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Ding, NY
Bi-Sen Ding, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100285015 | TARGETING RECOMBINANT THERAPEUTICS TO CIRCULATING RED BLOOD CELLS - Fusion proteins comprising a single chain antigen-binding domain (scFv) of a monoclonal antibody, linked to an anti-thrombotic agent, anti-inflammatory agent, or a pro-drug thereof are provided, where the polypeptide binds to a binding site (antigen) expressed on the surface of a red blood cell at a density greater than 5,000 copies per red blood cell. Pharmaceutical compositions comprising these fusion proteins, and methods of delivering an anti-thrombotic agent to the surface of a red blood cell via delivery of these fusion proteins, and methods of treating or preventing thrombosis, tissue ischemia, acute myocardial infarction (AMI), ischemic stroke, cerebrovascular disease, pulmonary embolism, or ischemic peripheral vascular disease via administration of the fusion proteins or compositions comprising same are also provided. | 11-11-2010 |
| 20110262466 | COMPOSITIONS CONTAINING THROMBOMODULIN DOMAINS AND USES THEREOF - Compositions are provided comprising a thrombomodulin domain linked to a targeting moiety that binds to a determinant on the surface of a target endothelial cell or red blood cell, wherein the thrombomodulin domain may be the extracellular domain, the N-terminal lectin-like domain, or an epidermal growth factor (EGF)-like domain. The targeting moiety may be a single chain antigen-binding domain (scFv), and the targeting moiety and thrombomodulin domain of the composition may be linked as a continuous polypeptide chain. Methods of delivery and use of a composition described herein are provided, as well as methods of treating or preventing thrombosis, inflammation, tissue ischemia, sepsis, acute lung injury (ALI), acute myocardial infarction (AMI), ischemic stroke, cerebrovascular disease, pulmonary embolism, or ischemic peripheral vascular disease is provided. | 10-27-2011 |
Chen Ding, Rochester, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090292791 | AUTOMATED CODE SPLITTING AND PRE-FETCHING FOR IMPROVING RESPONSIVENESS OF BROWSER-BASED APPLICATIONS - A “code splitting tool” provides various techniques for automatically analyzing and rewriting existing browser-based applications to introduce dynamic code loading into those applications thereby improving perceived application responsiveness. Structural elements of application code (including functions, classes, etc.) are broken into small “stubs” with corresponding bodies. Rewritten applications then initially transfer only the portion of the code (including some combination of stubs and bodies) to the client as necessary for initial application execution. Additional stubs and/or bodies are then transferred either on-demand at runtime or in the background. Automated code rewriting proceeds without requiring any application-specific knowledge or changes to existing code prior to code rewriting. Further, the code splitting tool can tailor code rewriting to specific computing devices (computers, PDA's, cell phones, etc.), specific network conditions, and/or specific users, through an automated training process that creates clusters that control code downloads to optimize perceived application responsiveness. | 11-26-2009 |
| 20100077153 | Optimal Cache Management Scheme - Computer implemented method, system and computer usable program code for cache management. A cache is provided, wherein the cache is viewed as a sorted array of data elements, wherein a top position of the array is a most recently used position of the array and a bottom position of the array is a least recently used position of the array. A memory access sequence is provided, and a training operation is performed with respect to a memory access of the memory access sequence to determine a type of memory access operation to be performed with respect to the memory access. Responsive to a result of the training operation, a cache replacement operation is performed using the determined memory access operation with respect to the memory access. | 03-25-2010 |
| 20100107142 | SCALABILITY ANALYSIS FOR SERVER SYSTEMS - Described is predicting cache locality in a multicore/multithreaded processing environment including when threads share cache data in a non-uniform interleaving manner. Thread execution traces are analyzed to compute a set of per-thread parameters that can then be used to predict cache miss rates for other cache sizes. In one aspect, a model is based upon a probability that the cache reuse distance will increase because of accesses by other threads, and another probability that the reuse distance will decrease because of intercept accesses by other threads to shared data blocks. Estimates of the number of shared data blocks, possibly shared data blocks and private data blocks are used in the computations. | 04-29-2010 |
Fa-Xiang Ding, Staten Island, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090042926 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment - The present invention encompasses compounds of Formula (I): as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating atherosclerosis, dyslipidemias and the like. Pharmaceutical compositions and methods of use are also included. | 02-12-2009 |
