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Do, PA

Hiep Do, Sinking Spring, PA US

Patent application numberDescriptionPublished
20090130171High concentration gentian violet containing medical devices and methods of making same - Implantable medical devices, such as catheters, treated with a high concentration of gentian violet, and methods of preparing these medical devices are provided.05-21-2009
20100069854Elastomeric Devices Containing Chlorhexidine/Fatty Acid Salts Made From Fatty Acids of 12 to 18 Carbons - In a medical device, an antimicrobial agent is combined with an elastomeric polymer material. The antimicrobial agent includes at least one chlorhexidine/fatty acid salt which is a neutralization product of chlorhexidine base and a fatty acid having between 12 and 18 carbon atoms.03-18-2010
20100082097Article Containing Segregated Biguanide and Lewis Acid - A medical device includes a first region having a biguanide or a pharmaceutically acceptable salt thereof and a second region having a Lewis acid.04-01-2010
20100234815STABLE MELT PROCESSABLE CHLORHEXIDINE COMPOSITIONS - In a medical device having an antimicrobial agent, the medical device includes a base material and an amount of chlorhexidine or a pharmaceutically acceptable salt thereof disposed in the base material sufficient to reduce microbial growth. The base material is melt processed together with the chlorhexidine to generate the medical device which is substantially free of destabilized chlorhexidine.09-16-2010
20100298772TRANCUTANEOUS DEVICES AND KITS THAT PROVIDE CUES FOR LOCATION OF INSERTION SITE, EXIT SITE AND DEVICE PATH, AND METHODS OF USE - Transcutaneous devices are disclosed that self-provide cues for exact location of transcutaneous insertion sites, exit sites, and/or the track of the device between the sites, as are methods and kits for using the transcutaenous devices to mark the sites and track of the device and for removing location cues.11-25-2010

Patent applications by Hiep Do, Sinking Spring, PA US

Hiep Q. Do, Sinking Spring, PA US

Patent application numberDescriptionPublished
20090253889POLY(TRIMETHYLENE-ETHYLENE ETHER) GLYCOLS - Block poly(trimethylene-ethylene ether) glycols are disclosed. The block poly(trimethylene-ethylene ether) glycols can be prepared by the polycondensation of 1,3-propanediol reactant and polyethylene glycol reactant. The block poly(trimethylene-ethylene ether) glycols can be used in breathable membranes, synthetic lubricants, hydraulic fluids, cutting oils, motor oils, surfactants, spin-finishes, water-borne coatings, laminates, adhesives, packaging, films and foams, fibers and fabrics.10-08-2009
20090274764Hollow Foam Beads for Treatment of Glioblastoma - Compositions and methods for the treatment of tumors are disclosed. Specifically, the present invention provides hollow foam beads having a chemotherapeutic agent incorporated therein. A method of making such beads is disclosed. In addition, a method for treating a glioblastoma tumor and other types of tumors with the compressible hollow foam beads is disclosed.11-05-2009

Hung V. Do, New Hope, PA US

Patent application numberDescriptionPublished
20100119502THERAPY REGIMENS, DOSING REGIMENS AND STABLE MEDICAMENTS FOR THE TREATMENT OF POMPE DISEASE - The present application provides a method for treating Pompe disease in a subject in need thereof, that includes a method of administering to the subject a GAA enzyme in combination with an ASSC for the GAA enzyme. The present application also provides methods for increasing the in vitro and in vivo stability of a GAA enzyme formulation.05-13-2010
20110070643Utilization of Pharmacological Chaperones to Improve Manufacturing and Purification of Biologics - The present invention provides methods for improving the production of recombinant proteins through the use of pharmacological chaperones for the recombinant proteins. As exemplified by the present invention, the binding of a pharmacological chaperone to a recombinant protein expressed by a cell can stabilize the protein and increase export of the protein out of the cell's endoplasmic reticulum, and increase secretion of the protein by the cell.03-24-2011
20110136151ASSAYS FOR DIAGNOSING AND EVALUATING TREATMENT OPTIONS FOR POMPE DISEASE - Provided are in vitro, ex vivo and in vivo methods for determining whether a patient with Pompe disease will respond to treatment with a specific pharmacological chaperone.06-09-2011
20110143419Utilization of Pharmacological Chaperones to Improve Manufacturing and Purification of Biologics - The present invention provides methods for improving the production of recombinant proteins through the use of pharmacological chaperones for the recombinant proteins. As exemplified by the present invention, the binding of a pharmacological chaperone to a recombinant protein expressed by a cell can stabilize the protein and increase export of the protein out of the cell's endoplasmic reticulum, and increase secretion of the protein by the cell.06-16-2011
20110152319METHOD TO PREDICT RESPONSE TO PHARMACOLOGICAL CHAPERONE TREATMENT OF DISEASES - The present invention provides methods to determine whether a patient with a lysosomal storage disorder will benefit from treatment with a specific pharmacological chaperone. The present invention exemplifies an in vitro method for determining α-galactosidase A responsiveness to a pharmacological chaperone such as 1-deoxygalactonojirimycin in a cell line expressing a mutant from of α-galactosidase A. The invention also provides a method for diagnosing Fabry disease in patients suspected of having Fabry disease.06-23-2011