Domenicali
Claudio Domenicali, Bologna IT
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20150114743 | MOTORCYCLE WITH LATERAL SHOCK-ABSORBING DEVICE - A motorcycle including a frame with a median plane, one front wheel and one rear wheel, each wheel including a hub with its own longitudinal spindle onto which is fitted a rim carrying a tyre, the hub associated with a fork and at least one brake disc, the rim integral with a cylindrical portion fitted onto the hub. The hub having at one of its first lateral ends a protruding collar a distance from a corresponding first end of said the cylindrical portion, the second end of the hub cooperating with a flange also having a collar located at a distance from a second end of the cylindrical portion. Between the ends of the rim cylindrical portion and the above-mentioned hub collars and the flange are annular or cylindrical elastically deformable elements capable of absorbing stresses directed in lateral directions relative to the frame median plane. | 04-30-2015 |
Peter Domenicali, Wilmington, MA US
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20080198355 | Surface measurement of in-vivo subjects using spot projector - The invention provides for surface mapping of in-vivo imaging subjects using a single camera and an illuminator that projects a plurality of targets such as spots on the subject. By limiting the depth-of-field of the camera lens, or of the illuminator optics, or both, a spatial plane is defined in which the spots are most sharply in focus. Controlled displacement of this plane relative to the subject is achieved through movement of the mechanical stage on which a subject is placed; or through movement of the best-focus plane by adjustment of the camera, lens, or illuminator optics. Images are taken at several relative positions of the best-focus plane and the subject, and the height of individual points on the subject is determined through analysis of focus, given the known displacements. A mesh or other surface can be constructed from individual point locations, to provide a surface map of the subject. Accuracy of 0.5 mm can be readily attained for mice and similarly sized subjects. | 08-21-2008 |
20080204697 | Surface measurement apparatus and method using depth of field - The invention provides for surface mapping of in-vivo imaging subjects using a single camera and a moveable stage on which a subject animal for in-vivo imaging is placed. Images are taken and the stage is moved by known amounts along the optical axis, and the heights of individual features on the subject are determined through analysis of focus, given the known stage displacement. Alternatively, height of sub-regions of the subject are determined through analysis of focus. A mesh or other surface can be constructed from individual features, to provide a surface map of the subject. Accuracy of 0.5 mm or better can be attained for mice and similarly sized subjects. | 08-28-2008 |
Peter Domenicali, Concord, MA US
Patent application number | Description | Published |
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20120108982 | SYSTEMS AND METHODS FOR IN-VIVO OPTICAL IMAGING AND MEASUREMENT - Disclosed are methods and systems for: (i) sequentially illuminating a specimen with different spatial distributions of light, wherein each illumination causes an object embedded in the specimen to emit radiation in response to the light; (ii) for each different spatial distribution of illumination light, imaging the radiation emitted from the specimen from each of multiple sides of the specimen; and (iii) determining information about the object in the specimen based on the imaged radiation from each of the multiple sides for each of the different spatial distributions of illumination light. | 05-03-2012 |
Peter Domenicali, Box Elder, SD US
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20150253224 | SUBSTRATE FOR SAMPLE HANDLING - An automated microscopy system having a sample applicator configured to dispense a sample, a flexible ribbon having a surface configured to receive the sample, a light receiver, such as, for example, an automated microscope, and a ribbon controller configured to receive the flexible ribbon and guide the ribbon from the sample applicator to the light receiver. A monolayer of cells can be formed on a hydrophilic portion of the flexible ribbon and can be transported using the ribbon controller to the light receiver for analysis. The cell monolayer can be continuous. | 09-10-2015 |