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Doo Sung
Doo Sung Kang, Gyeonggi-Do KR
| Patent application number | Description | Published |
|---|---|---|
| 20090018339 | Process For Preparing Crystalline Form A Of Lansoprazole - The present invention relates to a process for preparing Crystalline Form A of Lansoprazole. Specifically, the present invention relates to a process for preparing highly pure Crystalline Form A of Lansoprazole in a large scale without any additional conversion step, even by using ethanol in which Crystalline Form B is easily formed. | 01-15-2009 |
Doo Sung Lee, Suwon-Si KR
| Patent application number | Description | Published |
|---|---|---|
| 20100233264 | TEMPERATURE AND pH-SENSITIVE BLOCK COPOLYMER HAVING EXCELLENT SAFTY IN VIVO AND HYDROGEL AND DRUG DELIVERY SYSTEM USING THEREOF - Disclosed herein are pH- and temperature-sensitive block copolymer with excellent safety and a method for preparing the same and a hydrogel and a drug carrier using the block copolymer. According to the present invention, the pH- and temperature-sensitive block copolymer comprises: obtained by copolymerization of: (a) polyethylene glycol-based compound (A); and (b) poly (β-amino ester)-based oligomer (B) or poly (amido amine)-based oligomer (C) or coupling of mixture (D) thereof. In order to control biodegradation rate, the block copolymer is mixed with poly (amido amine)-based oligomer instead of the poly (β-amino ester)-based oligomer and then coupling them. | 09-16-2010 |
Doo Sung Lee, Sucheon-Si KR
| Patent application number | Description | Published |
|---|---|---|
| 20090066522 | Emergency guidance lamp system for guiding to nearest exit in the event of fire - An emergency guidance lamp system for guiding to the nearest exit in the event of a fire is provided. A fire detection sensor is installed at a specific region such as ceilings or passages of tunnels or large buildings, and detects a fire occurrence and sends a corresponding detection signal. A central control unit receives the detection signal from the fire detection sensor, judges a situation on the fire occurrence based on simulation result data of various numbers of cases of fire occurrence that have been previously performed and stored in an internal memory, and sends red and green lighting control signals most suitable for each guidance lamp apparatus installed at the site. A guidance lamp apparatus is installed on the ceiling, wall surface, or bottom surface of a passage or the like of tunnels or large buildings, and has a red lighting unit and a green lighting unit provided at the body thereof. | 03-12-2009 |
Doo Sung Lee, Gyeonggi-Do KR
| Patent application number | Description | Published |
|---|---|---|
| 20080274190 | TEMPERATURE AND pH - SENSITIVE BLOCK COPOLYMER HAVING EXCELLENT GEL STRENGTH, METHOD OF PREPARING THE SAME, AND DRUG DELIVERY SYSTEM USING THE SAME - Disclosed herein is a temperature- and pH-sensitive block copolymer having excellent gel strength, including: (a) a poly(ethylene glycol)-based compound (A) or a copolymer (B) of the poly(ethylene glycol)-based compound (A) and a biodegradable polymer; and (b) a polyurethane-based oligomer (C). Further, a method of preparing a temperature and pH-sensitive block copolymer having excellent gel strength, including: (a) synthesizing a poly(ethylene glycol)-based compound (A) or a copolymer (B) of the poly(ethylene glycol)-based compound (A) and a biodegradable polymer; and (b) coupling a polyurethane-based oligomer (C) with the copolymer (B), is disclosed. Also disclosed is a polymer hydrogel type drug delivery system, including: (a) the block copolymer; and (b) a physiologically active substance which can be included in the block copolymer. | 11-06-2008 |
| 20080293827 | Temperature and Ph Sensitive Block Copolymer and Polymeric Hydrogels Using the Same - Disclosed is a block copolymer formed by coupling the following components with each other: (a) a copolymer (A) of a polyethylene glycol (PEG) type compound with a biodegradable polymer; and (b) at least one oligomer (B) selected from the group consisting of poly(β-amino ester) and poly(amido amine). A method for preparing the same block copolymer, and a polymeric hydrogel type drug composition comprising the temperature and pH-sensitive block copolymer and a physiologically active substance that can be encapsulated with the block copolymer are also disclosed. The multiblock copolymer is obtained by copolymerization of a pH-sensitive poly(β-amino ester) and/or poly(amido amine) type oligomer, a hydrophilic and temperature-sensitive polyethylene glycol type compound and a hydrophobic and biodegradable polymer. Therefore, the block copolymer can form a polymeric hydrogel structure due to its amphiphilicity resulting from the combination of a hydrophilic group and a hydrophobic group in the copolymer and ionization characteristics depending on pH variations, and thus can be used as a drug carrier for target-directed drug delivery depending on pH variations in the body. | 11-27-2008 |
Doo Sung Lee, Gwacheon Si KR
| Patent application number | Description | Published |
|---|---|---|
| 20110150978 | PH-SENSITIVE BLOCK COPOLYMER FORMING POLYIONIC COMPLEX MICELLES AND DRUG OR PROTEIN CARRIER USING THE SAME - Disclosed is a pH-sensitive block copolymer that forms polyionic complex micelles. The block copolymer is prepared by copolymerization of (a) a polyethylene glycol compound, (b) a poly(amino acid) compound, and (c) a heterocyclic alkyl amine compound having the ability to induce the formation of ionic complexes. Further disclosed is a drug or protein carrier using the block copolymer. | 06-23-2011 |