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Degrave

Jeremy Degrave, Les Fontenelles FR

Patent application numberDescriptionPublished
20120083769Double Offset Surgical Tool Handle Assembly To Provide Greater Offset From The Coronal Plane - A surgical tool handle for releasable connection to a surgical tool is described. The tool handle comprises a housing providing a linkage chamber extending from a proximal housing grip end to a distal housing tool end for receiving a tool. A tool linkage is partially housed within the linkage chamber. That way, manipulation of the tool linkage causes a locking pawl to pivot with respect to the housing from an open configuration ready to receive a tool for attachment to the housing to a closed configuration engageable with the tool supported at the distal housing tool end.04-05-2012

Lies Degrave, Aarsele BE

Patent application numberDescriptionPublished
20090306189Methods for Controlling Pests Using Rnai - The present invention relates to methods for controlling pest infestation using double stranded RNA molecules. The invention provides methods for producing transgenic cells expressing the double stranded RNA molecules, as well as compositions and commodity products containing or treated with such molecules.12-10-2009

Wim Degrave, Paris FR

Patent application numberDescriptionPublished
20090298110Identification and characterization of racemases, definition of protein signatures, and a test for detecting D-amino acid and for screening molecules capable of inhibiting the activity of racemase, especially proline racemase - This invention relates to the identification and characterization of racemases and definition of protein signatures of these racemases. More particularly, this invention relates to the identification of nucleic acid molecules encoding a peptide consisting of a motif characteristic of the protein signatures, and to the peptides consisting of these motifs and more specifically SEQ ID NOS:1-4. This invention also relates to antibodies specific for the peptides and to immune complexes of these antibodies with the peptides. Further, the invention relates to methods and kits for detecting racemases using the nucleic acid molecules of the invention, as well as the peptides consisting of the motifs and antibodies to these peptides.12-03-2009

Wim Degrave, Paris Cedex 15 FR

Patent application numberDescriptionPublished
20100196943IDENTIFICATION AND CHARACTERIZATION OF RACEMASES, DEFINITION OF PROTEIN SIGNATURES, AND A TEST FOR DETECTING D-AMINO ACID AND FOR SCREENING MOLECULES CAPABLE OF INHIBITING THE ACTIVITY OF RACEMASE, ESPECIALLY PROLINE RACEMASE - This invention relates to the identification and characterization of racemases and definition of protein signatures of these racemases. More particularly, this invention relates to the identification of nucleic acid molecules encoding a peptide consisting of a motif characteristic of the protein signatures, and to the peptides consisting of these motifs and more specifically SEQ ID NOS:1-4. This invention also relates to antibodies specific for the peptides and to immune complexes of these antibodies with the peptides. Further, the invention relates to methods and kits for detecting racemases using the nucleic acid molecules of the invention, as well as the peptides consisting of the motifs and antibodies to these peptides. 08-05-2010

Wim Degrave, Paris Cedex FR

Patent application numberDescriptionPublished
20120058135Identification and characterization of racemases, definition of protein signatures, and a test for detecting D-amino acid and for screening molecules capable of inhibiting the activity of racemase, especially proline racemase - This invention relates to the identification and characterization of racemases and definition of protein signatures of these racemases. More particularly, this invention relates to the identification of nucleic acid molecules encoding a peptide consisting of a motif characteristic of the protein signatures, and to the peptides consisting of these motifs and more specifically SEQ ID NOS: 1-4. This invention also relates to antibodies specific for the peptides and to immune complexes of these antibodies with the peptides. Further, the invention relates to methods and kits for detecting racemases using the nucleic acid molecules of the invention, as well as the peptides consisting of the motifs and antibodies to these peptides.03-08-2012

Wim M. Degrave, Rio De Janeiro BR

Patent application numberDescriptionPublished
20090162844Identification and characterization of racemases, definition of protein signatures, and a test for detecting D-amino acid and for screening molecules capable of inhibiting the activity of racemase, especially proline racemase - This invention provides identification and characterization of racemases and definition of protein signatures of these racemases. This invention also provides identification of nucleic acid molecules encoding a peptide consisting of a motif characteristic of the protein signatures, and to the peptides consisting of these motifs. Antibodies specific for the peptides and to immune complexes of these antibodies with the peptides are also provided. Further, the invention relates to methods and kits for detecting racemases using the nucleic acid molecules of the invention, as well as the peptides consisting of the motifs and antibodies to these peptides.06-25-2009
20120076815IDENTIFICATION AND CHARACTERIZATION OF RACEMASES, DEFINITION OF PROTEIN SIGNATURES, AND A TEST FOR DETECTING D-AMINO ACID AND FOR SCREENING MOLECULES CAPABLE OF INHIBITING THE ACTIVITY OF RACEMASE, ESPECIALLY PROLINE RACEMASE - This invention provides identification and characterization of racemases and definition of protein signatures of these racemases. This invention also provides identification of nucleic acid molecules encoding a peptide consisting of a motif characteristic of the protein signatures, and to the peptides consisting of these motifs. Antibodies specific for the peptides and to immune complexes of these antibodies with the peptides are also provided. Further, the invention relates to methods and kits for detecting racemases using the nucleic acid molecules of the invention, as well as the peptides consisting of the motifs and antibodies to these peptides.03-29-2012

Patent applications by Wim M. Degrave, Rio De Janeiro BR

Wim Maurits Sylvain Degrave, Rio De Janeiro BR

Patent application numberDescriptionPublished
20100017356Method for Identifying Protein Patterns in Mass Spectrometry - The present invention refers to a medical diagnostic method based on proteomic and/or genomic patterns, using data obtained by mass spectrometry. The method also allows classifying the patients as to their disease stage Additionally, present invention also refers to two new biomarkers for the Hodgkin Disease medical diagnosis. Based on the SVM analysis, one localizes the windows of interest and later on uses the mass spectrum so to allow the biomarkers localization, so that the identification of said biomarkers occur by means of a 2D gel ou by mass spectrometry.01-21-2010