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Dobson, GB

Andrew Hornby Dobson, Macclesfield GB

Patent application number	Description	Published
20090286982	NOVEL SALT-554 - 4-(3-chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N-methylcarbamoylmethyl)piperidin-4-yl]oxy}quinazoline difumarate, pharmaceutical compositions containing the difumarate, the use of the difumarate in the treatment of hyperproliferative disorders such as cancer and processes for the manufacture of the difumarate are described.	11-19-2009
20110207745	SOLID FORMS OF 4--N,N-DIETHYLBENZAMIDE, COMPOSITIONS THEREOF, AND USES THEREWITH - Solid forms comprising salts of 4-{(R)-(3-aminophenyl)[4-(4-fluorobenzyl)piperazin-1-yl]methyl}-N,N-diethylbenzamide, compositions comprising the solid forms, methods of making the solid forms, and methods of their use for the treatment of various diseases and/or disorders are provided herein.	08-25-2011
20120035363	CRYSTALLINE 4-(3-CHLORO-2-FLUOROANILINO)-7 METHOXY-6-... - 4-(3-chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N-methylcarbamoylmethyl)piperidin-4-yl]oxy}quinazoline difumarate, pharmaceutical compositions containing the difumarate, the use of the difumarate in the treatment of hyperproliferative disorders such as cancer and processes for the manufacture of the difumarate are described.	02-09-2012

Benjamin Charles Dobson, Macclesfield GB

Patent application number	Description	Published
20090318434	COMPOSITION AND PROCESS - 356 - There is provided a process for the preparation of a compound of Formula 1,	12-24-2009

Catherine A. Dobson, Hull GB

Patent application number	Description	Published
20090283098	SPEECH VALVE - A speech valve comprises a generally cylindrical body and a closure member which is slidably movable within the body between a closed position and an open position. The valve body and the closure member are formed of a rigid, smooth material which is resistant to the growth of biofilm such as a ceramic. A particular suitable ceramic is partially stabilised zirconia. The valve body is provided with an outer sleeve which is provided with radially outward extending annular flanges, which are used to retain the speech valve in a fistula between the oesophagus and the trachea.	11-19-2009

Christopher Dobson, Cambridgeshire GB

Patent application number	Description	Published
20080262742	COMPUTATIONAL METHOD AND APPARATUS FOR PREDICTING POLYPEPTIDE AGGREGATION OR SOLUBILITY - A prediction method for predicting the effect of an amino acid modification on the rate of aggregation (solubility) of a reference polypeptide comprising: calculating the difference in hydrophobicity (ΔHydr) between the reference polypeptide and a modified polypeptide, calculating the difference in β-sheet propensity (ΔΔG	10-23-2008
20090203535	ACOUSTIC WAVE TRANSDUCER SUBSTRATE AND MEASUREMENTS USING THE SAME - An acoustic wave transducer substrate is provided, the substrate having a surface with a plurality of growth promotion sites for promoting the accumulation of polypeptide molecules at said sites. The growth-promotion sites are preferably for promoting fibril formation. The invention also provides a method of screening a candidate compound for an effect on fibril growth, including the steps of: providing an acoustic wave transducer substrate having a surface with a plurality of growth promotion sites for promoting the accumulation of polypeptide molecules at said sites; causing oscillation of the substrate; contacting the substrate surface with a sample fluid comprising polypeptide molecules and a candidate compound; and measuring one or more parameters of the substrate oscillation to monitor the accumulation of said polypeptide molecules of interest in the presence and absence of said candidate compound. Alteration of the accumulation of said polypeptide molecules of interest in the presence of said candidate compound as compared with that in the absence of said candidate compound indicates that the candidate compound has an effect of fibril growth.	08-13-2009
20110035155	PROTEIN AGGREGATION PREDICTION SYSTEMS - We describe methods for identifying aggregation-prone regions in structured—that is folded—proteins. Embodiments of the method use a local propensity for aggregation (A	02-10-2011

