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Dinauer

David Dinauer, Brown Deer, WI US

Patent application numberDescriptionPublished
20090069190METHODS FOR HLA TYPING - The present invention relates to methods for reducing the ambiguity in human leukocyte antigen (HLA) allele identification. In particular, the methods comprise using target specific oligonucleotide (TSO) techniques to determine a first set of possible HLA alleles. The methods further comprise using sequence-based typing (SBT) to obtain a second set of possible HLA alleles. The two sets of the possible HLA alleles are then combined to determine at least one common allele identified in the both the TSO and SBT assays, thus reducing the ambiguity associated with current HLA typing procedures.03-12-2009
20090143995System and Method for Management and Evaluation of Genotyping Data - Provided are systems and methods for improving efficiency in high throughput genotyping operations by implementing a unique workflow management architecture that permits faster and more accurate determination and evaluation of genotyping and haplotyping, and software to accomplish the same. The system provides a user with a highly-accurate summary and multiple-field breakdown of panels of genotyping data samples for batch approval and batch selection of ambiguous or potentially unique sample sets which can be selected for further analysis. Also provided are tools for evaluating and improving the operation of a genotyping laboratory to maximize the testing and typing of the significant quantities of raw data used in genotyping that are produced in high-throughput laboratory environments.06-04-2009

David Dinauer, Fox Point, WI US

Patent application numberDescriptionPublished
20080280289Primers, Methods and Kits for Detecting Killer-Cell Immunoglobulin-Like Receptor Alleles - Embodiments of the present invention describe primer pairs, methods and kits for identifying and/or detecting killer-cell immunoglobulin-like receptor (KIR) alleles. The present primer sets include one or more primer pairs that can produce amplicons specific for an individual KIR allele and that are less than 1000 bp in size. Additionally, the primer sets can target intra-exon and/or extracellular domains of KIR alleles for amplification.11-13-2008

Violeta Dinauer, San Diego, CA US

Patent application numberDescriptionPublished
20080293920Arginine Analogs, and Methods for Their Synthesis and Use - The present invention relates to novel arginine analogs, and methods for their synthesis and use. Such analogs are designed to provide a protected or free thiol (—SH) group, thereby providing a convenient linkage chemistry for coupling to a suitable group on a target such as a protein, polypeptide, detectable label or solid phase, and at a site distal to the guanidino group. Arginine analog conjugates are useful for generating antibodies that can bind specifically with dimethylarginine, which can be detected using such antibodies in immunoassays.11-27-2008

William Dinauer, Hudson, WI US

Patent application numberDescriptionPublished
20090173428Precision Lamination of Multilayered Structures - This document describes the methodology for laminating layers of converted materials to form a precision laminated multilayered structure. With this methodology the pattern in the next layer to be laminated to create the multilayered structure can be adjusted based upon first or prior layer that the next layer is to be laminated to. The next layer will then be precisely aligned to the first or prior layers creating a precision laminated multilayer structure.07-09-2009
20110080476High Performance Vision System for Part Registration - An embodiment describes a vision system capable of inspecting large areas with high accuracy and speed. According to embodiments, a more sophisticated system is used that allows the camera to see the entire workpiece surface. Prior art devices used cameras with a fixed field-of-view. This causes problems with finding parts accurately all over the field, especially when their locations are not known or they exist outside of the fixed field-of-view of a camera. An embodiment uses our scanner scheme described in detail above that can find fiducial marks accurately over the entire workpiece.) A calibration is used to correct for perspective distortions that occur from viewing the fiducial marks from the skewed angles. The calibration also corrects for various errors in several possible optical configurations.04-07-2011