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Donald, GB

Alastair Donald, Oxfordshire GB

Patent application numberDescriptionPublished
20090099213Ortho-Condensed Pyridine and Pyrimidine Derivatives (e.g., Purines) as Protein Kinases Inhibitors - The invention provides a compound for use in the prophylaxis or treatment of a disease state or condition mediated by protein kinase B, the compound having the formula (I): or salts, solvates, tautomers or N-oxides thereof, wherein T is N or CR04-16-2009

Alastair Donald, Abingdon GB

Patent application numberDescriptionPublished
20090247538Ortho-Condensed Pyridine and Pyrimidine Derivatives (e.g., Purines) as Protein Kinases Inhibitors - The invention provides a compound for use as a protein kinase B inhibitor, the compound being a compound of the formula (I) or salts, solvates, tautomers or N-oxides thereof, wherein T is N or CR10-01-2009

Alastair David Graham Donald, Oxfordshire GB

Patent application numberDescriptionPublished
20100010010HDAC INHIBITORS - Compounds of formula (I) inhibit HDAC activity, wherein A, B and D independently represent ═C— or ═N—; W is a divalent radical —CH═CH— or CH01-14-2010

Alistair David Graham Donald, Oxfordshire GB

Patent application numberDescriptionPublished
20090291978Enzyme Inhibitors - Compounds of formula (I) are inhibitors of histone deacetylase activity, and are useful in the treatment of, for example, cancers, wherein R11-26-2009
20100317678HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE - Compounds of formula (I), and salts, N-oxides, hydrates and solvates thereof are histone deacetylase inhibitors and are useful in the treatment of cell proliferative diseases, including cancers:12-16-2010
20100317865ENZYME AND RECEPTOR MODULATION - Covalent conjugates of an α,α-disubstituted glycine ester and a modulator of the activity of a target intracellular enzyme or receptor, wherein the ester group of the conjugate is hydrolysable by one or more intracellular carboxylesterase enzymes to the corresponding acid and the α,α-disubstituted glycine ester is conjugated to the modulator at a position remote from the binding interface between the inhibitor and the target enzyme or receptor pass into cells and the active acid hydrolysis product accumulates within the cells.12-16-2010

Alistair Ross Donald, Somerset GB

Patent application numberDescriptionPublished
20100186964Connection device - A connection device comprises a lock component of non-circular cross-sectional shape, the lock component being both angularly and axially moveable relative to a housing, stop means operable to limit angular movement of the lock component relative to the housing, the lock component having a threaded drive region, and a drive nut in threaded engagement with the drive region, wherein angular movement of the drive nut relative to the housing when the stop means are not engaged is able to drive the lock component for angular movement, rotation of the drive nut when the stop means are engaged causing axial displacement of the lock component relative to the housing.07-29-2010

Barrow-Williams Timothy Donald, St. Albans GB

Patent application numberDescriptionPublished
20120065593Injection Device - An injection device 03-15-2012

Craig Samuel Donald, Macclesfield GB

Patent application numberDescriptionPublished
20100317653OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS - Compounds of formula (I), and salts and pro-drugs thereof:12-16-2010

David Donald, Leicestershire GB

Patent application numberDescriptionPublished
20090042942Muscarinic Receptor Antagonists - The invention provides compounds of formula (I), wherein R02-12-2009

Malcolm Roger Curzon Donald, Dumfreisshire GB

Patent application numberDescriptionPublished
20110179746Flooring element - A method of making a flooring element. The flooring element is a tile formed of a polymer with embedded filler material. The filler material includes abrasive particles adjacent the top surface and a resilient or rubber-like material. The bottom surface of the tile includes a plurality of particles embedded in and extending from the bottom, which enables the tile to be securely adhered to a substrate. One embodiment of a method of making the tile includes adding a first layer containing a filler material to a mold, vibrating the mold to cause the heavier filler material to sink, applying a plurality of particles to the top of the polymer mixture in the mold, and polymerizing the mixture in the mold. In another embodiment, a second layer including resilient particles is added to the mold above the first layer before the mold is vibrated.07-28-2011