| 20090082340 | 3-SUBSTITUTED-5- AND 6-AMINOALKYL INDOLE-2-CARBOXYLIC ACID AMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I - The present invention discloses and claims methods for the treatment of a patient suffering from a disease or disorder ameliorated by inhibition of casein kinase Iε activity comprising the administration of a compounds of formula (I) and formula (II) | 03-26-2009 |
| 20090170891 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment - The present invention encompasses compounds of Formula I: | 07-02-2009 |
| 20100144778 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment - The present invention encompasses compounds of Formula (I): as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating atherosclerosis, dyslipidemias and the like. Pharmaceutical compositions and methods of use are also included. | 06-10-2010 |
| 20100197691 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT - Compounds of the Formula: (I) as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating hypertension, diabetes, inflammation, atherosclerosis, pain, and the like are disclosed. Pharmaceutical compositions and methods of use are also included. | 08-05-2010 |
| 20110003849 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT - Compounds of the formula: as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating diabetes, inflammation, atherosclerosis, hypertension, pain and the like are disclosed. Pharmaceutical compositions and methods of use are also included. | 01-06-2011 |
Jane Xiaohong Ding, White Plains, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090313262 | SECURING DATA FROM A SHARED DEVICE - A method for securing the use of data on a first device where the data is sent from a second device, the method including registering at least a first application on the first device, starting the at least first application on the first device, transmitting data from the second device to the first device, determining whether the at least first application is registered, determining whether the at least first application is active, granting, based on the determination whether the at least first application is registered and whether the at least first application is active, the at least first application access to the data transmitted from the second device. | 12-17-2009 |
Jienan Ding, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110230894 | SYSTEMS, DEVICES, AND METHODS FOR PROVIDING INSERTABLE ROBOTIC SENSORY AND MANIPULATION PLATFORMS FOR SINGLE PORT SURGERY - The present disclosure relates to systems, devices, and methods for providing foldable, insertable robotic sensory and manipulation platforms for single port surgery. The device is referred to herein as an Insertable Robotic Effector Platform (IREP). The IREP provides a self-deployable insertable device that provides stereo visual feedback upon insertion, implements a backbone structure having a primary backbone and four secondary backbones for each of the robotic arms, and implements a radial expansion mechanism that can separate the robotic arms. All of these elements together provide an anthropomorphic endoscopic device. | 09-22-2011 |
Josh Ding, Painted Post, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100126225 | METHOD FOR HOMOGENIZING A GLASS MELT - An apparatus for homogenizing molten glass is disclosed comprising a stir chamber including a rotatable stirrer disposed therein. The apparatus further comprises a catcher coupled to the stirrer shaft, the catcher having a concave, bowl-like shape and adapted to prevent particulate from falling from upper surfaces of the stir chamber into the molten glass. At least a portion of the catcher bottom is in contact with the upper surface of the molten glass, whereas a peripheral edge of the catcher is preferably raised above the upper surface of the molten glass to prevent molten glass from contacting an upper surface of the catcher. | 05-27-2010 |
Lei Ding, Hawthorne, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20120008819 | OPTIMIZATION OF HUMAN ACTIVITY DETERMINATION FROM VIDEO - In an embodiment, automated analysis of video data for determination of human behavior includes providing a programmable device that segments a video stream into a plurality of discrete individual frame image primitives which are combined into a visual event that may encompass an activity of concern as a function of a hypothesis. The visual event is optimized by setting a binary variable to true or false as a function of one or more constraints. The optimized visual event is processed in view of associated non-video transaction data and the binary variable by associating the optimized visual event with a logged transaction if associable, issuing an alert if the binary variable is true and the optimized visual event is not associable with the logged transaction, and dropping the optimized visual event if the binary variable is false and the optimized visual event is not associable. | 01-12-2012 |
| 20120008836 | SEQUENTIAL EVENT DETECTION FROM VIDEO - Human behavior is determined by sequential event detection by constructing a temporal-event graph with vertices representing adjacent first and second primitive images of a plurality of individual primitive images parsed from a video stream, and also of first and second idle states associated with the respective first and second primitive images. Constructing the graph is a function of an edge set between the adjacent first and second primitive images, and an edge weight set as a function of a discrepancy between computed visual features within regions of interest common to the adjacent first and second primitive images. A human activity event is determined as a function of a shortest distance path of the temporal-event graph vertices. | 01-12-2012 |
