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Dominique A.
Dominique A. Fontanilla, Madison, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20100179111 | SIGMA-1 RECEPTOR LIGANDS AND METHODS OF USE - The invention provides compounds of formula I and compositions thereof. The invention further provides methods of using the compounds and compositions. The compounds of the invention can provide high affinity binding to sigma-1 receptors in a mammal. The compounds can exhibit selectivity for the sigma-1 receptor over the sigma-2 receptor. The compounds and compositions of the invention can also be used to treat conditions that involve the sigma-1 receptor, such as addiction, cardiovascular conditions, and cancer, for example, cancer of the breast, lung, prostate, ovarian, colorectal, or the CNS. | 07-15-2010 |
Dominique A. Rothenfluh, Lausanne CH
| Patent application number | Description | Published |
|---|---|---|
| 20100080850 | POLYPEPTIDE LIGANDS FOR TARGETING CARTILAGE AND METHODS OF USE THEREOF - Ligands that specifically bind to articular cartilage tissues are disclosed, including uses for targeting therapeutics towards articular cartilage tissue and new materials for articular cartilage. The ligands are effective in vivo to target therapeutic materials to articular cartilage. | 04-01-2010 |
Dominique A. Skovland, Copenhagen DK
| Patent application number | Description | Published |
|---|---|---|
| 20110091950 | POLYPEPTIDES HAVING ALPHA-GLUCURONIDASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME - The present invention relates to isolated polypeptides having alpha-glucuronidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. | 04-21-2011 |