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Debart
Francoise Debart, Combaillaux FR
| Patent application number | Description | Published |
|---|---|---|
| 20100069623 | Method for preparing oligonucleotides - A solution phase synthesis method for preparing an oligonucleotide, wherein at least some of the reagents are solid supported. The method suitable for large-scale synthesis comprises coupling a protected compound with a nucleotide derivative having a protection group in the presence of a solid supported activator to give an elongated oligonucleotide with a P(III)-internucleotide bond; optionally processing the elongated oligonucleotide by capping by reaction with a solid supported capping agent and/or by oxidizing or sulfurizing by reaction of the oligonucleotide with a solid supported oxidizing or sulfurization reagent; and removing the protection group. The coupling may include reacting a 3′-protected compound of formula: | 03-18-2010 |
| 20110224424 | Method for preparing oligonucleotides - A solution phase synthesis method for preparing an oligonucleotide, wherein at least some of the reagents are solid supported. The method suitable for large- scale synthesis comprises coupling a protected compound with a nucleotide derivative having a protection group in the presence of a solid supported activator to give an elongated oligonucleotide with a P(III)-internucleotide bond; optionally processing the elongated oligonucleotide by capping by reaction with a solid supported capping agent and/or by oxidizing or sulfurizing by reaction of the oligonucleotide with a solid supported oxidizing or sulfurization reagent; and removing the protection group. The coupling may include reacting a 3′-protected compound of formula: | 09-15-2011 |
Françoise Debart, Combaillaux FR
| Patent application number | Description | Published |
|---|---|---|
| 20110275793 | Chemical RNA Synthesis Method - The invention relates to a method for the chemical synthesis of RNA, comprising the following steps: a) bonding to a solid support of a monomer having formula (II) in which—X | 11-10-2011 |
Pere Ristol Debart, Sabadell ES
| Patent application number | Description | Published |
|---|---|---|
| 20090176709 | PROCESS FOR OBTAINING A CONCENTRATE OF VON WILLEBRAND FACTOR OR A COMPLEX OF FACTOR VIII/VON WILLEBRAND FACTOR AND USE OF THE SAME - The process is characterised by the preparation of a solution of Von Willebrand Factor or a complex of Factor VIII/Von Willebrand Factor which contains VWF and a concentration of up to 12 IU VWF:RCo/ml and a Von Willebrand Factor/Factor VIII ratio of 0.4 or more; and then proceeding with nanofiltration of the solution prepared in a) through a filter having a pore size of less than 35 nanometres. | 07-09-2009 |
| 20110137283 | PROCESS FOR OBTAINING HIGH EFFICIENCY HUMAN ALBUMIN FOR USE IN DETOXIFICATION THERAPY - A process for purifying and collecting albumin from plasma and plasma fractions involves diafiltration of an albumin-containing plasma fraction; stabilizing the resulting albumin fraction with sodium chloride and an amino acid in the absence of any added fatty acid; pasteurizing the stabilized albumin fraction; and diafiltering the pasteurized fraction to remove, along other things, stabilizers. In one embodiment, the amino acid stabilizing agent is acetyl tryptophan. The resulting albumin has at least about 80% albumin binding capacity relative to natural plasma albumin, and is storage stable for about 30 months at 30° C. | 06-09-2011 |
Stephane Debart, Houilles FR
| Patent application number | Description | Published |
|---|---|---|
| 20100169759 | SYSTEMS AND METHODS TO CREATE A MULTIDIMENSIONAL EXPRESSION CALCULATED MEMBER IN A SPREADSHEET CELL - According to some embodiments, a system, method, means, and/or computer program code are provided to facilitate use of a spreadsheet application to access information stored in a multidimensional data source. Some embodiments include receiving, at an analyzer module, a change indication from the spreadsheet application. The change indication may be, for example, associated with a spreadsheet formula of the spreadsheet application entered by a user into a spreadsheet cell. In response to the change indication, the spreadsheet formula may be translated into a multidimensional expression calculation associated with the multidimensional data source. The spreadsheet formula in the spreadsheet cell may then be automatically replaced with information associated with the multidimensional expression calculation. | 07-01-2010 |