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Dineva

Magda Anastassova Dineva, Cambridgeshire GB

Patent application numberDescriptionPublished
20100136542NUCLEIC ACID AMPLIFICATION AND TESTING - Methods for amplifying a target nucleic acid by self-sustained amplification methods are described. The methods are designed, in particular, to be carried out without use of specialised lab facilities or instruments. Compositions, lyophilised formulations, and kits for carrying out the methods are also described.06-03-2010

Magda Anastassova Dineva, Cambridge GB

Patent application numberDescriptionPublished
20080206853SIGNAL ENHANCEMENT SYSTEM WITH MULTIPLE LABELED-MOIETIES - Dipstick tests for detecting analyte are described. In a preferred embodiment, a multiple biotinylated antibody capable of binding analyte is bound to an anti-biotin antibody labeled with colloidal gold and wicked up the dipstick with test solution thought to contain analyte. Complex formed between analyte, biotinylated anti-analyte antibody, and colloidal gold labeled anti-biotin antibody is captured at a capture zone of the dipstick. Presence of colloidal gold label at the capture zone indicates the presence of analyte in the test solution. The sensitivity of analyte detection using such methods is an order of magnitude higher than for comparable methods in which biotinylated anti-analyte antibody bound to analyte is wicked up the dipstick in a first step, and a colloidal gold labeled anti-biotin antibody is wicked up the dipstick in a separate step. Kits for performing the tests of the invention are also described.08-28-2008

Patent applications by Magda Anastassova Dineva, Cambridge GB

Magda Anastossova Dineva, Cambridgeshire GB

Patent application numberDescriptionPublished
20100028204DEVICE, SYSTEM AND METHOD FOR PROCESSING A SAMPLE - A device for the processing of a sample comprises a location apparatus, a processing chamber for receiving the sample and a plurality of reagent chambers. The reagent chambers have openings defined in the location apparatus. The processing chamber is movable relative to the reagent chambers to enable sequential communication with each reagent chamber in turn.02-04-2010