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Dong, PA
Charles Qu Dong, Dresher, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090068185 | Asthma associated factors as targets for treating atopic allergies including asthma and related disorders - A new gene in the calcium-activated chloride channel family has been discovered that is induced by IL-9, thereby providing a therapeutic target in IL-9 mediated development of atopic allergy, asthma-related disorders and cystic fibrosis. A method for the identification and use of small molecule inhibitors of this gene and its products to treat these disorders has also been discovered. The invention also includes a method for diagnosing susceptibility to, and assessing treatment of atopic allergy, asthma-related disorders by measuring the level of gene expression in biologic samples using antibody specific for this protein. | 03-12-2009 |
Chun Christine Dong, Macungie, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080295966 | Electrode Assembly For The Removal Of Surface Oxides By Electron Attachment - An apparatus and a method comprising same for removing metal oxides from a substrate surface are disclosed herein. In one particular embodiment, the apparatus comprises an electrode assembly that has a housing that is at least partially comprised of an insulating material and having an internal volume and at least one fluid inlet that is in fluid communication with the internal volume; a conductive base connected to the housing comprising a plurality of conductive tips that extend therefrom into a target area and a plurality of perforations that extend therethrough and are in fluid communication with the internal volume to allow for a passage of a gas mixture comprising a reducing gas. | 12-04-2008 |
| 20090008426 | Addition of D2 to H2 to Detect and Calibrate Atomic Hydrogen Formed By Dissociative Electron attachment - A method of detecting and calibrating dry fluxing metal surfaces of one or more components to be soldered by electron attachment using a gas mixture of reducing gas comprising hydrogen and deuterium, comprising the steps of: a) providing one or more components to be soldered which are connected to a first electrode as a target assembly; b) providing a second electrode adjacent the target assembly; c) providing a gas mixture comprising a reducing gas comprising hydrogen and deuterium between the first and second electrodes; d) providing a direct current (DC) voltage to the first and second electrodes to form an emission current between the electrodes and donating electrons to the reducing gas to form negatively charged ionic reducing gas and molecules of hydrogen bonded to deuterium; e) contacting the target assembly with the negatively charged ionic reducing gas and reducing oxides on the target assembly. Related apparatus is also disclosed. | 01-08-2009 |
| 20090223831 | Removal of Surface Oxides by Electron Attachment - The present invention relates to a method for removing metal oxides from a substrate surface. In one particular embodiment, the method comprises: providing a substrate, a first, and a second electrode that reside within a target area; passing a gas mixture comprising a reducing gas through the target area; supplying an amount of energy to the first and/or the second electrode to generate electrons within the target area wherein at least a portion of the electrons attach to a portion of the reducing gas and form a negatively charged reducing gas; and contacting the substrate with the negatively charged reducing gas to reduce the metal oxides on the surface of the substrate. | 09-10-2009 |
| 20090236236 | Removal of Surface Oxides by Electron Attachment - Described herein are a method and an apparatus for removing metal oxides from a substrate surface within a target area. In one particular embodiment, the method and apparatus has an energizing electrode which has an array of protruding conductive tips that are electrically connected by a conductive wire and separated into a first electrically connected group and a second electrically connected group wherein at least a portion of the conductive tips are activated by a DC voltage source that is negatively biased to generate electrons within the target area that attach to at least a portion of a reducing gas that is present in the target area to form a negatively charged reducing gas that contacts the treating surface to reduce the metal oxides on the treating surface of the substrate. | 09-24-2009 |
| 20110094679 | ELECTRODE ASSEMBLY FOR THE REMOVAL OF SURFACE OXIDES BY ELECTRON ATTACHMENT - An apparatus and a method comprising same for removing metal oxides from a substrate surface are disclosed herein. In one particular embodiment, the apparatus comprises an electrode assembly that has a housing that is at least partially comprised of an insulating material and having an internal volume and at least one fluid inlet that is in fluid communication with the internal volume; a conductive base connected to the housing comprising a plurality of conductive tips that extend therefrom into a target area and a plurality of perforations that extend therethrough and are in fluid communication with the internal volume to allow for a passage of a gas mixture comprising a reducing gas. | 04-28-2011 |
Dennis Dong, Berwyn, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090171072 | Process for Preparing Unaggregated Antibody FC Domains - Methods useful for producing a solution of purified Fc peptide chains are disclosed. The methods employ protein A chromatography to separate high molecular weight, aggregated peptide chains comprising antibody Fc domains from lower molecular weight unaggregated peptide chains that also comprise antibody Fc domains. The solutions of purified Fc peptide chains obtained by the methods of the invention contain less than 5% aggregate and greater than 70% of the Fc peptide chains subjected to purification. | 07-02-2009 |
Dennis L. Dong, Berwyn, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080279816 | HOMOGENEOUS PREPARATIONS OF IL-28 AND IL-29 - Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity. | 11-13-2008 |
| 20100104531 | HOMOGENEOUS PREPARATIONS OF IL-28 AND IL-29 - Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity. | 04-29-2010 |
Feng Dong, Lansdale, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090232795 | 1B20 PCSK9 ANTAGONISTS - Antagonists of human proprotein convertase subtilisin-kexin type 9 (“PCSK9”) are disclosed. The disclosed antagonists are effective in the inhibition of PCSK9 function and, accordingly, present desirable antagonists for use in the treatment of conditions associated with PCSK9 activity. The present invention also discloses nucleic acid encoding said antagonists, vectors, host cells, and compositions comprising the antagonists. Methods of making PCSK9-specific antagonists as well as methods of using the antagonists for inhibiting or antagonizing PCSK9 function are also disclosed and form important additional aspects of the present disclosure. | 09-17-2009 |
| 20090246192 | 1D05 PCSK9 antagonists - Antagonists of human proprotein convertase subtilisin-kexin type 9 (“PCSK9”) are disclosed. The disclosed antagonists are effective in the inhibition of PCSK9 function and, accordingly, present desirable antagonists for use in the treatment of conditions associated with PCSK9 activity. The present invention also discloses nucleic acid encoding said antagonists, vectors, host cells, and compositions comprising the antagonists. Methods of making PCSK9-specific antagonists as well as methods of using the antagonists for inhibiting or antagonizing PCSK9 function are also disclosed and form important additional aspects of the present disclosure. | 10-01-2009 |
Hongchen Dong, Pittsburgh, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100227162 | Atom transfer radical polymerization (ATRP) based inorganic polymer structures - A modified inorganic substrate having a plurality of grafts of a polyalkyl acrylate or methacrylate of mean alkyl pendant chain length of 6 to about 40 carbons extending therefrom. The modified inorganic substrate is preferably a modified silica substrate and more preferably modified silica nanoparticles. There is also a process for graft polymerizing a silica substrate. | 09-09-2010 |
Lun Dong, Philadelphia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090117911 | Cooperative Base Stations in Wireless Networks - The embodiments of the invention provide an adaptive method for base station cooperation in a wireless network. In a multi-user communications network that includes base stations, and in which each base station is associated with a cell, and in which each cell includes one or more mobile stations, each base station determines pre-coding matrices for full-cooperation, semi-cooperation and non-cooperation. Each base stations also determines a sum rate SR | 05-07-2009 |
Xingwen Dong, Wayne, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090317388 | Tl1a in treatment of disease - Methods of modulating TL1A for the treatment of disease are disclosed. | 12-24-2009 |