Patent application number | Description | Published |
20080260773 | Saccharide Conjugate Vaccines - The invention provides compositions comprising a combination of two or more monovalent conjugates, each of said two or more monovalent conjugates comprising a carrier protein comprising T cell epitopes from two or more pathogens conjugated to saccharide antigen. The invention also provides a multivalent conjugate comprising two or more antigenically distinct saccharide antigens conjugated to the same carrier protein molecule, wherein the carrier protein comprises T cell epitopes from two or more pathogens. Further compositions comprise one or more of said monovalent conjugates and one or more of said multivalent conjugates. The invention further provides methods for making said compositions and uses for said compositions. | 10-23-2008 |
20090098157 | Helicobacter Pylori Vaccination - A sterile immunogenic preparation of three purified | 04-16-2009 |
20090220544 | ADJUVANTED VACCINES WITH NON-VIRION ANTIGENS PREPARED FROM INFLUENZA VIRUSES GROWN IN CELL CULTURE - An immunogenic composition comprising (i) a non-virion influenza virus antigen prepared from a virus grown in cell culture; and (ii) an adjuvant. Preferred adjuvants comprise oil-in-water emulsions. | 09-03-2009 |
20090220545 | Adjuvant-Sparing Multi-Dose Influenza Vaccination Regimen - An influenza vaccine is administered by a multi-dose regimen, in which (i) a first dose is administered with an adjuvant and (ii) a later dose is administered either without an adjuvant or with a different adjuvant. Thus the invention provides the benefits of a two-dose regimen without also doubling the supply need for a given adjuvant. | 09-03-2009 |
20100158943 | ADMINISTRATION ROUTES FOR PRIMING/BOOSTING WITH INFLUENZA VACCINES - Patients receive a mucosal influenza vaccine and then receive a parenteral influenza vaccine, in that order, typically during different visits to a vaccination center. | 06-24-2010 |
20110150923 | MUCOSAL MENINGOCOCCAL VACCINES - The invention provides immunogenic compositions for mucosal delivery comprising capsular saccharides from at least two of serogroups A, C, W135 and Y of | 06-23-2011 |
20110150931 | RAPID RESPONSES TO DELAYED BOOSTER IMMUNISATIONS - Booster immunization can lead to rapid induction of protective immunity against pathogens (e.g. ≦7 days after the booster dose). This rapid response means that booster immunization can be used at short notice prior to an event that might require an activated immune response. For instance, a subject can be primed at a young age against a pathogen that typically affects more elderly subjects under specific circumstances such that, when the subject is older, the immune response can be mobilized rapidly if those specific circumstances are expected. An example would be to prime a subject against infections that are typically acquired nosocomially and then, soon before a scheduled hospital appointment, to boost their immune response so that they enter hospital in an immune-alert state. | 06-23-2011 |
20110180430 | ADJUVANTED INFLUENZA VACCINES INCLUDING CYTOKINE-INDUCING AGENTS - While oil-in-water emulsions are excellent adjuvants for influenza vaccines, their efficacy can be improved by additionally including other immunostimulating agent(s) to improve cytokine responses, such as γ-interferon response. Thus, a vaccine comprises (i) an influenza virus antigen; (ii) an oil-in-water emulsion adjuvant; and (iii) a cytokine-inducing agent. | 07-28-2011 |
20120039934 | ADJUVANT-SPARING MULTI-DOSE INFLUENZA VACCINATION REGIMEN - An influenza vaccine is administered by a multi-dose regimen, in which (i) a first dose is administered with an adjuvant and (ii) a later dose is administered either without an adjuvant or with a different adjuvant. Thus the invention provides the benefits of a two-dose regimen without also doubling the supply need for a given adjuvant. | 02-16-2012 |
20140248312 | INFLUENZA VACCINES INCLUDING COMBINATIONS OF PARTICULATE ADJUVANTS AND IMMUNOPOTENTIATORS - Influenza vaccines containing insoluble particulate adjuvants have been found to elicit an IgG response that is primarily a TH2 response (IgG1). This response can be shifted towards a TH1 response (IgG2a) by including immunopotentiators in the compositions. Thus the invention provides an immunogenic composition comprising: (i) an influenza virus antigen; (ii) an insoluble particulate adjuvant; and (iii) a immunopotentiator. | 09-04-2014 |