Claire Dobson, Cambridge GB

Claire Louise Dobson, Cambridge GB

Patent application number	Description	Published
20090060919	BINDING MEMBERS FOR IgE MOLECULES - This invention relates to binding members, especially antibody molecules, for IgE. The binding members are useful for, inter alia, treatment of disorders mediated by IgE including allergies and asthma.	03-05-2009
20090202568	Binding members for interleukin-4 receptor alpha (IL-4Ra)-173 - Binding members, especially antibody molecules, for interleukin (IL)-4 receptor alpha (IL-4Rα), and their therapeutic use e.g. in treating or preventing disorders associated with IL-4Rα, IL-4 and/or IL-13, examples of which are asthma and COPD.	08-13-2009

Curtis Dobson, Manchester GB

Patent application number	Description	Published
20080207508	Treatment of Fungal and/or Protist Infections - The present invention relates to the use of a polypeptides, comprising repeats of a peptide derived from a Heparan Sulphate Proteoglycan (HSPG) receptor binding region of an apolipoprotein, for treating or preventing a fungal and/or protist infection. The invention further relates to the use of such peptides for treating or preventing the contamination of surfaces or objects with such peptides.	08-28-2008
20090048171	Treatment of viral infections - The present invention relates to polypeptides, and derivatives or analogues thereof, comprising a tandem repeat of apolipoprotein B, or a truncation thereof, derived from an HSPG receptor binding region of apolipoprotein B. Such peptides are useful for treating or preventing the development of viral infections.	02-19-2009
20100221273	TREATMENT OF VIRAL INFECTIONS - The present invention concerns polypeptides derived from a tandem repeat of apoE	09-02-2010

Ian Dobson, London GB

Patent application number	Description	Published
20100152496	Process, Plant And Butanol From Lignocellulosic Feedstock - This invention relates to a process, a plant, and butanol made of or derived from lignocellulosic feedstock. The process includes the step of depolymerizing lignocellulosic material to form pentose and a remainder. The process also includes the step of converting the pentose to butanol material and using the remainder for generation of power or further downstream conversion.	06-17-2010
20100251608	Process, Plant, and Biofuel From Lognocellulosic Feedstock - This invention relates to a process and a plant for biofuel production, such as with biogasoline and/or biodiesel. The process includes the step of depolymerizing lignocellulosic material to form pentose and a remainder. The process also includes the step of converting the pentose to a biofuel material and using the remainder for generation of power or further downstream conversion.	10-07-2010

Janet L. Dobson, Cambridge GB

Patent application number	Description	Published
20110254865	APPARATUS AND METHODS FOR DYNAMICALLY CORRELATING VIRTUAL KEYBOARD DIMENSIONS TO USER FINGER SIZE - Embodiments provide user interface for computing devices equipped with a touchscreen user interface/display and a digital camera that enhances a portion of a displayed image within a user's gaze. A user may calibrate their mobile device by touching a portion of the touchscreen with one or more fingers and following a moving image on the display with their eyes. The mobile device may track where a user is looking, and if the user is looking at the mobile device display, a portion of the display in the vicinity of the user's gaze may be enhanced in size. In an embodiment, if the user is looking at a virtual keyboard, key icons near the user's gaze may be increased in size commensurate with the user's finger tip size. The in this manner, a user can accurately select individual keys in a virtual keyboard that fits within a mobile device display.	10-20-2011

Janet L. Dobson, Linton GB

Patent application number	Description	Published
20120078746	SYSTEMS AND METHODS FOR DISCOVERY OF RELATED INTERACTABLE ITEMS IN A MOBILE STORE ENVIRONMENT - Methods and apparatus for providing interactable item suggestions may include selecting a seed interactable item and determining a first set of one or more interactable items related to the seed interactable item based on one or more data sources. The methods and apparatus may further include generating a graphical presentation with a first set of interactable items with the seed interactable item and the one or more related interactable items. The methods and apparatus may also include generating a new graphical presentation of a second set of one or more interactable items related to a selected interactable item.	03-29-2012

