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De Leon

Adalberto Perez De Leon, Wake Forest, NC US

Patent application numberDescriptionPublished
201002491941-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF - Provided are 1-aryl-5-alkyl pyrazole compounds, of formula (I):09-30-2010

Belinda De Leon, San Francisco, CA US

Patent application numberDescriptionPublished
20110319317TREATMENT OF SIRTUIN 1 (SIRT1) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SIRT1 - The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Sirtuin 1 (SIRT1), in particular, by targeting natural antisense polynucleotides of Sirtuin 1 (SIRT1). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of SIRT 1.12-29-2011

Belinda De Leon, West Palm Beach, FL US

Patent application numberDescriptionPublished
20110237649TREATMENT OF SIRTUIN 1 (SIRT1) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SIRTUIN 1 - Oligonucleotide compounds modulate expression and/or function of Sirtuin 1 (SIRT1) polynucleotides and encoded products thereof. Methods for treating diseases associated with Sirtuin 1 (SIRT1) comprise administering one or more Oligonucleotide compounds designed to inhibit the SIRT1 natural antisense transcript to patients.09-29-2011

Briccio De Leon, San Pablo City PH

Patent application numberDescriptionPublished
20110062148INDUCTION SOLDERING OF PHOTOVOLTAIC SYSTEM COMPONENTS - A method comprises positioning a pair of photovoltaic wafers in a side-by-side arrangement. An interconnect is placed on the pair of wafers such that the interconnect overlaps both wafers of the pair, solder material being provided between the interconnect and the respective wafers. A solder head is then located adjacent the interconnect, and the coil is energized to effect inductive heating of the solder material. The solder head comprises an induction coil shaped to define an eye, and a magnetic field concentrator located at least partially in the eye of the coil. The magnetic field concentrator defines a passage extending axially through the eye of the coil, and may be of a material with a high magnetic permeability.03-17-2011

Conrado De Leon, Manila PH

Patent application numberDescriptionPublished
20100245025SOLDERLESS SURFACE MOUNT FUSE - A surface mount fuse in one embodiment includes an insulative body, first and second conductive and caps attached to the insulative body, each end cap defining an aperture, and a fuse element extending (i) through the insulative body and the apertures and (ii) along outside surfaces of the first and second conductive end caps in such a way that solder used to attach the first and second conductive end caps to an external medium also fastens the fuse element to the first and second end caps.09-30-2010

Daen De Leon, Kobenhavn DK

Patent application numberDescriptionPublished
20090264300ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES - Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).10-22-2009

Diva D. De Leon, Philadelphia, PA US

Patent application numberDescriptionPublished
20080269130Methods and compositions for treating hypoglycemic disorders - This invention relates to methods of treating and ameliorating congenital and neonatal hyperinsulinism and post-prandial hypoglycemia, comprising the step of administering an antagonist of the Glucagon-Like Peptide-1 (GLP-1) receptor, e.g. a GLP-1 fragment or analogue thereof.10-30-2008

Hector De Leon, San Carlos, CA US

Patent application numberDescriptionPublished
20090150134Simulating Patient-Specific Outcomes - The invention encompasses systems, methods, and apparatus for predicting clinical outcomes and monitoring an individual's response to a therapeutic regimen. The invention further encompasses methods for predicting cardiovascular risk based a genetic marker status and methods for modifying a computer to reflect genetic data and for incorporating genetic markers into a virtual population.06-11-2009