20140370053 | ADJUVANT-SPARING MULTI-DOSE INFLUENZA VACCINATION REGIMEN - An influenza vaccine is administered by a multi-dose regimen, in which (i) a first dose is administered with an adjuvant and (ii) a later dose is administered either without an adjuvant or with a different adjuvant. Thus the invention provides the benefits of a two-dose regimen without also doubling the supply need for a given adjuvant. | 12-18-2014 |
20150246110 | ADJUVANTED INFLUENZA VACCINES INCLUDING CYTOKINE-INDUCING AGENTS - While oil-in-water emulsions are excellent adjuvants for influenza vaccines, their efficacy can be improved by additionally including other immunostimulating agent(s) to improve cytokine responses, such as y-interferon response. Thus, a vaccine comprises (i) an influenza virus antigen; (ii) an oil-in-water emulsion adjuvant; and (iii) a cytokine-inducing agent. | 09-03-2015 |
Patent application number | Description | Published |
20100114605 | MANAGING THE DISTRIBUTION OF DRUG SAMPLES - Computer-based method and system that helps track and manage drug sample distribution, helps ensure drug samples are dispensed and used in a safe and efficient manner, and helps capture information about how drug samples are being distributed and used. The method includes storing inventory information for one or more drug samples received at a prescriber's office, presenting a user-selectable list of drugs available in the inventoried samples and, in response to a user's selection of one of the listed drugs, presenting patient-specific information regarding the selected drug's suitability for dispensing as a sample. The method also includes automatically updating the stored inventory information for the selected drug in response to an indication from the user that a quantity of the selected drug is being dispensed to a patient as a sample. | 05-06-2010 |
20120046967 | Managing the Distribution of Drug Samples - Computer-based method and system that helps track and manage drug sample distribution, helps ensure drug samples are dispensed and used in a safe and efficient manner, and helps capture information about how drug samples are being distributed and used. The method includes storing inventory information for one or more drug samples received at a prescriber's office, presenting a user-selectable list of drugs available in the inventoried samples and, in response to a user's selection of one of the listed drugs, presenting patient-specific information regarding the selected drug's suitability for dispensing as a sample. The method also includes automatically updating the stored inventory information for the selected drug in response to an indication from the user that a quantity of the selected drug is being dispensed to a patient as a sample. | 02-23-2012 |
20130204632 | Managing the Distribution of Drug Samples - Computer-based method and system that helps track and manage drug sample distribution, helps ensure drug samples are dispensed and used in a safe and efficient manner, and helps capture information about how drug samples are being distributed and used. The method includes storing inventory information for one or more drug samples received at a prescriber's office, presenting a user-selectable list of drugs available in the inventoried samples and, in response to a user's selection of one of the listed drugs, presenting patient-specific information regarding the selected drug's suitability for dispensing as a sample. The method also includes automatically updating the stored inventory information for the selected drug in response to an indication from the user that a quantity of the selected drug is being dispensed to a patient as a sample. | 08-08-2013 |
20150154377 | Managing the Distribution of Drug Samples - Computer-based method and system that helps track and manage drug sample distribution, helps ensure drug samples are dispensed and used in a safe and efficient manner, and helps capture information about how drug samples are being distributed and used. The method includes storing inventory information for one or more drug samples received at a prescriber's office, presenting a user-selectable list of drugs available in the inventoried samples and, in response to a user's selection of one of the listed drugs, presenting patient-specific information regarding the selected drug's suitability for dispensing as a sample. The method also includes automatically updating the stored inventory information for the selected drug in response to an indication from the user that a quantity of the selected drug is being dispensed to a patient as a sample. | 06-04-2015 |