Jon Dobson, Stoke-On-Trent GB

Patent application number	Description	Published
20080286361	Gene Delivery - The present invention relates to a method of delivery of a therapeutic agent to a target cell the method comprising targeting particles comprising the therapeutic agent to the cell using magnetic means to apply a magnetic force to said particles so as to tend to move said particles towards said magnetic means and at the same time moving said magnetic means.	11-20-2008
20090123366	Targeted Therapy - In order to target a diseased material in a subject, a monocyte, or monocyte-derived cell, such as a macrophage, which incorporates a magnetic material, such as a magnetic particle or a ferrofluid, preferably having a biocompatible coating, is proposed to be administered. A magnetic energy source may then be applied to the subject to destroy, rupture or inactivate the diseased material. Alternatively, the monocyte or monocyte derived cell may additionally include a therapeutic agent, which is thereby targeted at the diseased material.	05-14-2009
20110034753	STEM CELL TARGETING AND ACTIVATION USING MAGNETIC PARTICLES - The present invention provides a method of selectively activating and/or targeting stem cells which enables the cells to then be manipulated mechanically in a remote manner wherein the method comprises magnetically manipulating a stem cell in vivo or in vitro by the association of a magnetisable particle within the stem cell.	02-10-2011

Jon Dobson, Staffordshire GB

Patent application number	Description	Published
20100298816	MAGNETIC DELIVERY DEVICE - A method of delivering a reagent into a cell comprising positioning at least one cell, and at least one magnetically susceptible particle attached to the reagent, in the magnetic field of a Halbach array such that the magnetically susceptible particle is attracted to and contacts the cell is described together with an apparatus for delivery of the reagent.	11-25-2010

Louise Claire Dobson, Cambridge Cambridgeshire GB

Patent application number	Description	Published
20100150904	BINDING MEMBERS FOR IGE MOLECULES - This invention relates to binding members, especially antibody molecules, for IgE. The binding members are useful for, inter alia, treatment of disorders mediated by IgE including allergies and asthma.	06-17-2010
20110212084	BINDING MEMBERS FOR IGE MOLECULES - This invention relates to binding members, especially antibody molecules, for IgE. The binding members are useful for, inter alia, treatment of disorders mediated by IgE including allergies and asthma.	09-01-2011

Matthew John Dobson, Malmesbury GB

Patent application number	Description	Published
20110214248	VACUUM CLEANING HEAD - A vacuum cleaning head includes a housing having a suction opening for admitting an air flow to the head, an agitator for agitating a surface to be cleaned, the agitator having an active state and an inactive state, a duct for receiving the air flow from the housing, and a control assembly for controlling the state of the agitator. The control assembly includes a pressure chamber having an interior volume in fluid communication with the duct and which is variable between an expanded configuration and a contracted configuration in response to a pressure difference between the interior volume and ambient air, an actuator for effecting a transition of the agitator from one of the active state and the inactive state to the other of the active state and the inactive state in response to a transition of the pressure chamber to the contracted configuration, and a control mechanism having a first state for preventing the pressure chamber from adopting the contracted configuration, and a second state for allowing the pressure chamber to adopt the contracted configuration. The control mechanism is arranged to change between the first and second states in response to an increase in the interior volume of the pressure chamber, for example in response to an increase in the air pressure within the duct.	09-08-2011
20110214249	VACUUM CLEANING APPLIANCE - A vacuum cleaning appliance includes a vacuum cleaning head having a suction opening, the head having a first state and a second state, a fan unit for drawing an air flow through the suction opening, and a control assembly for controlling the state of the head. The control assembly includes a user-operable valve for increasing temporarily an air pressure within an airflow path extending from the suction opening to the fan unit, a pressure chamber having an interior volume in fluid communication with the airflow path, the pressure chamber being moveable from an expanded configuration to a contracted configuration in response to a pressure difference between the interior volume and ambient air, the pressure chamber being biased towards the expanded configuration, and a control mechanism for allowing the pressure chamber to move to the contracted configuration in response to a first operation of the valve to place the head in one of the first and second states, and for preventing the pressure chamber from returning to the contracted configuration in response to a second operation of the valve to place the head in the other of the first and second states.	09-08-2011
20110214250	HANDLE FOR A WAND OF A VACUUM CLEANING APPLIANCE - A handle for a wand of a vacuum cleaning appliance includes a handgrip portion and a conduit for receiving an air flow. The handle includes an aperture for admitting ambient air into the conduit. A first valve occludes a first portion of the aperture, and a second valve occludes a second portion of the aperture. A control mechanism moves the first and second valves away from the aperture to admit ambient air into the conduit. To vary the air flow into the conduit, the control mechanism includes a first manually operable actuator located on the handle for moving both of the first and second valves away from the aperture, and a second manually operable actuator is located on the handle for moving only one of the first and second valves away from its respective portion of the aperture.	09-08-2011
20110214252	VACUUM CLEANING HEAD - A vacuum cleaning head includes a pressure chamber having a first chamber section and a second chamber section which is moveable relative to the first chamber section in response to a pressure differential thereacross from a first position to a second position, and a control mechanism located within the pressure chamber. The control mechanism has a first state for inhibiting the movement of the second chamber section in response to said pressure differential beyond a third position intermediate the first and second positions, and a second state for allowing the second chamber section to move in response to said pressure differential to the second position. The control mechanism is arranged to change between the first and second states in response to a movement of the second chamber section from the third position. This can allow the pressure chamber to toggle between different configurations through varying the pressure differential across the second chamber section, for example to raise or lower part of the cleaner head, or to selectively activate or deactivate an agitator.	09-08-2011

