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De Brabander
Gregory De Brabander, San Jose, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110181664 | Forming Self-Aligned Nozzles - A method of forming a nozzle plate of a fluid ejection device includes performing a first etch from a first side of a wafer to form a tapered region, forming an oxide layer in the tapered region such that a depth of the oxide layer on the tapered walls is greater than a depth of the oxide layer on the floor, performing a second etch from the first side to remove the oxide layer from the floor and a portion of the oxide layer from the tapered wall, and performing a third etch from the first side to form an outlet passage having a straight wall. | 07-28-2011 |
Jef D. De Brabander, Dallas, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090312379 | Dimeric Small Molecule Potentiators of Apoptosis - Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-L-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent linker. Target cancerous or inflammatory cells are contacted with an effective amount of an active, dimeric Smac mimetic, and a resultant increase in apoptosis of the target cells is detected. The contacting step may be effected by administering to a pharmaceutical composition comprising a therapeutically effective amount of The compoundic mimetic, wherein the individual may be subject to concurrent or antecedent radiation or chemotherapy for treatment of a neoproliferative pathology. | 12-17-2009 |
Jef K. De Brabander, Flower Mound, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20110003836 | Pro-Neurogenic Compounds - This invention relates generally to stimulating neurogenesis (e.g., post-natal neurogenesis, e.g., post-natal hippocampal neurogenesis) and protection from neuron cell death. | 01-06-2011 |
| 20110015217 | Pro-Neurogenic Compounds - This invention relates generally to stimulating neurogenesis (e.g., post-natal neurogenesis, e.g., post-natal hippocampal neurogenesis) and protecting from neuron cell death. | 01-20-2011 |
Jef K. De Brabander, Dallas, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090281155 | Dimeric Small Molecule Potentiators of Apoptosis - Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-L-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent linker. Target cancerous or inflammatory cells are contacted with an effective amount of an active, dimeric Smac mimetic, and a resultant increase in apoptosis of the target cells is detected. The contacting step may be effected by administering to a pharmaceutical composition comprising a therapeutically effective amount of The compoundic mimetic, wherein the individual may be subject to concurrent or antecedent radiation or chemotherapy for treatment of a neoproliferative pathology. | 11-12-2009 |
| 20110124585 | Dimeric Small Molecule Potentiators of Apoptosis - Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-L-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent linker. Target cancerous or inflammatory cells are contacted with an effective amount of an active, dimeric Smac mimetic, and a resultant increase in apoptosis of the target cells is detected. The contacting step may be effected by administering to a pharmaceutical composition comprising a therapeutically effective amount of The compoundic mimetic, wherein the individual may be subject to concurrent or antecedent radiation or chemotherapy for treatment of a neoproliferative pathology. | 05-26-2011 |
Jef K. De Brabander, Lewisville, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20080249162 | PALMEROLIDES: METHODS OF PREPARATION AND DERIVATIVES THEREOF - Organic compounds having Formulas I and II are provided where the variables have the values described herein. | 10-09-2008 |