Liang Ding, Ithaca, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090099351 | NYLON POLYRIBONUCLEOSIDES - The present invention provides a polyribonucleoside ladder copolymer molecule of general formula (I) | 04-16-2009 |
Maynard Guotsuen Ding, Yorktown Heights, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090317321 | DECOMPOSITION OF SPENT SULFURIC ACID USING OXYGEN - Spent sulfuric acid is decomposed by atomizing it with an oxygen-containing stream into a decomposition furnace. | 12-24-2009 |
Weidong Warren Ding, Orangeburg, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080279874 | COMPOSITIONS AND METHODS FOR MODULATION OF PLK1 KINASE ACTIVITY - Described are compositions and methods for activating a Plk1 protein as well as phospho-specific anti-Myt1 antibodies that can be used to detect phosphorylation of Myt1. Activated Plk1 protein, phospho-specific anti-Myt1 antibodies, and/or Plk1 substrates can be used in screening assays to identify compounds that modulate the ability of Plk1 to phosphorylate and/or bind to a Plk1 substrate. | 11-13-2008 |
Weiqiang Ding, Potsdam, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100313644 | NOVEL CHARACTERIZATION TOOLS FOR TONER ADHESION AND ADHESION DISTRIBUTION - A system, method and device for measuring toner performance by randomly applying a toner sample having toner particles to a substrate, and positioning the substrate such that a force may be applied to individual particles of the measuring toner. A rolling resistance or rotation of the individual particles of the measuring toner is measured. The measurements may be analyzed to determine adhesion and distribution properties of individual toner particles of the measuring toner sample. | 12-16-2010 |
Yidong Ding, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100131306 | SYSTEM AND METHOD FOR CALCULATING AND PROVIDING A PREDETERMINED PAYMENT OBLIGATION - A system and method is provided for calculating and generating a predetermined payment obligation. A hypothetical portfolio of securities is selected having an initial value. A financial instrument is issued that references the hypothetical portfolio, the financial instrument having a fixed term. A guaranteed minimum withdrawal benefit is deducted from a net asset value of the hypothetical portfolio on a periodic basis for the fixed term. The net asset value of the hypothetical portfolio is determined to be zero if the net asset value of the hypothetical portfolio falls below a predetermined amount of funds. An adjustment in the number of securities in the hypothetical portfolio is calculated with a computer on a periodic basis according to an algorithm, the algorithm taking into account at least one of a prevailing market value of the securities in the hypothetical portfolio and a net present value of an obligation to deduct the predetermined amount of funds until the end of the fixed term. At the end of the fixed term, the net asset value of the hypothetical portfolio is paid. | 05-27-2010 |
Zhebo Ding, Niskayuna, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090087381 | CHELATOR-FUNCTIONALIZED NANOPARTICLES - Provided herein are chelator-functionalized nanoparticles comprising a passive core; and an active coating that demonstrate T1 magnetic resonance pattern upon exposure to a magnetic field. Also provided are methods of making such chelator-functionalized nanoparticles as well as imaging methods using the nanoparticles. | 04-02-2009 |
Zhiyong Ding, Valhalla, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110097330 | Novel Gene Disruptions, Compostitions and Methods Relating Thereto - The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO179, PRO181, PRO244, PRO247, PRO269, PRO293, PRO298, PRO339, PRO341, PRO347, PRO531, PRO537, PRO718, PRO773, PRO860, PRO871, PRO872, PRO813, PRO828, PRO1100, PRO1114, PRO115, PRO1126, PRO1133, PRO1154, PRO1185, PRO1194, PRO1287, PRO1291, PRO1293, PRO1310, PRO1312, PRO1335, PRO1339, PRO2155, PRO1356, PRO1385, PRO1412, PRO1487, PRO1758, PRO1779, PRO1785, PRO1889, PRO90318, PRO3434, PRO3579, PRO4322, PRO4343, PRO4347, PRO4403, PRO4976, PRO260, PRO6014, PRO6027, PRO6181, PRO6714, PRO9922, PRO7179, PRO7476, PRO9824, PRO19814, PRO19836, PRO20088, PRO70789, PRO50298, PRO51592, PRO1757, PRO4421, PRO9903, PRO1106, PRO1411, PRO1486, PRO1565, PRO4399 or PRO4404 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities. | 04-28-2011 |
