Patent application number | Description | Published |
20120277192 | AMINOPYRIMIDINES AS SYK INHIBITORS - The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis. | 11-01-2012 |
20140243290 | Aminopyrimidines as SYK Inhibitors - The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis. | 08-28-2014 |
20140243336 | 2-Pyridyl Carboxamide-Containing Spleen Tyrosine Kinase (SYK) Inhibitors - The invention provides certain 2-pyridyl carboxamide-containing compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein A and B are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase. | 08-28-2014 |
20140249130 | BIPYRIDYLAMINOPYRIDINES AS SYK INHIBITORS - The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, or are prodrugs thereof, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis and cancer. | 09-04-2014 |
20140303206 | 3-Pyridyl Carboxamide-Containing Spleen Tyrosine Kinase (SYK) Inhibitors - The invention provides certain 3-pyridyl carboxamide-containing compounds of the Formula (I) (I) or pharmaceutically acceptable salts thereof, wherein A and B are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase. | 10-09-2014 |
20150148327 | SUBSTITUTED PYRIDINE SPLEEN TYROSINE KINASE (SYK) INHIBITORS - The invention provides certain substituted pyridines of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R | 05-28-2015 |
20150175575 | IMIDAZOLYL ANALOGS AS SYK INHIBITORS - The present invention provides novel imidazole analogs of Formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer. | 06-25-2015 |
20150239866 | TRIAZOLYL DERIVATIVES AS SYK INHIBITORS - Provided are triazole derivatives of Formula I which are potent inhibitors of spleen tyrosine kinase and pharmaceutical composition. The triazole derivatives are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer. | 08-27-2015 |
Patent application number | Description | Published |
20100048368 | Wall-mounted home fitness training equipment - An overall fitness trainer and can be a wall mounted unit that can utilize clip resistance bands as well as other techniques. These bands generally clip on the unit and onto different handles, bars and attachments to perform exercises. The unit can have a removable/adjustable pull up bar, dip bar and seat. It also includes a spring loaded, pull pin carriage that moves freely up and down a vertical spine. This allows for easy adjustment of the carriage and allows the user to attach the bands at multiple angles, widths and levels. This in turn increases the number of exercises the user can perform on the unit. The unit also typically has an o ring that attaches through the arm of the pull up attachment as well as a ½ O-ring at the bottom of the unit again increasing the number of exercises the user can perform. The unit can be attached to the wall with lag bolts into two or more studs. Some embodiments of the invention have an adjustable swivel foot that takes the stress off of the lag bolts and also adds to the overall load capacity of the unit. The apparatus typically has an optional telescoping central vertical spine that splits in two pieces to make the unit easier to ship. The central vertical spine allows attachments to be added and removed using spring loaded pins or plunger pins. Various embodiments of the invention can have an oscillating and telescopic bench, a dip bar, a seat, a knee stabilizer and a foot rest. All of these accessories can be attached and removed to the central spine adding to the versatility and scope of exercises that can be performed. | 02-25-2010 |
20110195822 | Wall-Mounted Home Fitness Training Equipment - An overall fitness trainer and can be a wall mounted unit that can utilize clip resistance bands as well as other techniques. These bands generally clip on the unit and onto different handles, bars and attachments to perform exercises. The unit can have a removable/adjustable pull up bar, dip bar and seat. It also includes a spring loaded, pull pin carriage that moves freely up and down a vertical spine. This allows for easy adjustment of the carriage and allows the user to attach the bands at multiple angles, widths and levels. This in turn increases the number of exercises the user can perform on the unit. The unit can be attached to the wall with lag bolts into two or more studs. Various embodiments of the invention can have an oscillating and telescopic bench, a dip bar, a seat, a knee stabilizer and a foot rest. All of these accessories can be attached and removed to the central spine adding to the versatility and scope of exercises that can be performed. Accessories can also include a baseball bat handle, baseball, medicine ball, boxing gloves, football, squat belt, golf club handle, hockey stick handle, lacrosse stick handle and any other handle of any other sport unit. | 08-11-2011 |
20130212857 | Wall-Mounted Home Fitness Training Equipment - An overall fitness trainer and can be a wall mounted unit that can utilize clip resistance bands as well as other techniques. These bands generally clip on the unit and onto different handles, bars and attachments to perform exercises. The unit can have a removable/adjustable pull up bar, dip bar and seat. It also includes a spring loaded, pull pin carriage that moves freely up and down a vertical spine. This allows for easy adjustment of the carriage and allows the user to attach the bands at multiple angles, widths and levels. This in turn increases the number of exercises the user can perform on the unit. The unit can be attached to the wall with lag bolts into two or more studs. | 08-22-2013 |
20140018215 | Wall-Mounted Home Fitness Training Equipment - An overall fitness trainer and can be a wall mounted unit that can utilize clip resistance bands as well as other techniques. These bands generally clip on the unit and onto different handles, bars and attachments to perform exercises. The unit can have a removable/adjustable pull up bar, dip bar and seat. It also includes a spring loaded, pull pin carriage that moves freely up and down a vertical spine. This allows for easy adjustment of the carriage and allows the user to attach the bands at multiple angles, widths and levels. This in turn increases the number of exercises the user can perform on the unit. The unit can be attached to the wall with lag bolts into two or more studs. | 01-16-2014 |