Matthhew Dobson, Oxfordshire GB

Patent application number	Description	Published
20110192476	Water Purification Apparatus and Method - A water purification apparatus comprising at least: (a) one or more water purification components to provide a purified water stream, preferably having a conductivity of less than 1 μS/cm; and (b) a stepper motor (	08-11-2011

Nigel Dobson, Bradford GB

Patent application number	Description	Published
20090261091	BACK BOX - An electrical socket back box	10-22-2009

Peter Dobson, Derby GB

Patent application number	Description	Published
20100281662	Filling Fiber With Improved Opening Performance, Method For Its Production And Its Use - The present invention relates to a process for producing a cellulosic fiber, in particular a lyocell fiber which has improved opening characteristics and therefore is particularly useful for blending with feathers, in particular with down, to such a fiber fill fiber and to the use of this fiberfill fiber in mixtures for bedding and clothing.	11-11-2010
20110171865	CELLULOSE FIBER AND PROCESS FOR THE PRODUCTION THEREOF - The invention concerns a cellulose fiber of the genus Lyocell which is treated with a cross-linking agent, with the cross-linking agent inducing a protection from fibrillation on the fiber and exhibiting the following properties:	07-14-2011

Peter Dobson, Rowledge GB

Patent application number	Description	Published
20110306006	DEVICE FOR PROVIDING A FLOW OF ACTIVE GAS	12-15-2011

Peter Dobson, Oxfordshire GB

Patent application number	Description	Published
20120040175	COATED SUBSTRATE - Methods for coating a substrate are disclosed, the methods comprising providing a substrate, providing pre-formed nanoparticles of an inorganic material, providing at least one precursor of a first metal oxide, and depositing a coating on at least one surface of the substrate by contacting the surface with the precursor of the metal oxide and pre-formed nanoparticles. Also disclosed are substrates coated using such a method. The coated substrates are coloured. Preferably the metal oxide is a doped metal oxide to modify the thermal properties of the coating. The preferred nanoparticles are of platinum group metals or coinage metals.	02-16-2012

Peter James Dobson, Oxfordshire GB

Patent application number	Description	Published
20100092384	MULTIFUNCTIONAL NANOPARTICLES AND COMPOSITIONS AND METHODS OF USE THEREOF - Provided is a multifunctional particle comprising: (a) an inner metallic core, (b) a biocompatible shell comprising an optical contrast agent embedded therein, and (c) a targeting biomolecule conjugated to the biocompatible shell through a multidentate ligand, wherein the multidentate ligand is chelated to an imaging agent. Also provided are compositions comprising the multifunctional particle and methods of using the multifunctional particle, including a method of diagnostic imaging and a method of treatment.	04-15-2010

