Patent application number | Description | Published |
20090105127 | Methods for stabilizing corneal tissue - Methods of stabilizing collagen fibrils in a cornea are disclosed. The stabilization may be effected by treating the cornea with a protein that crosslinks collagen fibrils, such as decorin. The stablization methods include treatment of corneas before, during, or after a surgical procedure, treatment of keratectasia, and treatment of keratoconus. | 04-23-2009 |
20110060267 | ULTRAVIOLET IRRADIATION TO TREAT CORNEAL WEAKNESS DISORDERS - Methods of strengthening the biomechanical properties of the cornea by exposing the cornea to ultraviolet light in the presence of a photoinitiator are described. These methods can be used to treat keratoconus. They can also be used to treat ectasia following a surgical procedure, or to strengthen the cornea prior to a surgical procedure. | 03-10-2011 |
20110086802 | METHODS TO INCREASE PERMEABILITY OF CORNEAL EPITHELIUM AND DESTABILIZE STROMAL COLLAGEN FIBRIL NETWORK - Methods of increasing the permeability of corneal epithelium to facilitate the diffusion of agents into the collagen fibrillar network of the stroma are provided. Used in combination, these methods open the epithelium to facilitate diffusion of stabilization molecules into the stroma and dissociate bridging molecules from stromal collagen fibers, thereby priming the collagen fibrillar network for restabilization by stabilization molecules. These methods can be used to increase the effectiveness and longevity of non-invasive corneal reshaping, such as orthokeratology, for correcting myopia, hyperopia and astigmatism. | 04-14-2011 |
20130303973 | DRUG STORAGE AND DELIVERY DEVICE AND METHOD - A drug delivery device and method is disclosed. The drug delivery device may include a cutting portion configured to form a slit in a portion of eye tissue. The drug device may also include a sliding assembly configured to slide with respect to the cutting portion to deliver a biopharmaceutical device to the portion of eye tissue. | 11-14-2013 |
Patent application number | Description | Published |
20120057121 | ORTHOKERATOLOGY LENS WEAR COMBINED WITH CHEMICAL TREATMENT TO CORRECT MYOPIA, HYPEROPIA OR ASTIGMATISM - Methods of treating a refractive error of the eye are disclosed comprising applying a treatment that induces swelling of the corneal tissue and applying an orthokeratology lens configured to correct the refractive error that provides a controlled distribution of the corneal tissue. | 03-08-2012 |
20130045926 | COMPOSITION AND METHODS FOR THE PREVENTION AND TREATMENT OF MACULAR DEGENERATION, DIABETIC RETINOPATHY, AND DIABETIC MACULAR EDEMA - Methods of stabilizing and organizing collagen fibrils in extracellular matrix of retinal tissues, particularly Bruch's membranes, and stabilizing retinal pigment epithelial layers lining Bruch's membrane are disclosed. The stabilization and organization may be effected by treating retinal tissues with a protein that crosslinks and organizes collagen fibrils, such as decorin. The stabilization and organization methods include treatment of retinal tissues before, during, or after diagnosis of dry macular degeneration, diagnosis of early stages of diabetic retinopathy and diabetic macular edema to prevent, retard, or limit progression of disorganization of Bruch's membrane and disorganization of retinal pigment epithelial cells lining Bruch's membrane. | 02-21-2013 |
20130129807 | COLLAGEN-BASED IMPLANTS FOR SUSTAINED DELIVERY OF DRUGS - The disclosure provides collagen-based constructs for use in drug delivery. | 05-23-2013 |
20130144260 | DEVICE AND METHOD FOR THE CONTROLLED DELIVERY OF OPHTHALMIC SOLUTIONS - The present disclosure is directed to an injector device for delivering an ophthalmic solution to a cornea of an eye. The device may include a base configured to contact part of the eye, and a needle connected to the base, wherein needle may deliver the ophthalmic solution to the cornea. | 06-06-2013 |
Patent application number | Description | Published |
20090313278 | Database Data Dictionary - Systems and methods are provided a for manipulating data sets. In accordance with one implementation, a computerized system is provided storing, managing, indexing, interrelating, and/or retrieving data sets in a manner independent of the data model. The system includes an element module configured to store and uniquely identify elements and an element relation module configured to store relationships between the elements in the element module. The computerized system may also comprise a class module configured to store attributes of elements in a class and a type definition module configured to define the class and the attributes related to the class. The computerized system may further comprise a state machine module, the state machine module including a state machine transition module and a status module. | 12-17-2009 |
20110295900 | Database data dictionary - Systems and methods are provided for manipulating data sets. In accordance with one implementation, a computerized system is provided for storing, managing, indexing, interrelating, and/or retrieving data sets in a manner independent of the data model. The system includes an element module configured to store and uniquely identify elements and an element relation module configured to store relationships between the elements in the element module. The computerized system may also comprise a class module configured to store attributes of elements in a class and a type definition module configured to define the class and the attributes related to the class. The computerized system may further comprise a state machine module, the state machine module including a state machine transition module and a status module. | 12-01-2011 |
20110295911 | Database data dictionary - Systems and methods are provided for manipulating data sets. In accordance with one implementation, a computerized system is provided for storing, managing, indexing, interrelating, and/or retrieving data sets in a manner independent of the data model. The system includes an element module configured to store and uniquely identify elements and an element relation module configured to store relationships between the elements in the element module. The computerized system may also comprise a class module configured to store attributes of elements in a class and a type definition module configured to define the class and the attributes related to the class. The computerized system may further comprise a state machine module, the state machine module including a state machine transition module and a status module. | 12-01-2011 |
20120317118 | DATABASE DATA DICTIONARY - Systems and methods are provided for manipulating data sets. In accordance with one implementation, a computerized system is provided for storing, managing, indexing, interrelating, and/or retrieving data sets in a manner independent of the data model. The system includes an element module configured to store and uniquely identify elements and an element relation module configured to store relationships between the elements in the element module. The computerized system may also comprise a class module configured to store attributes of elements in a class and a type definition module configured to define the class and the attributes related to the class. The computerized system may further comprise a state machine module, the state machine module including a state machine transition module and a status module. | 12-13-2012 |