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Dennis, NC

Richard Dennis, Garner, NC US

Patent application numberDescriptionPublished
20100120740PRODRUGS OF FUSED HETEROCYCLIC INHIBITORS OF D-AMINO ACID OXIDASE - The invention relates to prodrugs of fused heterocyclic inhibitors of D-amino oxidase (DAAO) and methods of treating diseases and conditions, wherein modulation of D-amino acid oxidase activity, D-serine levels, D-serine oxidative products and NMDA receptor activity in the nervous system of a mammalian subject is effective.05-13-2010
20110034434PRODRUGS OF FUSED HETEROCYCLIC INHIBITORS OF D-AMINO ACID OXIDASE - The invention relates to prodrugs of fused heterocyclic inhibitors of D-amino oxidase (DAAO) and methods of treating diseases and conditions, wherein modulation of D-amino acid oxidase activity, D-serine levels, D-serine oxidative products and NMDA receptor activity in the nervous system of a mammalian subject is effective.02-10-2011

Robert G. Dennis, Raleigh, NC US

Patent application numberDescriptionPublished
20090081752BIOREACTOR, KIT AND METHOD OF USING SAME - A bioreactor, kit, a method of using the device to promoting growing and/or culture of a cell, and a method for regenerating and/or improving the function of mammalian cells. The bioreactor includes a controlling circuit coupled to magnetic field emitter that emits relatively steep and short-lived magnetic field pulses during these an active ephemeral period. The bioreactor also provides a relatively long-term inactive phase in which no magnetic field pulses are imposed. The kit includes the unassembled components of the bioreactor. The method of using the bioreactor and of regenerating and/or improving the function of mammalian cells includes the step of applying a time variant magnetic field through the cell to promote growing and/or culturing, and then introducing the cells to a mammal to regenerate cells.03-26-2009
20090082610OSTEO OR TISSUE HEALING DEVICE, KIT AND METHOD OF USING THE SAME - An osteo or tissue healing device, kit and method of using the device to promote healing of compromised bone or tissue in a living mammal is disclosed. The osteo or tissue healing device includes a magnetic field emitter and a controlling circuit. The magnetic field emitter of the device is electrically coupled to a controlling circuit in which the magnetic field emitter is configured to provide a time variant magnetic field when driven by an electric pulse train from the controlling circuit in such a manner that the time variant magnetic field results in a magnetic (B) field exhibiting a magnetic slew rate of at least about 10 kiloGauss/sec. The controlling circuit of the device is electrically coupled to the magnetic field emitter and is configured to be powered by a power source, in which the controlling circuit is configured to output the electric pulse train driving the magnetic field emitter. It is thought that the steep magnetic field pulses and the relatively long inactive periods play important roles in promoting bone or tissue healing processes. The kit includes the unassembled components of the device. The method of using the osteo or tissue healing device includes the step of applying a time variant magnetic field to bone or tissue to promote healing of the bone or tissue.03-26-2009
20090082613OSTEO OR TISSUE HEALING KIT AND METHOD OF USING THE SAME - An osteo or tissue healing kit and method of promoting the healing of compromised bone or tissue in a living mammal. The osteo or tissue healing device of the kit includes a magnetic field emitter and a controlling circuit, and at least one stem cell. The method of using the osteo or tissue healing kit includes placing at least one stem cell within the compromised bone or tissue and applying a time variant magnetic field.03-26-2009

Robert Glenn Dennis, Chapel Hill, NC US

Patent application numberDescriptionPublished
20090270775DEVICES, SYSTEMS AND METHODS FOR VIBROTACTILE STIMULATION AND NON-INVASIVE NEUROLOGICAL SCREENING - Devices, systems, methods, and computer program products are disclosed for non-invasive diagnosis and screening of neurological disorders. Spatio-temporal mapping can be utilized between the skin and the central nervous system to rapidly, painlessly and quantitatively assess functional connectivity in the central nervous system. Stimulation drivers can be independently operated to control the movement of stimulators to achieve a variety of desired stimulation parameters.10-29-2009
20110130617MAGNETIC SYSTEM FOR TREATMENT OF CELLULAR DYSFUNCTION OF A TISSUE OR AN EXTRACELLULAR MATRIX DISRUPTION OF A TISSUE - A system, kit, and pet bed for treating tissue using magnetic coils connected to a pulse generator. The system can include a power supply, a bi-directional communication and power port, a microcontroller, a processor, a data storage, and a Helmholtz-like magnetic coil pair. The kit can include a saddlebag and a support strap. The pet bed can include bedding, a fabric housing, a Halbach array, and an on/off switch.06-02-2011
20110151491Portable Coagulation Monitoring Device and Method of Assessing Coagulation Response - A device, system and method is disclosed in which small volume blood samples are subjected to shear forces and shear stresses between two parallel planar surfaces to which linear motion trajectories are imparted. The formation of clots or coagulation of the sample is measured from dynamic mechanical coupling which occurs between the two parallel planar surfaces. Detection of the coagulation response can be achieved through optical probing or by measurement of physical effects of the blood sample binding to the planar surfaces, and restricting movement thereof.06-23-2011

Robert W. Dennis, Hickory, NC US

Patent application numberDescriptionPublished
20090067800Fiber optic adapter module and tray - A fiber optic adapter module and tray. The fiber optic adapter module supports fiber optic adapters for fiber optic connections. The fiber optic adapter module may be included on an extendible tray portion of a fiber optic equipment tray and selectively configured to be tilted when extended for providing enhanced access to the fiber optic adapter module. In one embodiment, an adapter module panel of the fiber optic adapter module that supports fiber optic adapters contains at least two forward facing panel surfaces angled to one another to provide more surface area for supporting a higher density of fiber optic adapters and/or for neat routing and organizing of fiber optic connections. One or more fourth flared panel surfaces may also be included on an end(s) of the adapter module panel to provide sufficient interior space for fiber optic connections adjacent or proximate to sides of the fiber optic equipment tray.03-12-2009
20090180737OPTICAL FIBER INTERCONNECTION DEVICES AND SYSTEMS USING SAME - Optical fiber interconnection devices, which can take the form of a module, are disclosed that include an array of optical fibers and multi-fiber optical-fiber connectors, for example, two twelve-port connectors or multiples thereof, and three eight-port connectors or multiples thereof. The array of optical fibers is color-coded and is configured to optically interconnect the ports of the two twelve-port connectors to the three eight-port connectors in a manner that preserves transmit and receive polarization. In one embodiment, the interconnection devices provide optical interconnections between twelve-fiber optical connector configurations to eight-fiber optical connector configurations, such as from twelve-fiber line cards to eight-fiber line cards, without having to make structural changes to cabling infrastructure. In one aspect, the optical fiber interconnection devices provide a migration path from duplex optics to parallel optics.07-16-2009
20100098428Optical interconnection modules for hybrid electrical-optical networks - An optical interconnection module (04-22-2010

Patent applications by Robert W. Dennis, Hickory, NC US