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Dobler, US

Alfred Dobler, Brookfield, CT US

Patent application numberDescriptionPublished
20100077676ARCHITECTURAL PANEL HANGER - The device to hang an architectural panel on a wall preferably comprises a support structure having first and second surfaces and a circumferential surface therebetween, a hole between the first and second surfaces, and a screw having a head, shaft and plurality of threads about the shaft. The screw is located in the hole and connected to the support structure such that the head is at or below the first surface of the support structure and the shaft is perpendicular thereto. The device can be driven into a wall and will support an architectural panel locatable thereon. Specifically, a panel clip, attached to the back of the architectural panel, can be placed on the support structure and the device will support the panel placed thereon. The circumferential surface of the support structure preferably includes a bevel to facilitate the placement of the panel clip onto the support structure.04-01-2010

Darin Dobler, Oxnard, CA US

Patent application numberDescriptionPublished
20080302372METHODS FOR PRE-STRESSING AND CAPPING BIOPROSTHETIC TISSUE - A treatment for bioprosthetic tissue used in implants or for assembled bioprosthetic heart valves to reduce in vivo calcification is disclosed. The method includes preconditioning, pre-stressing, or pre-damaging fixed bioprosthetic tissue in a manner that mimics the damage associated with post-implant use, while, and/or subsequently applying a calcification mitigant such as a capping agent or a linking agent to the damaged tissue. The capping agent suppresses the formation of binding sites in the tissue that are exposed or generated by the damage process (service stress) and otherwise would, upon implant, attract calcium, phosphate, immunogenic factors, or other precursors to calcification. The linking agent will act as an elastic reinforcement or shock-absorbing spring element in the tissue structure at the site of damage from the pre-stressing. In one method, tissue leaflets in assembled bioprosthetic heart valves are preconditioned by simulating actual flow conditions for a predetermined number of cycles, during or after which the valve is exposed to the capping agent.12-11-2008

Darin Dobler, Aliso Viejo, CA US

Patent application numberDescriptionPublished
20110165675CAPPING BIOPROSTHETIC TISSUE TO REDUCE CALCIFICATION - A treatment for bioprosthetic tissue used in implants or for assembled bioprosthetic heart valves to reduce in vivo calcification. The method includes applying a calcification mitigant such as a capping agent or an antioxidant to the tissue to specifically inhibit oxidation in tissue. Also, the method can be used to inhibit oxidation in dehydrated tissue. The capping agent suppresses the formation of binding sites in the tissue that are exposed or generated by the oxidation and otherwise would, upon implant, attract calcium, phosphate, immunogenic factors, or other precursors to calcification. In one method, tissue leaflets in assembled bioprosthetic heart valves are pretreated with an aldehyde capping agent prior to dehydration and sterilization.07-07-2011

Kendall Lee Dobler, Loveland, OH US

Patent application numberDescriptionPublished
20090192344SURGICAL DEVICES FOR MANIPULATING TISSUE - A surgical kit can be used to manipulate tissue within the body of a patient to create a working space within the body to allow a surgeon to easily access and work within the body using various surgical instruments. A surgical kit can include an implant comprised of a magnetic material which can be engaged with tissue within the body. The kit can further include a surgical instrument having a magnet which can be used to manipulate the implant and tissue engaged therewith. A surgical kit can include an anchor and a hanger configured to engage tissue at different locations within the body and a connection member engaged with the anchor and the hanger such that the connection member can be pulled to move the anchor toward the hanger. A surgical instrument which utilizes a vacuum provided to one or more movable members can also be used to manipulate tissue.07-30-2009

Markus Dobler, Cambridge, MA US

Patent application numberDescriptionPublished
20080280766Pyridopyrazines for Combating Phytopathogenic Fungi - The compounds of the general formula (I) wherein R, R11-13-2008
20080287472Fungicides - Fungicidal compositions comprising derivatives of pyridopyrimidines having the general formula (1):11-20-2008
20080318962Fungicides Based on Nitrogen-Containing Heterocycles - The compound of the general formula (I), wherein W, X, Y, Z, R, R12-25-2008
20090069333FUNGICIDES - This invention relates to novel derivatives of pyridopyrazines and pyridopyridazines, to processes for preparing them, to intermediate chemicals used in their manufacture, to compositions containing them and to methods of using them to combat fungi, especially fungal infections of plants. The fungicidal compounds have the general formula (1) wherein R, R03-12-2009

Patent applications by Markus Dobler, Cambridge, MA US

Markus Rolf Dobler, Arlington, MA US

Patent application numberDescriptionPublished
20080255149Carboxyamine Compounds and Methods of Use Thereof - The invention relates to the use of carboxyamine compounds and salts thereof in the treatment of HDAC dependent diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases.10-16-2008
20100120872ORGANIC COMPOUNDS AND THEIR USES - The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.05-13-2010

Sven Dobler, Farmingdale, NY US

Patent application numberDescriptionPublished
20110000873Fragrance slurry pad - The fragrance slurry pad receives a fragrance in slurry and prints the slurry into a recognizable logo, brand, or word upon a strip. To enhance the marketing impact of fragrance strip advertising and to differentiate among marketers without increase in cost, the present invention is fragrance slurry deposition pads that support and reinforce a marketing message. The preferred embodiment has a brand name, logo, or message etched into a flexographic print pad. The print pad applies the slurry to a strip located beneath a flap. Upon opening the flap, the fragrance slurry appears in a discernible pattern and visible message.01-06-2011