methods and systems for use in a communications network. More specifically, a method of deploying an optical demodulator arrangement having at least one interferometer in a network that transmits an optical signal is provided. The optical signal may include one or more on-off-keyed signals and one or more DMPSK signals. In some embodiments, the DMPSK signal is a DQPSK signal. The network may include one or more of fiber spans carrying the signals. The interferometer may have a first optical path and a second optical path and a time delay is formed between the first and second optical paths. The method may involve determining a cross-talk penalty that results from cross-phase modulation between the channels, and determining a time delay value for the interferometer. The time delay value may be determined based at least in part on determined the cross-talk penalty. | 04-21-2011 |
Nicholas John Doran, Coventry GB
| Patent application number | Description | Published |
|---|---|---|
| 20090087190 | OPTICAL COMMUNICATIONS - A dispersion management system for soliton or soliton-like transmission systems comprises a length of optical fibre (L) in which a plurality of sections (l) made up of components (N, A) of opposite sign dispersions are concatenated together. The duration of the dispersion compensation phase is short in comparison with the propagation interval in the remainder of the system and that the path average dispersion is anomalous. | 04-02-2009 |
Paul Marshall Doran, St. Helier GB
| Patent application number | Description | Published |
|---|---|---|
| 20090111521 | Data Entry Systems - A data entry system includes a hand held data entry unit having a reading sensor for sensing commands and/or data, rewritable storage for storing information relating to selectable items, a controller (a microprocessor or other processing circuitry) and a display screen for displaying a user readable representation of the commands and/or stored information for a selected item, and a telecommunication interface for the telephonic transmission of information relating to a selected item or items from the storage to a remote processing center and for the telephonic information relating to selectable items from the remote processing center to the storage. Preferably a telecommunications interface is provided in the hand held unit for cellular or other wireless telephony systems. The hand held unit can be configured to combine the data entry functions with those of audio telephony. | 04-30-2009 |
| 20110246336 | DATA ENTRY SYSTEMS - A data entry system includes a hand held data entry unit having a reading sensor for sensing commands and/or data, rewritable storage for storing information relating to selectable items, a controller (a microprocessor or other processing circuitry) and a display screen for displaying a user readable representation of the commands and/or stored information for a selected item, and a telecommunication interface for the telephonic transmission of information relating to a selected item or items from the storage to a remote processing center and for the telephonic information relating to selectable items from the remote processing center to the storage. Preferably a telecommunications interface is provided in the hand held unit for cellular or other wireless telephony systems. The hand held unit can be configured to combine the data entry functions with those of audio telephony. | 10-06-2011 |
Richard J. Doran, Kent GB
| Patent application number | Description | Published |
|---|---|---|
| 20100008079 | LED INSPECTION LAMP AND LED SPOTLIGHT - An LED inspection lamp has plurality of LED sources for emitting electromagnetic radiation at different peak wavelengths for causing visible fluorescence in different leak detection dyes. A lens is associated with each LED. Radiation passing through lenses is superimposed in target area at target distance. Another LED inspection lamp has plurality of LEDs emitting electromagnetic radiation at a peak wavelength. A lens adaptor has lens housing for attachment to LED inspection lamp with a single LED for causing visible fluorescence, and a lens. Substantially all of the radiation from the LED passes through the lens and is focused in a target area at a target distance from the lenses. LED spot lights have a similar configuration. The LEDs may produce white light from distinct LEDs or from white LEDs. The light may be a flashlight or fixed spot light. | 01-14-2010 |
Simon John Doran, Guildford GB
| Patent application number | Description | Published |
|---|---|---|
| 20080277567 | Fast laser scanning optical CT apparatus - Disclosed are scanning devices which measure and quantify optical properties within an object such as the absorption of light, refractive index, light scattering, fluorescence, and phosphorescence. Through the use of two rotating plane mirrors and two paraboloid mirrors, a laser light beam is made to traverse the object to be scanned wherein the beam is always parallel to the optical axis. The invention provides an improvement over previously reported scanning devices by virtue of increased speed and resolution. Two-dimensional projections gleaned by each scan of the object are reconstructed into a three-dimensional image through the use of various computer techniques. | 11-13-2008 |
Simon John Doran, Surrey GB
| Patent application number | Description | Published |
|---|---|---|
| 20110017924 | NOVEL RADIATION DETECTOR - The invention provides a device for the detection and mapping of radiation, the device comprising a polymeric core located within an external shell material, wherein the polymeric core comprises at least one radiation sensitive component and the external sheath comprises a collimation sheath. Preferably, the polymeric core comprises a spherical core which is encased within the external shell. The external shell is preferably comprised of a metal, most preferably lead or tungsten. The invention also provides a method for the detection and mapping of radiation in a location, which comprises: (a) placing a device according to the invention in the location to be investigated; (b) allowing the device to remain in the location and be exposed to the radiation for a predetermined length of time; (c) removing the device from the location; (d) removing the polymeric core from the external shell; and (e) analysing said polymeric core by means of an optical analysis technique applying a software-based image reconstruction algorithm in order to determine the location, form and intensity of said radiation. The device and method of the invention facilitate the detection and mapping of radiation, and find particular use in mapping the location, intensity and identity of radio-logical hazards in 3 dimensions in sites such as active cells, gloveboxes, other active plants and confined spaces. Advantages over the prior art include the lack of requirement for an electrical supply, and the ability to deal with high radiation backgrounds and to be deployed in confined or restricted spaces. | 01-27-2011 |
Stephen John Doran, Long Sutton GB
| Patent application number | Description | Published |
|---|---|---|
| 20080222072 | Analysing Documents - The text of a document is received and stored, it is analysed according to predetermined rules to identify pitfalls and features of the document, and a graphic displaying the pitfalls and features is created and displayed. | 09-11-2008 |