20140031182 | Wall-Mounted Home Fitness Training Equipment - An overall fitness trainer and can be a wall mounted unit that can utilize clip resistance bands as well as other techniques. These bands generally clip on the unit and onto different handles, bars and attachments to perform exercises. The unit can have a removable/adjustable pull up bar, dip bar and seat. It also includes a spring loaded, pull pin carriage that moves freely up and down a vertical spine. This allows for easy adjustment of the carriage and allows the user to attach the bands at multiple angles, widths and levels. This in turn increases the number of exercises the user can perform on the unit. The unit can be attached to the wall with lag bolts into two or more studs. | 01-30-2014 |
Patent application number | Description | Published |
20090064492 | METHOD OF MANUFACTURING RF ABLATION PROBE WITH UNIBODY ELECTRODE ELEMENT - An ablation probe and method of manufacturing the ablation probe are provided. The probe comprises a probe shaft and a unibody electrode element. The unibody electrode element comprises a common electrode base located at the distal end of the shaft, and a plurality of electrode tines distally extending from the electrode base. The electrode element may be created by forming divisions (such as slits or slots) from a first end of an electrically conductive elongate member towards an opposing second end of the elongate member. Alternatively, the divisions can be formed from a first end of an electrically conductive sheet towards an opposing second end of the sheet, and then bent or rolled to form the elongate member. In either case, the common electrode base can either be separately mounted to a probe shaft, or the probe shaft can be formed from the elongate member, in which case, the electrode base will be integrated with the probe shaft as a unibody structure. The electrode tines can be optionally shaped, e.g., to proximally evert. | 03-12-2009 |
20100280514 | METHOD OF MANUFACTURING RF ABLATION PROBE WITH UNIBODY ELECTRODE ELEMENT - An ablation probe and method of manufacturing the ablation probe are provided. The probe comprises a probe shaft and a unibody electrode element. The unibody electrode element comprises a common electrode base located at the distal end of the shaft, and a plurality of electrode tines distally extending from the electrode base. The electrode element may be created by forming divisions (such as slits or slots) from a first end of an electrically conductive elongate member towards an opposing second end of the elongate member. Alternatively, the divisions can be formed from a first end of an electrically conductive sheet towards an opposing second end of the sheet, and then bent or rolled to form the elongate member. In either case, the common electrode base can either be separately mounted to a probe shaft, or the probe shaft can be formed from the elongate member, in which case, the electrode base will be integrated with the probe shaft as a unibody structure. The electrode tines can be optionally shaped, e.g., to proximally evert. | 11-04-2010 |
20130283607 | METHOD OF MANUFACTURING RF ABLATION PROBE WITH UNIBODY ELECTRODE ELEMENT - An ablation probe and method of manufacturing the ablation probe are provided. The probe comprises a probe shaft and a unibody electrode element. The unibody electrode element comprises a common electrode base located at the distal end of the shaft, and a plurality of electrode tines distally extending from the electrode base. The electrode element may be created by forming divisions (such as slits or slots) from a first end of an electrically conductive elongate member towards an opposing second end of the elongate member. Alternatively, the divisions can be formed from a first end of an electrically conductive sheet towards an opposing second end of the sheet, and then bent or rolled to form the elongate member. In either case, the common electrode base can either be separately mounted to a probe shaft, or the probe shaft can be formed from the elongate member, in which case, the electrode base will be integrated with the probe shaft as a unibody structure. The electrode tines can be optionally shaped, e.g., to proximally evert. | 10-31-2013 |
20140058426 | METHOD OF AND APPARATUS FOR POSITIONING AND MAINTAINING THE POSITION OF ENDOSCOPIC INSTRUMENTS - The present invention provides an apparatus for, and a method of, accurate positioning of endoscopic instruments. Accurate positioning of the instruments is accomplished through the inclusion of a steering ability within the device. After the endoscopic instrument is properly positioned, the present invention may use rapid exchange technology, soft locks, and mechanical locks to maintain the position of the endoscopic instrument. Rapid exchange technology is used to minimize displacement forces present on the guidewire or catheters. Soft locks and mechanical locks resist movements caused by displacement forces. | 02-27-2014 |
Patent application number | Description | Published |
20140217172 | APPARATUS, SYSTEM AND METHOD FOR STIMULATING AND SECURING RETAIL TRANSACTIONS - An apparatus, system and method of stimulating a retail transaction. The apparatus, system and method may include obtaining, via an opt-in to an in-store wireless network, of consumer device data regarding a plurality of consumer mobile devices, the consumer data comprising device use data, prior purchase data, and location data; receiving video surveillance data related to at least one consumer having the consumer device data; providing digital signage data to a plurality of in-store items available for purchase; interrelating, from at least one non-transitory computer-readable medium storing at least the consumer device data, the video surveillance data, and the digital signage data, of at least the consumer device data, the video surveillance data, and the digital signage data by at least one computing processor; and applying, by the computing processor, of a plurality of business rules to the interrelated datas to communicate uniquely with a one of the at least one consumers via at least the digital signage. | 08-07-2014 |