Phillip Stephen Dobson, Glasgow GB

Patent application number	Description	Published
20110157599	Uses of Electromagnetic Interference Patterns - Various uses of visible light interference patterns are provided. Suitable interference patterns are those formed by diffraction from patterns of apertures. Typical uses disclosed herein relate to spatial metrology, such as a translational and/or angular position determination system. Further uses include the analysis of properties of the light itself (such as the determination of the wavelength of the electromagnetic radiation). Still further uses include the analysis of one or more properties (e.g. refractive index) of the matter through which the light passes. Part of the interference pattern is captured at a pixellated detector, such as a CCD chip, and the captured pattern compared with a calculated pattern. Very precise measurements of the spacing between maxima is possible, thus allowing very precise measurements of position of the detector in the interference pattern.	06-30-2011

Richard James Dobson, Berkshire GB

Patent application number	Description	Published
20080226641	Outer surface proteins, their genes, and their use - According to the present invention, a series of genes are identified in Group B	09-18-2008
20090274717	Genes and proteins, and their use - According to the present invention, a series of genes are identified in Group B	11-05-2009

Robert Dobson, Edinburgh GB

Patent application number	Description	Published
20110286606	METHOD AND SYSTEM FOR NOISE CANCELLATION - A noise cancellation signal is generated based on detected ambient noise, such that the noise cancellation signal and a wanted sound signal can be applied to a speaker. Gain control is applied to the wanted sound signal based on a comparison between the detected ambient noise level and the wanted sound signal level, for example such that the level of the wanted sound signal after the gain has been applied exceeds the level of a detected ambient noise signal by a certain threshold. Steps may also be taken such that the total level of the wanted sound signal after the gain has been applied and of the detected ambient noise signal do not exceed a second threshold, to avoid saturating the speaker to which they are applied.	11-24-2011

Robert William Albert Dobson, Chiswick GB

Patent application number	Description	Published
20090075655	MOBILE PHONE NETWORK MANAGEMENT SYSTEMS - This invention relates to systems and methods for managing and optimizing mobile phone networks. A system for maintaining or optimizing a mobile phone network, the system includes a plurality of data feed inputs including at least one performance data feed input to receive performance data relating to performance of said mobile phone network over a first time period and at least one configuration data feed input to receive configuration data relating to configuration of said mobile phone network over a second time period; and a radio performance optimization system coupled to said plurality of data feed inputs, said radio performance optimization system including a rules engine to operate on said performance data and on said configuration data in accordance with a set of hierarchical rules and to output one or more tasks for network optimization, a said task including a definition of a potential fault, exception or optimization of said network to be investigated by a service engineer.	03-19-2009

Stephen Dobson, Skipton GB

Patent application number	Description	Published
20090049145	METHOD OF GENERATING AND DISPLAYING A MESSAGE AND AN APPARATUS FOR PERFORMING SUCH A METHOD - A method of generating and displaying a message comprising the steps of	02-19-2009

Timothy M. Dobson, Cambridge GB

Patent application number	Description	Published
20100146020	System and Method for the Parallelization of Saturated Accumulation Operations - A system and method for parallelization of saturated accumulation is provided. In the method, an input sequence is divided into a plurality of subsequences. For each subsequence, three parallel saturating additions are performed. The local saturation minimum is the saturating addition of the global saturation minimum and the values of the subsequence. The local midpoint is the saturating addition of the values of the subsequence and the local saturation maximum is the saturating addition of the global saturation maximum and the values of the subsequence. In embodiments, the accumulation total for a subsequence is calculated as the saturating addition of the accumulation total for prior subsequences and the local midpoint of the current subsequence, wherein the accumulation total of the last subsequence is the result of the saturated accumulation for the sequence. In another embodiment, the saturated addition of subsequence results are further parallelized before the final result is reached.	06-10-2010