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Di Marzo

Maria Di Marzo, Santa Maria A Vico IT

Patent application numberDescriptionPublished
20100184972SYNTHESIS OF DEOXYBIOTINYL HEXAMETHYLENEDIAMINE-DOTA - A process for the synthesis of deoxybiotinyl hexamethylenediamine0-DOTA is herein described. Said process comprises reacting biotinyl hexamithylenediamine with tri-t-butyl DOTA in the presence of benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate, as the condensing agent, and triethylamine, as a base.07-22-2010

Maria Di Marzo, Santa Maria A Vico Casera IT

Patent application numberDescriptionPublished
20080207729Indole Derivatives Having Antitumor Activity - Indole derivatives of Formula (I+A) having antitumour and chemosensitizing activity are described. Also described are pharmaceutical compositions containing the above-mentioned compounds, for the treatment of tumours.08-28-2008

Vincenzo Di Marzo, Pozzuoli IT

Patent application numberDescriptionPublished
20100249223NEW USE FOR CANNABINOID-CONTAINING PLANT EXTRACTS - The present invention relates to the use of cannabinoid-containing plant extracts in the prevention or treatment of diseases or conditions that are alleviated by blockade of one or more types of TRP channel. Preferably the subset of TRP channel that is blockaded is the TRPA channel. More preferably the TRPA channel is the TRPA1 channel. Preferably the diseases or conditions to be prevented or treated include: neuropathic pain, inflammation or vasoconstriction. Alternatively the TRP channel that is blockaded is the TRPM channel. More preferably the TRPM channel is the TRPM8 channel. Preferably the diseases or conditions to be prevented or treated are cancer. More preferably the cancers to be treated include: cancer of the prostate, cancer of the breast, cancer of the colon, cancer of the lung or cancer of the skin. Alternatively the TRP channel that is blockaded is the TRPV channel. More preferably the TRPV channel is the TRPV1 channel. Preferably the diseases or conditions to be prevented or treated include neuropathic pain, inflammation or vasoconstriction.09-30-2010

Patent applications by Vincenzo Di Marzo, Pozzuoli IT

Vincenzo Di Marzo, Siena IT

Patent application numberDescriptionPublished
20090043129POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS - The present invention relates to high affinity compounds, able to bind CB02-12-2009

Vincenzo Di Marzo, Pozzuoli (napoli) IT

Patent application numberDescriptionPublished
20110288037Pharmaceutical Composition for the Treatment of Pathologies Caused by the General Response of the Immune System - The present invention relates to a pharmaceutical composition consisting of amides of mono- and di-carboxylic acids and hydroxystilbenes, and may be used for the treatment of pathologies caused, sustained and/or characterised by an abnormal general response of the immune system, in both humans and animals.11-24-2011

Vincenzo Di Marzo, Napoli IT

Patent application numberDescriptionPublished
20120115808PHARMACOLOGICAL PREPARATION FOR TOPICAL USE CONTAINING N-PALMITOYL-VANILLAMIDE - The present invention relates to topical preparations containing N-palmitoyl-vanillamide having hyperalgesic activity. In particular, the invention relates to N-palmitoyl-vanillamide for use in the treatment of pathologies selected from: post-herpetic neuralgia, neuralgia of trigeminus, occipital neuralgia, dental neuralgia, glottopharyngeal neuralgia, uremic neuralgia, diabetic neuralgia, headache of different origin, neuropathic itch, neurogenic itch, uremic itch, vulvodinia, vulvar vestibulitis, ano-rectal pain and itch, balano-preputial pain and itch, painful urogenital disorders of dogs and cats, psoriasis-associated pruritus and pain, itching skin diseases (e.g. atopic dermatitis) in the human and veterinary field, muscular pain, pain of the tendon, osteoarthritis associated pain in humans, dogs and cats; painful eye diseases in the human and veterinary field, inflammatory pathologies of the oral cavity in the human and veterinary field.05-10-2012