20140222630 | APPARATUS, SYSTEM AND METHOD FOR FACILITATING AND SECURING ACCESS TO TRANSACTIONS IN A RETAIL ENVIRONMENT - An apparatus, system and method of facilitating a retail transaction. The apparatus, system and method may include obtaining, via an opt-in to an in-store wireless network, of consumer device data regarding a plurality of consumer mobile devices, the consumer data comprising device use data, prior purchase data, and geo-location data; receiving video surveillance data related to at least one consumer having the consumer device data; interrelating, from at least one non-transitory computer-readable medium storing at least the consumer device data and the video surveillance data, of at least the consumer device data and the video surveillance data by at least one computing processor; and unlocking, at a direction of the computing processor and pursuant to a plurality of business rules to the interrelated datas, at least one in-store protection proximate to a location indicated by the geo-location data to allow a prospective purchasing one of the consumers to access at least one previously locked in-store item. | 08-07-2014 |
20140222680 | APPARATUS, SYSTEM AND METHOD FOR SECURE TRANSACTIONS AND MONITORING IN A RETAIL ENVIRONMENT - An apparatus, system method of providing mobile checkout. The apparatus, system and method may include obtaining, via an opt-in to an in-store wireless network, of consumer device data regarding a plurality of consumer mobile devices, the consumer data comprising device use data, prior purchase data, and GPS data, receiving video surveillance data related to at least one consumer having consumer device data, interrelating, from at least one non-transitory computer-readable medium storing at least the consumer device data and the video surveillance data, of at least the consumer device data and the video surveillance data by at least one computing processor, and applying, by the computing processor, of a plurality of business rules to the interrelated datas to enable at least the mobile checkout, wherein the mobile checkout includes a purchase of at least one in-store item via the consumer device associated with the purchasing one of the at least one consumer. | 08-07-2014 |
Patent application number | Description | Published |
20090118751 | APPARATUS AND METHOD FOR ALERTING GENERATOR FUNCTIONS IN AN ULTRASONIC SURGICAL SYSTEM - The present invention provides a system for surgery which includes an ultrasonic hand piece having a end-effector, a console having a digital signal processor (DSP) for controlling the hand piece, and a memory disposed in the end-effector. The generator console sends a drive current to drive the hand piece which imparts ultrasonic longitudinal movement to the blade. As the generator console reads the memory, the hand piece is authenticated for use with the generator console if a copyrighted data string is present in the memory. In a particular embodiment, the data string is an encrypted code, where the hand piece is authenticated for use with the console by decoding a corresponding encryption algorithm resident in the generator console and providing a responding data pattern. | 05-07-2009 |
20100125292 | ULTRASONIC SURGICAL SYSTEM - An ultrasonic surgical system utilizes a digital control system to generate ultrasonic drive current for transducers that are located in a hand piece and are attached to a surgical scalpel or blade in the hand piece so as to vibrate the blade in response to the current. The digital control includes a digital signal processor (DSP) or microprocessor; a direct digital synthesis (DDS) device; a phase detection logic scheme, a control algorithm for seeking and maintaining resonance frequency; and design scheme that allows to regulate current, voltage, and power delivered to an ultrasonic thereby a device. Such system allows the power versus load output curve to be tailored to a specific hand piece, which improves efficiency and reduces heat. Further, the components of the digital system are much less sensitive to temperature variations, thereby allowing it to operate with narrow as needed frequency range around the desired resonance in order to avoid excitation of other resonances. Also, the digital system provides increased flexibility in locating the resonance frequency of the blade and running diagnostic tests. The start of a user initiated diagnostic test that requires movement of the blade is caused by operating two of the system switches, which guards against accidental operation of the blade which could be harmful if in contact with tissue and also generate false diagnostic results. In addition, the system has interlock with an Electrosurgical unit so that it is not effected by the electromagnetic interference generated by that unit. | 05-20-2010 |
20120232422 | RESPONSE TESTING FOR CONSCIOUS SEDATION UTILIZING A NON-EAR-CANAL-CONTACTING SPEAKER - A conscious sedation system and a request assembly for a response testing apparatus for a conscious sedation system. The conscious sedation system includes a controller which generates a request for a predetermined response from a patient and which analyses at least a response made by the patient to the request to determine a level of sedation of the patient. The response testing apparatus includes a request assembly and a response assembly. The request assembly audibly communicates to the patient the request generated by the controller and includes a non-ear-canal-contacting speaker. The response assembly senses the response and communicates the response to the controller. | 09-13-2012 |