Patent application number | Description | Published |
20090303584 | METHOD FOR LASER SCANNING MICROSCOPY AND BEAM COMBINER - A method for laser scanning microscopy is characterized by the use of encapsulated fiber multiplexers from the telecommunications field for combining the beams of a plurality of lasers of different wavelengths and coupling them together into a laser scanning microscope and by corresponding beam combiners. Light-conducting guides to which different lasers can be coupled, preferably by light guides, are advantageously guided out of an encapsulated component. | 12-10-2009 |
20100027108 | CONFOCAL LASER MICROSCOPE - A confocal laser microscope has at least one laser whose illumination light is transmitted in direction of the microscope objective by at least one light-conducting fiber. The light-conducting fiber can be plugged in at a housing which preferably comprises the scanning head of the microscope, and a holder is provided which can be plugged into the housing and into which the light-conducting fiber projects and which is provided at its end remote of the fiber with first optics for transmitting the laser light exiting divergently from the fiber in direction of at least partially displaceable collimating optics in the housing. At least second optics are advantageously arranged between the first optics and the collimating optics. | 02-04-2010 |
20100214653 | MICROSCOPE HAVING INTERNAL FOCUSING - The invention relates to a laser scanning microscope with a scanner and a microscope objective, and to a control method for such a microscope. In order to obtain sharp imaging of the sample in a laser scanning microscope, the distance between the microscope objective and the sample is usually varied for adjusting the focus position. However, relative movements between the objective and the sample can be problematic. In view of the costly special objective, internal focusing of the objective is a disadvantageous solution. An improved laser scanning microscope should make it possible to sharply image a sample with standard objectives without relative movement between the microscope objective and sample. According to the invention, a tube lens is provided which is displaceable along the optical axis, and the focus position is adjustable relative to a front optical element of the microscope objective by adjusting the tube lens. | 08-26-2010 |
20100254000 | MIRROR CASCADE FOR BUNDLING A PLURALITY OF LIGHT SOURCES AND A LASER-SCANNING MICROSCOPE - A mirror cascade for the adjustment-free bundling of a plurality of light sources to be coupled into the beam path of a laser scanning microscope, comprising a beam combiner housing in which the mirror cascade is located, wherein the beam combiner housing can be either mounted directly on a scanning head of a laser scanning microscope and has a direct optical connection thereto or can be mounted on a microscope housing and has an optical connection thereto or is directly arranged in the scanning head. The invention further relates to a laser scanning microscope with such a mirror cascade. | 10-07-2010 |
20110051234 | LASER SCANNING MICROSCOPE HAVING VARIABLE LIGHT INTENSITY AND CONTROL METHOD FOR THE SAME - A laser scanning microscope (LSM) having variable light intensity and a control method for the same. The light intensity of a laser beam in an LSM has been controlled to date with high accuracy, but also high costs by means of an acousto-optic component (AOM, AOTF). According to the invention, such a component for beam modulation is to be omitted, without reducing the exposure accuracy of the sample. In an LSM, a directly modulated laser diode ( | 03-03-2011 |
20110096386 | LASER SCANNING MICROSCOPE HAVING A LASER DIODE COMPRISING A LIGHT MODULATION DEVICE - The invention makes it possible to adjust the light intensity of a laser scanning microscope laser beam in an economical manner and with high accuracy. A separate acousto-optic component can be omitted in that a light modulation section such as an electroabsorption modulator (EAM) or a semiconductor amplifier (SOA) is arranged directly at the laser diode, advisably at one of its front sides. It is nevertheless possible to control the light intensity economically and with high accuracy because the important parameters of the laser beam remain unchanged when the optical output power is changed by the light modulation section. The light modulation section is preferably formed integral with the laser diode in at least one material layer. | 04-28-2011 |
20120229815 | LASER SCANNING MICROSCOPE AND METHOD FOR OPERATION THEREOF - Laser scanning microscope and method for the operation thereof having at least two detection channels which has at least one beamsplitter with a splitting of the sample light deviating from the 50:50 split and/or, with 50:50 split in the detection channels, has detectors with differently adjusted gain, or in at least one detection channel with equal light splitting has an additional light attenuator. | 09-13-2012 |
20120229879 | MIRROR CASCADE FOR BUNDLING A PLURALITY OF LIGHT SOURCES AND A LASER-SCANNING MICROSCOPE - A mirror cascade for the adjustment-free bundling of a plurality of light sources to be coupled into the beam path of a laser scanning microscope, comprising a beam combiner housing in which the mirror cascade is located, wherein the beam combiner housing can be either mounted directly on a scanning head of a laser scanning microscope and has a direct optical connection thereto or can be mounted on a microscope housing and has an optical connection thereto or is directly arranged in the scanning head. The invention further relates to a laser scanning microscope with such a mirror cascade. | 09-13-2012 |
20150077843 | HIGH-RESOLUTION SCANNING MICROSCOPY - A microscope and method for high resolution scanning microscopy of a sample, having: an illumination device for the purpose of illuminating the sample, an imaging device for the purpose of scanning at least one point or linear spot over the sample and of imaging the point or linear spot into a diffraction-limited, static single image below an imaging scale in a detection plane. A detector device is used for the purpose of detecting the single image in the detection plane for various scan positions, with a location accuracy which, taking into account the imaging scale in at least one dimension/measurement, is at least twice as high as a full width at half maximum of the diffraction-limited single image. A non-imaging redistribution element is arranged in front of a detector array of the detector and which distributes the radiation from the detection plane onto the pixels of the detector array in a non-imaging manner, and the redistribution element comprises a bundle of optical fibers. | 03-19-2015 |