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Bruce Der, Vancover CA
| Patent application number | Description | Published |
|---|---|---|
| 20110306807 | METHANOL PURIFICATION METHOD AND APPARATUS - The invention relates to a method and apparatus to recover and purify methanol from gases produced in the digester during the kraft pulping process. The gas is typically recovered as a foul gas (called stripper off gas or SOG) comprising methanol, water and various other contaminants. The gas is then treated with successive decanting and distillation steps to remove impurities, thereby producing highly purified methanol. | 12-15-2011 |
Channing J. Der, Chapel Hill, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20110027806 | FARNESYLTRANSFERASE INHIBITORS FOR TREATMENT OF LAMINOPATHIES, CELLULAR AGING AND ATHEROSCLEROSIS - Although it can be farnesylated, the mutant lamin A protein expressed in Hutchinson Gilford Progeria Syndrome (HGPS) cannot be defarnesylated because the characteristic mutation causes deletion of a cleavage site necessary for binding the protease ZMPSTE24 and effecting defarnesylation. The result is an aberrant farnesylated protein (called “progerin”) that alters normal lamin A function as a dominant negative, as well as assuming its own aberrant function through its association with the nuclear membrane. The retention of farnesylation, and potentially other abnormal properties of progerin and other abnormal lamin gene protein products, produces disease. Farnesyltransferase inhibitors (FTIs) (both direct effectors and indirect inhibitors) will inhibit the formation of progerin, cause a decrease in lamin A protein, and/or an increase prelamin A protein. Decreasing the amount of aberrant protein improves cellular effects caused by and progerin expression. Similarly, treatment with FTIs should improve disease status in progeria and other laminopathies. In addition, elements of atherosclerosis and aging in non-laminopathy individuals will improve after treatment with farnesyltransferase inhibitors. | 02-03-2011 |
Channing Joseph Der, Chapel Hill, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090170837 | METHODS FOR TREATING RAS DRIVEN CANCER IN A SUBJECT - The invention relates to the discovery that the dibenzodiazepinone analogues have growth inhibiting activities on tumorigenic cells that are driven by expression of RAS or mutated RAS. Thus the invention includes methods for inhibiting the activity of RAS using dibenzodiazepinone analogues; methods for inhibiting the growth of a RAS driven cancer cell using dibenzodiazepinone analogues; methods for inhibiting the growth of a RAS driven cancer using dibenzodiazepinone analogues; and methods for treating a subject having a RAS driven cancer using dibenzodiazepinone analogues. | 07-02-2009 |
Harry Der, Westford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110213905 | COMMUNICATION PROTOCOL FOR CONTROLLING TRANSFER OF TEMPORAL DATA OVER A BUS BETWEEN DEVICES IN SYNCHRONIZATION WITH A PERIODIC REFERENCE SIGNAL - A communication protocol over the serial bus allows a peripheral device to control the flow of data between a host computer and the peripheral device so as to maintain synchronization to a periodic reference signal. The protocol involves transferring flow control messages between the peripheral device and the host computer, allowing the peripheral device to control how and when the host computer sends the uncompressed audio and video data. | 09-01-2011 |
Joseph Der, Brooklyn, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100175353 | Magnetic Riding Shoe and Stirrup - A contact system for a horse back rider allows a rider to maintain contact between their boot and the stirrup of a saddle while riding. The rider wears magnetic footwear such as a riding boot with an affixed magnet. The stirrup has a contact patch that includes a plate of ferrous metal or another magnet oriented such that it attracts the magnetic footwear. The contact patch is positioned such that it will be proximate to the magnet in the footwear when riding. During normal riding maneuvers, magnetic attractive forces between the footwear and the contact patch will maintain contact between the rider's feet and the stirrup. However, if the rider falls, the magnetic attractive forces do not bind the rider's feet to the stirrup. | 07-15-2010 |
Keniv G. Der, Palo Alto, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110302285 | UPDATE SERVER TO UPDATE RENDERED CONTENT - A method includes maintaining a list of component dependencies for components of a plurality of webpages served from a web server. A change relating to a data item in a database is detected. A first set of components that are impacted by the change relating to the data item in the database are identified. Using the list of component dependencies, a second set of components that are dependent on the first set of components are identified. A set of webpages, served from the web server to at least one browser application, that include components from the first and second sets of components are identified. From an update server, an update operation is initiated with respect to the set of webpages. | 12-08-2011 |
Kevin G. Der, Palo Alto, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110302216 | METHODS AND SYSTEMS FOR MERGING TOPICS ASSIGNED TO CONTENT ITEMS IN AN ONLINE APPLICATION - A question-and-answer application having questions with which topics are associated is described. In some embodiments, user-generated topics are assigned to questions to indicate the subject matter covered by the questions. The application logic includes topic merge logic for quickly and efficiently merging two topics, while enabling the topic merge operation to be easily undone if necessary. | 12-08-2011 |
| 20110302485 | COMPONENT-BASED CONTENT RENDERING SYSTEM - A method to perform component-based rendering of a webpage includes identifying a component hierarchy from which to render the webpage. A set of components are selected from the component hierarchy as an evaluation component set. The evaluation component set is evaluated by determining that a particular component of the evaluation component set does not include a data request for data item to be used in the rendering of the webpage. Responsive to the determination, least one child component of the particular component is identified within the component hierarchy. The child component is added to the evaluation component set. | 12-08-2011 |
Lawrence Der, Austin, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100009645 | Controlling Fine Frequency Changes In An Oscillator - In one embodiment, the present invention includes a method for determining if a frequency control instruction would cause a first capacitor bank to reach a limit and adjusting the first capacitor bank in a first direction using a calibration value and adjusting a second capacitor bank in a second direction if the first capacitor bank would reach the limit. Furthermore, the calibration value may be calculated and stored in accordance with other embodiments. In such manner, small changes in capacitance and correspondingly small changes in frequency may be effected. | 01-14-2010 |
Sandy D. Der, Toronto CA
| Patent application number | Description | Published |
|---|---|---|
| 20090291448 | Prognostic and Predictive Gene Signature for Non-Small Cell Lung Cancer and Adjuvant Chemotherapy - The application provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups and for determining the benefit of adjuvant chemotherapy by way of a multigene signature. The application also includes kits and computer products for use in the methods of the application. | 11-26-2009 |
| 20100184063 | PROGNOSTIC AND PREDICTIVE GENE SIGNATURE FOR NON-SMALL CELL LUNG CANCER AND ADJUVANT CHEMOTHERAPY - The application provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups and for determining the benefit of adjuvant chemotherapy by way of a multigene signature. The application also includes kits and computer products for use in the methods of the application. | 07-22-2010 |
Sherman Der, Redmond, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20100153486 | TECHNIQUES TO AUTOMATICALLY SYNDICATE CONTENT OVER A NETWORK - Techniques to automatically syndicate content over a network are described. An apparatus may comprise a client computer having a processing system with a processor and computer-readable medium. The computer readable medium may store program instructions for a syndication manager component communicatively coupled to a content producing component arranged to be executed by the processor. The syndication manager component may be operative to receive syndication content from the content producing component, and provide a syndication dialog through the content producing component to syndicate the syndication content using a content delivery platform. The syndication manager component may also syndicate the syndication content to form a syndication resource accessible from the content delivery platform over a network using a syndication referent. Other embodiments are described and claimed. | 06-17-2010 |