Donovan, PA
Alison L. Donovan, Quakertown, PA US
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20100120013 | PROCEDURE FOR LONG TERM CORNEAL CULTURE - A method for long-term multi-species cornea culture and preservation is provided. Excised mammalian corneas are preserved with structural integrity by filling the endothelial cavity with a plug material. Plugged corneas are sterile-cultured for more than 21 days via an air-interface culture where nutrients from a culture media are supplied to corneal tissue primarily through the plug. Plugged corneas are incubated in culture dishes with a customized media continuously in contact with the ocular sclera and corneal plug, and periodically bathing the corneal surface epithelia. An animal-alternative toxicology assay is also provided using excised porcine corneas capable of assessing ocular injury reversibility within 21 days. Further provided is a method of mammalian corneal preservation for excised human corneas extending their storage life to three to four weeks. | 05-13-2010 |
Cindy L. Donovan, Allentown, PA US
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20120282688 | REACTOR SYSTEMS - This disclosure relates to equipment utilized to manufacture chemical agents, particularly biopharmaceuticals. In some embodiments, reactor systems comprising a mobile carriage assembly; a disposable reaction container removably attached to the carriage assembly; and, a carriage holder into which the mobile carriage assembly may be removably inserted are provided. | 11-08-2012 |
Dale E. Donovan, Pittsburgh, PA US
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20090010768 | Pumping apparatus for shear-sensitive fluids - Pumping systems for pumping shear-sensitive fluids between first and second reservoirs. In various embodiments, the pumping system may include a portable platform that supports at least one diaphragm pump thereon. The diaphragm pumps are arranged for fluid communication with first and second reservoirs. Valve arrangements may be provided that enable the shear-sensitive fluid to be pumped from a first reservoir to a second reservoir. In some embodiments, the valve arrangements enable the user to reverse the flow direction to enable the fluid to be pumped back out of the second reservoir into the first reservoir if too much fluid was initially transferred into the second reservoir. Other embodiments may employ a hand activated nozzle to discharge the pumped fluid. | 01-08-2009 |
Judith C. Donovan, Levittown, PA US
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20080274502 | Bacillus Thuringiensis CryET33 and CryET34 Compositions and Uses Therefor - Disclosed are | 11-06-2008 |
Lori Donovan, Shippensburg, PA US
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20130195326 | MEDICATION STORAGE DEVICE AND METHOD - Devices, systems, and methods for monitoring and enhancing patient adherence to a prescription drug regimen are disclosed herein. In some embodiments, a medication storage device includes a plurality of dose containers, each dose container having an interior region configured to contain a medication. The medication storage device also includes an event detection system that includes a plurality of sensors. The plurality of sensors are configured to detect a change in each dose container of the plurality of dose containers. The medication storage device also includes an imaging system. The imaging system includes a plurality of image capture devices configured to capture an image of the interior region of each dose container of the plurality of dose containers. A communications module is configured to send an indication of the change detected by the event detection system and/or an image captured by the imaging device to a remote device. | 08-01-2013 |
Megan Donovan, North Wales, PA US
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20130053499 | THICKENED AQUEOUS DISPERSIONS AND COATED SUBSTRATE PROVIDED THEREFROM - An aqueous including a particulate polymer having a particle diameter of from 0.5 microns to 150 microns, the polymer including, as copolymerized units, from 0.1% to 50%, by weight based on the polymer weight, monomer having a Hansch parameter of from 2.5 to 10, the polymer having been formed in the presence of a non-formaldehyde reductant such as, for example, from 0.01% to 0.5%, by weight based on the polymer weight, isoascorbic acid; and from 0.1% to 5%, by weight based on polymer weight, thickener is provided as is a method for forming a coated substrate and the coated substrate so formed. | 02-28-2013 |
Stephen Donovan, Revere, PA US
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20090215821 | N-Substituted Azacycles - N-substituted azacycle derivative compounds represented by formula (I): | 08-27-2009 |
Stephen F. Donovan, Revere, PA US
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20090012070 | PESTICIDAL HETEROCYCLES - It has now been found that certain novel heterocyclic derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I): R Preferred are those compounds of formula (I) where R | 01-08-2009 |
20090036306 | Insecticidal Substituted Benzylamino Heterocyclic and Heteroaryl Derivatives - Certain substituted benzylamino heterocyclic and heteroaryl derivatives have provided unexpected insecticidal and acaricidal activity. These compounds are represented by formula (1): wherein R, R1, R2, R3, and R4 are fully described herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula (1), and optionally, an effective amount of at least one of an additional compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present. | 02-05-2009 |
20090209422 | Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives - Certain substituted aminoalkyl heteroaryl and heterocyclyl derivatives have provided unexpected insecticidal and acaricidal activity. These compounds are represented by formula I: wherein R, R | 08-20-2009 |
20100137385 | Insecticidal Substituted Amino Heterocyclic and Heteroaryl Derivatives - Certain substituted amino heterocyclic and heteroaryl derivatives have provided unexpected insecticidal and acaricidal activity. These compounds are represented by formula (I): wherein R, R | 06-03-2010 |
William P. Donovan, Levittown, PA US
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20080229449 | Lepidopteran-active bacillus thuringiensis delta-endotoxin polynucleotides, compositions, and methods of use - Disclosed are | 09-18-2008 |
20080274502 | Bacillus Thuringiensis CryET33 and CryET34 Compositions and Uses Therefor - Disclosed are | 11-06-2008 |
20090094714 | Coleopteran-Toxic Polypeptide Compositions And Insect-Resistant Transgenic Plants - Disclosed are novel insecticidal polypeptides, and compositions comprising these polypeptides, peptide fragments thereof, and antibodies specific therefor. Also disclosed are vectors, transformed host cells, and transgenic plants that contain nucleic acid segments that encode the disclosed δ-endotoxin polypeptides. Also disclosed are methods of identifying related polypeptides and polynucleotides, methods of making and using transgenic cells comprising these polynucleotide sequences, as well as methods for controlling an insect population, such as Colorado potato beetle, southern corn rootworm and western corn rootworm, and for conferring to a plant resistance to a target insect species. | 04-09-2009 |
20090098099 | PLANT TRANSFORMED WITH POLYNUCLEOTIDE ENCODING LEPIDOPTERAN-ACTIVE BACILLUS THURINGIENSIS DELTA-ENDOTOXIN - Disclosed are | 04-16-2009 |
20090270327 | Lepidopteran-Active Bacillus Thuringiensis Delta-Endotoxin Compositions and Methods of Use - Disclosed are | 10-29-2009 |