Patent application number | Description | Published |
20100185699 | SYSTEM AND METHOD FOR REPRESENTING N-LINKED GLYCAN STRUCTURES - A fixed-length alpha-numeric code for representing N-linked glycan structures commonly found in secreted glycoproteins from mammalian cell cultures. The code employs a pre-assigned alpha-numeric index to represent the monosaccharides attached in different branches to the core glycan structure. The present branch-centric representation allows visualization of the structure while the numerical nature of the code makes it machine readable. A difference operator can be defined to quantitatively differentiate between glycan structures for further analysis. The code can be incorporated in a retrievable format into an information management system. A method is also provided for representing the structure of at least a portion of an oligosaccharide, using the fixed-length alpha-numeric code. | 07-22-2010 |
20140088885 | METHOD, AN APPARATUS, AND A COMPUTER PROGRAM PRODUCT FOR IDENTIFYING METABOLITES FROM LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY MEASUREMENTS - The present invention relates to a method for identifying metabolites present in a set of samples. The method may include: (a) forming a plurality of peak-groups, wherein each peak-group comprises mass peaks representative of a specific ion in each chromatographic run; (b) forming a plurality of clusters, wherein each cluster comprises at least one peak-group of (a) each having similar chromatographic profiles; and (c) generating a list of metabolite predictions, wherein each metabolite prediction is selected from the plurality of clusters of (b). | 03-27-2014 |
20140244228 | CODON OPTIMIZATION OF A SYNTHETIC GENE(S) FOR PROTEIN EXPRESSION - The present disclosure is related to a method of optimization of a nucleotide coding sequence coding for an amino acid sequence, wherein the nucleotide coding sequence is optimized for expression in a host cell. The present disclosure also relates to system for optimizing a nucleotide coding sequence coding for an amino acid sequence, wherein the nucleotide coding sequence is optimized for expression in a host cell. | 08-28-2014 |
Patent application number | Description | Published |
20140354519 | DISPLAY APPARATUS - A display apparatus including a display module, and a drive device to deform the display module, is provided. The drive device switches the display module between a planar state and a curved state in which at least one lateral end of the display module protrudes forward. As such, the user may use the display module both in a planar state and a curved state. | 12-04-2014 |
20150145837 | DISPLY APPARATUS AND METHOD OF CONTROLLING THE SAME - Display apparatuses and methods are provided. A display apparatus includes a display module, a driving device that is configured to deform the display module from a flat surface state to a curved surface state and deform the display module from the flat surface state to the curved surface state, and a base member that is disposed at a rear of the display module and supports the driving device. | 05-28-2015 |
20150195932 | DISPLAY APPARATUS - Disclosed herein is a display apparatus including: a display module configured to be changed to a curved state, the display module comprising a first lateral edge and a second lateral edge, the first and the second lateral edges protruding forward in the curved state; a base frame disposed behind the display module; a shield member rotatably connected to lateral ends in a widthwise direction of the display module; and a cover unit having a first end connected to the shield member and a second end opposite from the first end connected to the base frame and configured to spread and cover spaces between the display module and the base frame at the lateral ends of the display unit when the display module is in the curved state. | 07-09-2015 |
Patent application number | Description | Published |
20090075352 | Method For Improving A Strain Based On In-Silico Analysis - The present invention is related to a method for improving a strain on the basis of in silico analysis, in which it compares the genomic information of a target strain for producing a useful substance to the genomic information of a strain overproducing the useful substance so as to primarily screen genes unnecessary for the overproduction of the useful substance, and then to secondarily screen genes to be deleted through performing simulation with metabolic flux analysis. According to the present invention, an improved strain can be effectively constructed by the metabolic and genetic engineering approach comprising comparatively analyzing the genomic information of a target strain for producing a useful substance and the genomic information of a strain producing a large amount of the useful substance to screen candidate genes and performing in silico simulation on the screened candidate genes to select a combination of genes to be deleted, which shows an improvement in the production of the useful substance. Accordingly, the time, effort and cost required for an actual wet test can be significantly reduced. | 03-19-2009 |
20090215048 | METHOD OF IN-SILICO IMPROVEMENT OF ORGANISMS USING THE FLUX SUM OF METABOLITES - The present invention relates to an in silico method for improving an organism on the basis of the flux sum (φ) of metabolites, and more particularly to a method for screening key metabolites that increase the production yield of a useful substance, the method comprising defining the metabolite utilization of an organism for producing a useful substance as flux sum and perturbing the flux sum, as well as a method for improving an organism producing a useful substance, the method comprising deleting and/or amplifying genes associated with the aforementioned screened key metabolites. According to the present invention, the correlation between specific metabolites and useful substance production can be exactly predicted, so that it is possible to develop an organism having increased useful substance production by introducing and/or amplifying and/or deleting genes expressing enzymes associated with the specific metabolites. In addition, it is also possible to increase the production of a useful substance by adding specific metabolites during culture. | 08-27-2009 |
20090305328 | METHOD OF IMPROVEMENT OF ORGANISMS USING PROFILING THE FLUX SUM OF METABOLITES - The present invention relates to a method for improving an organism through the profiling of flux sum of metabolites, and more particularly to a method for screening key metabolites, the method comprises: plotting a profile between objective functions based on useful substance formation rate as a main function through an algorithm perturbing other functions influencing the production of useful substance; determining the utilization (flux sum (Φ)) of all metabolites from the profile; and screening key metabolites, which show an increase in flux sum (Φ) with an increase in useful substance formation rate. The present invention also relates to a method for improving an organism producing a useful substance, the method comprises introducing and/or amplifying genes associated with the screened key metabolites or introducing the genes from the outside into the organism. According to the disclosed invention, the metabolic utilization (flux sum; Φ) of specific metabolites according to an increase in useful substance formation rate can be predicted, so that key metabolites in increasing the production of a useful substance can be screened. Also, it is possible to increase the production of a useful substance through the method of improving a target organism by introducing and/or amplifying genes associated with the screened metabolites or through the method of supplying the metabolites during the culture of the organism. | 12-10-2009 |
20150377810 | APPARATUS AND METHOD FOR PREVENTING MALFUNCTION IN AN ELECTRONIC DEVICE - A method for operation of an electronic device and an electronic device are provided. The method includes determining if an object is detected at a first terminal and a second terminal among a plurality of terminals of an ear jack. If the object is detected, the impedance of the second terminal is calculated, and a type of the object is determined according to the calculated impedance. | 12-31-2015 |