Zhong Ding, Pittsford, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080228319 | ROBOTIC ARM ALIGNMENT - A method for aligning the position of a movable arm includes: providing an alignment element on the apparatus projecting a distance above the apparatus in the z-direction and having a surface lying in a plane formed by an x and y axis; providing a movable arm having a tool at the free end; positioning the object such that the surface of the element faces the tool; moving the tool in a direction towards the surface of the element; sensing when the tool reaches a predetermined point on or above the surface of the element, whereby the position of the tool in the z-direction is determined based on the relationship between the measured response of the tool and the height of the tool above the surface of the alignment element; placing the tool on or at a distance in the z-direction from the surface; moving the tool in the x-direction while sensing the surface of the element; moving the tool in the x-direction until an edge of the element is sensed; determining the center in the x-direction based on the known distance the tool has moved and the known dimensions of the element in the x-direction; placing the tool on or at a distance in the z-direction from the surface; moving the tool in the y-direction while sensing the surface of the element; moving the tool in the y-direction until an edge of the element is sensed; determining the center in the y-direction based on the known distance the tool has moved and the known dimensions of the element in the y-direction. In a preferred embodiment, the tool is a metering probe having a disposable tip on the end thereof. In another preferred embodiment, the measured response is the air pressure in the probe and the metering probe has a source of compressed air for expelling air out of the end of the probe and a pressure transducer for measuring the air pressure inside the metering probe. | 09-18-2008 |
| 20090093065 | ASPIRATING AND DISPENSING SMALL VOLUMES OF LIQUIDS - A metering device for aspirating and dispensing a liquid includes a housing; a pumping medium, preferably a gas containing chamber contained within the housing; a channel having a proximate end in fluid communication with the chamber and a distal end in fluid communication with an external environment; a heat or cold source providing a source of heat or cold to the gas containing chamber; and a temperature sensor for measuring the temperature inside the chamber. In a preferred embodiment, the device further includes a pressure sensor for measuring gas pressure inside the chamber, or multiple chambers. A method for aspirating and dispensing a liquid includes: providing a metering device for aspirating and dispensing a liquid that includes a housing; a gas containing chamber contained within the housing, the chamber; a channel having a proximate end in fluid communication with the chamber and a distal end in fluid communication with an external environment; a heat or cold source providing a source of heat or cold to the gas containing chamber; and a temperature sensor for measuring the temperature inside the chamber; providing a source of liquid to be aspirated; bringing the distal end of the channel into contact with the liquid; cooling the gas containing chamber with the heat or cold source to aspirate a first volume of liquid into the device; and heating the gas containing chamber to dispense a second volume of liquid out of the device. In a preferred embodiment, the metering device is a used in a diagnostic analyzer for determining the presence of one or more analytes in a sample. | 04-09-2009 |
| 20090233310 | PARTICLE AGGLUTINATION IN A TIP - An apparatus and a related method for performing particle agglutination reactions in a single, disposable probe tip are disclosed. The probe tip includes a sample cavity for sample acquisition, at least one flanking cavity for the capture of particles by centrifugation or other means, a transition zone for the mixing of the sample with reagents for agglutination and a detection zone for the optical detection of particle agglutination. A mechanism may be attached to the probe tip for the controlled movement of fluids through the internal volume of the probe tip. The probe tip is particularly useful for the automation of high-throughput agglutination-type assays. | 09-17-2009 |
| 20100221757 | PATIENT SAMPLE CLASSIFICATION BASED UPON LOW ANGLE LIGHT SCATTERING - An apparatus for classifying a liquid patient sample includes at least one sample container having a quantity of a sample that is aggressively acted upon so as to create a flow field. A measurement mechanism includes at least one low angle light emitter aligned with a measurement window of the at leas tone sample container and a detector oppositely disposed relative to the measurement window. Measurement of the scattered light detects particle characteristics of a moving flow field from the sample to determine, for example, the amount of agglutination of the sample so as to perform blood typing or other classifications without spatial separation. | 09-02-2010 |
| 20110070600 | PARTICLE AGGLUTINATION IN A TIP - An apparatus and a related method for performing particle agglutination reactions in at least one disposable probe tip are disclosed. The at least one probe tip includes a sample cavity for sample acquisition, at least one flanking cavity for the capture of particles by centrifugation or other means, a transition zone for the mixing of the sample with reagents for agglutination and a detection zone for the optical detection of particle agglutination. A mechanism may be attached to the probe tip for the controlled movement of fluids through the internal volume of the probe tip. The probe tip is particularly useful for the automation of high-throughput agglutination-type assays. | 03-24-2011 |
| 20110252872 | METHOD FOR ESTIMATING VISCOSITY - A method for estimating the viscosity of a liquid in an aspirating or dispensing probe, includes: measuring a reference pressure which is the pressure inside a metering tip when no dispense or aspirate is occurring (P | 10-20-2011 |