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Diel
Mark Diel, Menlo Park, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100030010 | HANDHELD RADIATION DELIVERY SYSTEM - A handheld radiation delivery system is disclosed that includes a two-part delivery module comprising a reusable portion that contains a radioactive source wire and a disposable portion that includes a drive assembly for moving the radioactive source wire between storage and treatment positions. A disposable applicator tip is provided that includes a cannula for receiving the radioactive source wire when in the treatment position and a mechanism for limiting the number of uses of the device. A handheld cable actuator is operatively connected to the disposable portion of the handpiece to impart motion to the source wire. | 02-04-2010 |
Patrick Diel, Koln DE
| Patent application number | Description | Published |
|---|---|---|
| 20110178052 | 9-ALPHA ESTRATRIENE DERIVATIVES AS ER-BETA SELECTIVE LIGANDS FOR THE PREVENTION AND TREATMENT OF INTESTINAL CANCER - Use of 9α-estra-1,3,5(10)-triene derivatives of formula (I) | 07-21-2011 |
Patrick Diel, Pullheim DE
| Patent application number | Description | Published |
|---|---|---|
| 20110256579 | Method for Verifying and/or Identifying Hormonally Effective Substances - The invention relates to a method for verifying and/or identifying hormonally effective substances using the pheromone system of yeast, to yeast cells for carrying out the method, and to the use thereof. The method according to the invention comprises the following steps: a) adding yeast culture medium or buffer to a sample which presumably contains a hormonally effective substance, b) thereafter contacting the sample with haploid yeast cells that possess features 1 through 3: 1. the DNA sequence coded for a heterologous hormone receptor is placed under the control of a constitutive promoter, 2. the DNA sequence coded for a yeast pheromone is placed under the control of a promoter that can be regulated by the hormone receptor, 3. a gene that is coded for a receptor for the yeast pheromone is constitutively expressed, wherein the activation of the hormone receptor by the hormonally effective substance leads to the expression and secretion of the yeast pheromone, and c) the physiological and/or morphological changes of haploid yeast cells are detected. | 10-20-2011 |