Hector Ramirez De Leon, O'Fallon, MO US

Patent application numberDescriptionPublished
20110271385PLANTS AND SEEDS OF HYBRID CORN VARIETY CH867615 - According to the invention, there is provided seed and plants of the hybrid corn variety designated CH867615. The invention thus relates to the plants, seeds and tissue cultures of the variety CH867615, and to methods for producing a corn plant produced by crossing a corn plant of variety CH867615 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH867615.11-03-2011
20110277094PLANTS AND SEEDS OF HYBRID CORN VARIETY CH711877 - According to the invention, there is provided seed and plants of the hybrid corn variety designated CH711877. The invention thus relates to the plants, seeds and tissue cultures of the variety CH711877, and to methods for producing a corn plant produced by crossing a corn plant of variety CH711877 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH711877.11-10-2011
20110277096PLANTS AND SEEDS OF HYBRID CORN VARIETY CH287946 - According to the invention, there is provided seed and plants of the hybrid corn variety designated CH287946. The invention thus relates to the plants, seeds and tissue cultures of the variety CH287946, and to methods for producing a corn plant produced by crossing a corn plant of variety CH287946 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH287946.11-10-2011
20110277129PLANTS AND SEEDS OF HYBRID CORN VARIETY CH851446 - According to the invention, there is provided seed and plants of the hybrid corn variety designated CH851446. The invention thus relates to the plants, seeds and tissue cultures of the variety CH851446, and to methods for producing a corn plant produced by crossing a corn plant of variety CH851446 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH851446.11-10-2011
20110277174PLANTS AND SEEDS OF HYBRID CORN VARIETY CH116894 - According to the invention, there is provided seed and plants of the hybrid corn variety designated CH116894. The invention thus relates to the plants, seeds and tissue cultures of the variety CH116894, and to methods for producing a corn plant produced by crossing a corn plant of variety CH116894 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH116894.11-10-2011
20110277175PLANTS AND SEEDS OF HYBRID CORN VARIETY CH889077 - According to the invention, there is provided seed and plants of the hybrid corn variety designated CH889077. The invention thus relates to the plants, seeds and tissue cultures of the variety CH889077, and to methods for producing a corn plant produced by crossing a corn plant of variety CH889077 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH889077.11-10-2011
20110283394PLANTS AND SEEDS OF HYBRID CORN VARIETY CH918848 - According to the invention, there is provided seed and plants of the hybrid corn variety designated CH918848. The invention thus relates to the plants, seeds and tissue cultures of the variety CH918848, and to methods for producing a corn plant produced by crossing a corn plant of variety CH918848 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH918848.11-17-2011

Joseph Emil De Leon, Chino, CA US

Patent application numberDescriptionPublished
20090094767Apparatus for cleaning and maintenance of golf equipment - An apparatus for maintaining shoe cleats and cleaning the face of golf club heads that has an elongated brush mounted on a stem emanating from a first side of a brush unit and a plurality of bristles emanating from a second side of the brush unit. When not in use, the elongated brush stores in a storage cavity that is part of a separate cleat removal fixture. The cleat removal fixture and brush unit a held together by a friction fitting.04-16-2009

Manolo De Leon, Mississauga CA

Patent application numberDescriptionPublished
20110126490LEAF COMPACTOR - Apparatus for use with yard waste bags of the flat-bottom paper type is disclosed. The apparatus comprises a base and a shaft, the shaft terminating at one end in a handle and at the other end in the base. The shaft is hollow. The base and the shaft are constructed out of plastic and in the form of a hand tamper. The tamper is sized such that, when the tamper is operatively disposed within an empty one of said bags with the base on the bag bottom, the base substantially fully occupies and overlies the bag bottom and the handle projects above the bag.06-02-2011

Mark Henry Perez De Leon, Bataan PH

Patent application numberDescriptionPublished
20100007079Media Handling Device Having Media Shingling Mechanism For Providing Uniform Inter-Page Gap Between Successive Media Sheets - A media handling device includes a media shingling mechanism having a roller actuator located adjacent an upper portion of a media stack and downstream thereof relative to a predetermined direction of an uppermost sheet from the stack toward a media restraint dam located upstream thereof. The roller actuator undergoes counterclockwise rotation in response to upward moving contact by successive sheets in the upper portion of the stack against a peripheral segment of the roller actuator as the stack is moved vertically upward in a rectilinear direction toward the roller actuator. The counterclockwise rotation of the roller actuator and upward movement of the upper portion of the stack produces a lateral displacement of successive sheets toward the dam so as to produce shingling of successive sheets of the upper portion of the stack relative to one another, providing a uniform inter-page gap between successive sheets.01-14-2010

Mony De Leon, New York, NY US

Patent application numberDescriptionPublished
20100228115CSF biomarker dilution factor corrections by MIRI imaging and algorithm - A method is disclosed for providing a correcting factor for the dilution of measurements of at least one biomarker in cerebrospinal fluid (CSF). The method comprises providing semi-automated measurements of the ventricular system by MRI scans quantitative anatomical protocols, determining a measurement of biomarker levels in CSF that has been extracted, correcting the measurement of the level of said at least one biomarker'according to the ventricular size, and providing a corrected result of the measurement determined in step (b), said corrected result accounting for concentration dilution due to the change in ventricular size. The method is particularly suited for the measurement of all biomarkers found in the CSF, such as those associated with mild cognitive impairment (MCI) and Alzheimer's Disease.09-09-2010

Pablo De Leon, Philadelphia, PA US

Patent application numberDescriptionPublished
20120115885Quinolinone PDE2 Inhibitors - The present invention is directed to quinolinone compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.05-10-2012