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Domb, IL
Abraham Domb, Efrat IL
| Patent application number | Description | Published |
|---|---|---|
| 20090035349 | Composite scaffolds and methods using same for generating complex tissue grafts - A composite scaffold for engineering a heterogeneous tissue is provided. The composite scaffold includes: (a) a first scaffold being capable of supporting formation of a first tissue type thereupon; and (b) a second scaffold being capable of supporting formation of a second tissue type thereupon; wherein the first scaffold and the second scaffold are arranged with respect to each other such that when the first scaffold supports the first tissue type and the second scaffold supports the second tissue type, a distance between any cell of the second tissue type and the first tissue type does not exceed 200 μm. | 02-05-2009 |
| 20090264892 | Methods, Materials and Apparatus for Treating Bone or Other Tissue - A method of treating a vertebra, comprising: | 10-22-2009 |
| 20090264942 | Methods, Materials and Apparatus for Treating Bone and Other Tissue - A method of treating a vertebra, comprising: | 10-22-2009 |
Abraham Jackob Domb, Jerusalem IL
| Patent application number | Description | Published |
|---|---|---|
| 20090318339 | Biodegradable polymers having a pre-determined chirality - Optically active polymers that are composed of monomer residues derived from chiral pre-polymerized monomers, which maintain the chirality of the pre-polymerized monomers upon polymerization are disclosed. These polymers can be composed of monomer residues that are derived from readily available chiral monomers and can be designed to have pre-determined characteristics such as chirality, biodegradability and functionality. Uses of these polymers as therapeutically active agents, and/or as carriers of therapeutically active agents, for delivering the active agents to a targeted bodily site and/or for a sustained release of the active agent, are further disclosed. Also disclosed are processed of preparing the polymers, compositions and medical devices containing the polymers, and conjugates of these polymers and various agents. | 12-24-2009 |
Abraham Jackob Domb, Efrat IL
| Patent application number | Description | Published |
|---|---|---|
| 20090111732 | Gelling Hydrophobic Injectable Polymer Compositions - Biodegradable carriers synthesized from ricinoleic acid oligoesters and aliphatic molecules having at least one carboxylic acid and at least one hydroxy or carboxylic acid group that are liquids or pastes at temperatures below 37° C. and methods of making and using thereof are described herein. The polymers described herein significantly increase their viscosity upon immersion in aqueous medium. These polymers can be used as hydrophobic biomedical sealants, temporary barriers to prevent adhesions, such as organ to organ adhesion, cell supports, carriers for drug delivery, and coatings on implantable medical devices, such as stents. The polymers made from ricinoleic acid oligoesters are less viscous and easier to inject compared to polymers of similar composition and molecular weight prepared from ricinoleic acid monomers, possess a higher molecular weight, retain an incorporated drug for longer periods, and degrade into soft degradation products at a slower rate compared with polymers synthesized from ricinoleic acid monomers. Pharmaceutically active agents can be incorporated into the liquid or pastes without the use of organic solvents. | 04-30-2009 |
Avi Domb, Efrat IL
| Patent application number | Description | Published |
|---|---|---|
| 20110104287 | FENOLDOPAM FORMULATIONS AND PRO-DRUG DERIVATIVES - Formulations of fenoldopam are disclosed for repeated administration or continued slow release administration, over prolonged periods of time or targeted slow and regulated delivery. The formulations include those formulations that increase the bioavailability of fenoldopam after oral intake, particularly lipid based nano dispersions and pronanodispersions and surfactant rich formulations. This may be accomplished by entrapment in nanoparticles or liposomal formulations or conjugation to a polymer or small molecule via a soft bond. | 05-05-2011 |
Avraham Jacob Domb, Efrat IL
| Patent application number | Description | Published |
|---|---|---|
| 20100092406 | Systems, Methods, and Compositions for Treatment and Use of a Palatal Patch - Devices and methods for a palatal patch include a tablet or strip having a bioadhesive component and an active component. The bioadhesive component allows for the palatal patch to be attached to an upper palate, and for the active component to be released into the oral cavity and/or GI tract. Compositions for the active component include compositions for treatment of halitosis, anti-acids, vitamins, anti-smoking agents, and others. A composition for treatment of halitosis includes at least one of Echinacea, Lavender, Mastic Gum and Sage. A device for delivery of the palatal patch to the upper palate includes a housing and a piston, the piston having a holder for the palatal patch, and wherein the piston may be configured to move distally so as to delivery the palatal patch to the upper palate. | 04-15-2010 |
Nir Domb, Ramat Hasharon IL
| Patent application number | Description | Published |
|---|---|---|
| 20100006608 | Device for Aromatic Additions to Clothes Hangers and Towel Hooks - Containers for aromatic additions to clothes hangers and towel hooks. Perforated pocket on the hanger that is openable to insert replacement aroma pads. Perforated sides of a double walled towel hook to insert aroma pad between the walls. | 01-14-2010 |