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Di Bartolomeo

Antonio Di Bartolomeo, Fisciano IT

Patent application numberDescriptionPublished
20110210415FREESTANDING CARBON NANOTUBE NETWORKS BASED TEMPERATURE SENSOR - The present invention introduces a small-size temperature sensor, which exploits a random or oriented network of un-functionalized, single or multi-walled, carbon nanotubes to monitor a wide range of temperatures. Such network is manufactured in the form of freestanding thin film with an electric conductance proven to be a monotonic function of the temperature, above 4.2 K. Said carbon nanotube film is wire-connected to a high precision source-measurement unit, which measures its electric conductance by a standard two or four-probe technique. Said temperature sensor has a low power consumption, an excellent stability and durability, a high sensitivity and a fast response; its manufacturing method is simple and robust and yields low-cost devices. Said temperature sensor, freely scalable in dimension, is suitable for local accurate measurements of rapidly and widely changing temperatures, while introducing a negligible disturb to the measurement environment.09-01-2011

Joseph Di Bartolomeo, Santa Barbara, CA US

Patent application numberDescriptionPublished
20090017098COMPOSITION AND METHOD FOR THE PREVENTION AND RELIEF OF THE SYMPTOMS OF AN INCOMPETENT OR PATULOUS EUSTACHIAN TUBE - A composition and methods for the treatment of symptoms due to disorders, disease or trauma that impairs normal function of die Eustachian tube and alters vital structures or tissues of the middle ear. This includes diseases and disorders of the Eustachian tube altered by tubal incompetence, inflammatory phenomenon as rhinitis, nasal allergies, infections by microorganisms, tympanic membrane rupture or trauma and variants. The composition is comprised of solution including L-Ascorbic acid and a pharmaceutically acceptable liquid carrier and delivery system. The administration of which is applied topically in appropriate composition and dosage for intranasal or trans tympanic route in the form of drops, spray, aerosol, rinse, douche, gel, or devices.01-15-2009
20090197946COMPOSITION AND METHOD FOR TREATMENT OF INFLAMATION AND INFECTIONS OF THE GENITALIA, CONTRACEPTIVE AND THE PROPHYLAXIS OF SEXUALLY TRANSMITTED DISEASES - A composition, employed topically for its microbicidal, spermatocidal activity upon application to the human genitalia and/or anorectal area, and the prophylaxis of sexually transmitted diseases, contraception, and the relief from symptoms of local inflamation and infection. The embodiment incorporates L-Ascorbic acid in a concentration of about 2% to about 25% wt/vol, within an acidic range or pH level of about 4.0 to 2.0 pH respectively, in an aqueous solution with a pharmaceutically acceptable liquid carrier. In alternative exemplary embodiments the composition is in a specified physical state and predetermined composition for the desired therapeutic effect. Additionally, the composition in alternative embodiment includes a synergistic antioxidant and further incorporates enhancing bioactive ingredients. The method for topical application of the composition includes douche, rinse, cream, gel, suppository, saturated tampon and externally saturated condom for treatment of the vagina; drops, spray, cleansing wipe, cream, gel and internally saturated condom for treatment of the penis; and cleansing wipe, gel, suppository and externally saturated condom for male genitalia and rectum.08-06-2009
20100247694COMPOSITION AND METHOD FOR TREAMENT OF INFLAMATION AND INFECTIONS OF THE OUTER EAR CANAL, NOSE AND PARANASAL SINUSES - A composition for topical application to the human external ear canal and nasal membranes for relief from symptoms of inflamation and infections and prophylaxis of sexually transmitted diseases the incoporates L-Ascorbic acid in a concentration of about 2% to about 25% wt/vol., within an acidic range or pH level of about 4.0 to 2.0 pH respectively, in an aqueous solution with a pharmaceutically acceptable liquid carrier. The liquid carrier in alternative exemplary embodiments is pure distilled water or normal 0.9% physiologic saline, pH adjusted in a pre determined composition for the desired therapeutic effect. The liquid carrier in alternative exemplary embodiments is pure distilled water or normal 0.9% physiologic saline, depending upon the preferred degree of absorption and bioavailability to the host tissues of the active ingredients in the novel invention. This may include sodium chloride as the preferred Sea Salt—which by analysis contains 99% sodium chloride and calcium, magnesium, sulphate, iron, and copper minerals. Additionally, the composition in alternative embodiment includes a synergistic antioxidant and further incorporates zinc gluconate in certain embodiments. The method for topical application of the composition includes drops, a rinse, cream, gel or saturated wick.09-30-2010

Sabrina Di Bartolomeo, Roma IT

Patent application numberDescriptionPublished
20110281804PEPTIDIC AND PEPTIDOMIMETIC COMPOUNDS FOR REGULATING AUTOPHAGY - The present invention relates to peptides, peptidomimetic compounds and pharmaceutical uses thereof for the treatment of neurodegenerative diseases or tumourigenesis and more specifically diseases deriving from the dysregulation of the signalling system of Ambra-1-mediated autophagy.11-17-2011