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Distefano, US

Daniel J. Distefano, Harleysville, PA US

Patent application numberDescriptionPublished
20110212130LIVE, ATTENUATED RESPIRATORY SYNCYTIAL VIRUS - The present invention features live, attenuated respiratory syncytial viruses (RSV) useful as vaccines against RSV infection and/or the development of severe RSV-associated illnesses. The disclosed viruses are attenuated to the extent of being nonpathogenic when administered to a subject but substantially retain the antigenic and immunogenic properties of wild-type RSV.09-01-2011

Eric Distefano, Livermore, CA US

Patent application numberDescriptionPublished
20100064162TECHNIQUES TO MANAGE OPERATIONAL PARAMETERS FOR A PROCESSOR - Techniques to manage operational parameters for a processor are described. For instance, a method includes monitoring performance values representing physical characteristics for multiple components of a computing platform, and managing a performance level for a processor based on the performance values and one or more operational parameters for the processor. The operational parameters may include one or more transitory operational parameters that cause the processor to temporarily exceed operational parameters set by a thermal design power limit. Other embodiments are described and claimed.03-11-2010
20100205464METHOD AND APPARATUS FOR ON-DIE TEMPERATURE SENSING AND CONTROL - For one disclosed embodiment, a plurality of processor cores may be on a semiconductor die. The processor cores may have at least one corresponding temperature sensor. Circuitry on the semiconductor die may generate thermal event indications based on sensed temperatures from multiple temperature sensors of multiple processor cores. A thermal event indication may indicate that a sensed temperature exceeds a temperature point. Central management logic on the semiconductor die may receive thermal event indications based on sensed temperatures from multiple temperature sensors of multiple processor cores. The central management logic may modify operation of one or more of the processor cores in response to a thermal event indication. Other embodiments are also disclosed.08-12-2010

Patent applications by Eric Distefano, Livermore, CA US

Frank Vito Distefano, Macungie, PA US

Patent application numberDescriptionPublished
20080214718HYDROPHOBIC METAL AND METAL OXIDE PARTICLES WITH UNIQUE OPTICAL PROPERTIES - Treating metal or metal oxides such as ZnO with PIBSA and analogous molecules yields a hydrophobic powder. The powder can provide improved optical clarity when incorporated into a polymer matrix in comparison to untreated hydrophilic ZnO.09-04-2008
20100096601Molecules with complexing groups for aqueous nanoparticle dispersions and uses thereof - Stable dispersions of nanoparticles and microparticles in liquids and method for their preparation are disclosed. The dispersions can comprise about 0.1 wt % to about 25 wt % of at least one disodium salt monohydrate of 4-5-dihydroxy-1,3 benzenedisulfonic acid; about 1 wt % to about 90 wt % of particles; and about 10 wt % to about 90 wt % of at least one liquid. The particles can comprise nanoparticulate metals, metal oxides, silica and coated particles. The liquid can comprise at least one polar liquid.04-22-2010

Patent applications by Frank Vito Distefano, Macungie, PA US

James G. Distefano, San Francisco, CA US

Patent application numberDescriptionPublished
20110022054Suture Tensioner with Gauge - A tensioner for a tightening a surgical knot has a squeeze handle and a pair of jaw arms that pivot from a common point behind the handle. The jaw arms have a jaw clamp at the distal tip to clamp onto the suture material, and a release handle at the proximal or butt end. A spreader or distractor mechanism may be a pantographic arrangement of struts joined to anchor points on the jaw arms. This converts axial motion of an actuator rod into a lateral distractive force. A tension gauge in the handle indicates the amount of tension being applied to the suture material.01-27-2011

Michael Vincent Distefano, Martinsville, NJ US

Patent application numberDescriptionPublished
20090271468Complex event processing cloud - A means to establish a CEP Cloud with processing capabilities to scale as required by the business application or applications leveraging the CEP Cloud. Included is a method of establishing a network of CEP Engines that work in concert with each other so to provide CEP Services to deliver the Service Level Agreements (SLA) of function, latency, and throughput as required by the application.10-29-2009

Paul Distefano, North Kingston, RI US

Patent application numberDescriptionPublished
20090143128PROVIDING CENTRALIZED SERVICES TO GAME OPERATORS - Some example embodiments of the present invention address growing demand by lottery customers for expanded gaming options and new gaming concepts. Example embodiments may include methods and systems for providing a shared centralized gaming host which implements software as a service concepts for lottery and other wagering games.06-04-2009

Peter Distefano, Southboro, MA US

Patent application numberDescriptionPublished
20090022694SIRT1 INHIBITION - A method of culturing cells in the presence of a SIRT1 inhibitor is described.01-22-2009
20090264410THERAPEUTIC COMPOUNDS AND USES THEREOF - Compounds of formula (I) are described herein10-22-2009
20090306168SirT Inhibitors That Bind to NAD - Compound of formula (I)12-10-2009

Patent applications by Peter Distefano, Southboro, MA US