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De Kruif, NL
Cornelis A. De Kruif, El De Bilt NL
| Patent application number | Description | Published |
|---|---|---|
| 20100297153 | Binding molecules for treatment and detection of cancer - Provided are new tumor-associated antigens, binding molecules that specifically bind to the antigens, nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules, and methods of identifying or producing the binding molecules. The tumor-associated antigens are expressed on cancer cells and binding molecules capable of specifically binding to the antigens can be used in the diagnosis, prevention and/or treatment of cancer. | 11-25-2010 |
Cornelis A. De Kruif, De Bilt NL
| Patent application number | Description | Published |
|---|---|---|
| 20100146647 | Antibody producing non-human mammals - Described are transgenic, non-human animals comprising a nucleic acid encoding an immunoglobulin light chain, whereby the immunoglobulin light chain is human, human-like, or humanized. The nucleic acid is provided with a means that renders it resistant to DNA rearrangements and/or somatic hypermutations. In one embodiment, the nucleic acid comprises an expression cassette for the expression of a desired molecule in cells during a certain stage of development in cells developing into mature B cells. Further provided is methods for producing an immunoglobulin from the transgenic, non-human animal. | 06-10-2010 |
| 20100172917 | Binding molecules against SARS-coronavirus and uses thereof - Described are binding molecules that specifically bind to SARS-CoV, nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules, and methods of identifying or producing the binding molecules. The binding molecules are capable of specifically binding to SARS-CoV, and can be used in the diagnosis, prophylaxis, and/or treatment of a condition resulting from SAR. | 07-08-2010 |
Cornelis Adriaan De Kruif, El De Bilt NL
| Patent application number | Description | Published |
|---|---|---|
| 20090054254 | Method for Preparing Immunoglobulin Libraries - The invention relates to the generation of immunoglobulin libraries and the identification and production of immunoglobulins having a specific functionality of interest. | 02-26-2009 |
Cornelis Gijsbertus De Kruif, Kk Woudenberg NL
| Patent application number | Description | Published |
|---|---|---|
| 20100068340 | ICE-STRUCTURING PEPTIDES OF LACTIC ORIGIN - The present invention relates to the use of peptides of lactic origin as ice-structuring agents, to their use in the manufacture of frozen products, and to the frozen products comprising them. | 03-18-2010 |
Petrus W.g.m. De Kruif, Goirle NL
| Patent application number | Description | Published |
|---|---|---|
| 20100246950 | Color Enhancement - In an image processor, a color format converter (CFC) converts a pixel (P | 09-30-2010 |
Robertus Cornelis Martinus De Kruif, Eindhoven NL
| Patent application number | Description | Published |
|---|---|---|
| 20100329290 | LITHOGRAPHIC APPARATUS, EXCIMER LASER AND DEVICE MANUFACTURING METHOD - A CD-pitch dependency for a lithographic pattern printing process is related to the spectral intensity distribution of radiation used for projecting the pattern. A CD-pitch dependency can vary from one system to another. This can result in an iso-dense bias mismatch between systems. The invention addresses this problem by providing a lithographic apparatus including an illumination system for providing a projection beam of radiation, a projection system for projecting a patterned beam onto a target portion of a substrate, and a substrate table for holding the substrate, with a controller to provide an adjustment of the spectral distribution of radiant intensity of the projection beam. The adjustment of the spectral intensity distribution is based on data relating to an iso dense bias, and comprises a broadening of the spectral bandwidth or a change of shape of the spectral intensity distribution. | 12-30-2010 |
| 20110043775 | LITHOGRAPHIC APPARATUS, DISTORTION DETERMINING METHOD, AND PATTERNING DEVICE - The invention relates to a lithographic apparatus arranged to transfer a pattern from a patterning device onto a substrate, wherein said apparatus is operable to measure higher-order distortions and/or image plane deviations of the patterning device, said apparatus comprising: a device for transmission image detection; and a processor configured and arranged to model higher-order distortions of the patterning device using signals received from the device for transmission image detection; wherein said patterning device has a main imaging field, and a perimeter and said apparatus is operable to model said higher-order distortions using signals resultant from alignment structures comprised in said perimeter and/or in the imaging field. | 02-24-2011 |