De Angelis
Angela De Angelis, Bloomfield Hills, MI US
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20090044920 | Magnetic drapery valance ties - A magnetic apparatus for holding selected drapery sections in a predetermined configuration includes a first base member of predetermined shape housing a permanent magnet, and an elongated flexible connector attached proximal one end to the first base member. A second base member housing a ferromagnetic member is disposed adjacent an opposite end of the elongated flexible connector. | 02-19-2009 |
Annalisa De Angelis, Tivoli FR
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20130271765 | LASER EMISSION DEVICE AND METHOD FOR THE SPECTROSCOPIC ANALYSIS OF A SAMPLE - According to one aspect, the invention relates to a laser emission device for the spectroscopic analysis of a sample, comprising: a primary laser source ( | 10-17-2013 |
Antonio De Angelis, Farnborough GB
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20160112079 | ADJACENT-CHANNEL INTERFERENCE AND SPUR HANDLING IN WIRELESS COMMUNICATIONS - Aspects of the present disclosure provides a wireless communication apparatus configured to handle adjacent-channel interference (ACI) and spur. The apparatus receives a signal utilizing a communication interface. The apparatus is configured to perform a single discrete Fourier transform (DFT) on the signal to generate frequency domain data. The apparatus is further configured to determine respective energy of a plurality of adjacent channels of the signal utilizing the frequency domain data. The apparatus is further configured to determine one or more potential interfering channels among the adjacent channels, wherein each of the potential interfering channels has an energy greater than a qualifying threshold. The apparatus is further configured to identify one or more dominant interfering channels from among the potential interfering channels. The apparatus is further configured to detect ACI based on the one or more dominant interfering channels. | 04-21-2016 |
Christopher De Angelis, Southborough, MA US
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20150256474 | RESOURCE MANAGEMENT FOR MULTIPLE DESKTOP CONFIGURATIONS FOR SUPPORTING VIRTUAL DESKTOPS OF DIFFERENT USER CLASSES - A service provider can efficiently allocate server computer resources to tenant users, while isolating tenants from such allocation decisions. A tenant specifies a desktop model to be used for virtual desktops to be provisioned for a pool of users. The service provider has desktop managers for each tenant, each of which manages a homogeneous set of server computers to be used for provisioning virtual desktops for the tenant. Different desktop managers for a tenant are used to manage different sets of server computers to support virtual desktops using different desktop models or desktop models with different resource requirements. A resource manager of the service provider assigns virtual desktops to a desktop manager in a manner that optimizes the utilization of the server computers by using information about the desktop model used by the virtual desktops. | 09-10-2015 |
Claudio De Angelis, Munster DE
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20110247902 | SUPPORT ELEMENT SYSTEM FOR ELEVATORS - A support element system, particularly for elevators, has at least one support element having two load-bearing tensile carriers which are arranged horizontally adjacent to one another and which are enclosed in a common elastomeric casing separating the two tensile carriers. The tensile carriers respectively have an opposite direction of wrap. The system has a drive pulley for transmission of a drive force to the at least one support element, wherein the drive pulley has a contoured traction surface with two support surfaces, which are provided for transmission of the drive force and which co-operate with the support element. | 10-13-2011 |
Elena De Angelis, Cambridgeshire GB
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20100021473 | Bispecific Ligands With Binding Specificity to Cell Surface Targets and Methods of Use Therefor - Disclosed are ligands comprising a first polypeptide domain having a binding site with binding specificity for a first cell surface target and a second polypeptide domain having a binding site for a second cell surface target, wherein each target are different and on the same cell. In some embodiments, the ligands described further comprise a toxin. In other embodiments, the ligands further comprise half-life extending moieties. Also disclosed are methods of using these ligands. In particular, the use of these ligands for cancer therapy is described. | 01-28-2010 |
20110300158 | ANTI-SERUM ALBUMIN BINDING VARIANTS - The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-14, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts. | 12-08-2011 |
20110305696 | ANTI-SERUM ALBUMIN BINDING VARIANTS - The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-11, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts. | 12-15-2011 |
20120114647 | ANTI-SERUM ALBUM SINGLE VARIABLE DOMAINS - The invention relates to improved anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variable domains, compositions, nucleic acids, vectors and hosts. | 05-10-2012 |
Elena De Angelis, Stevenage GB
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20160075774 | ANTI-SERUM ALBUMIN BINDING VARIANTS - The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-14, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts. | 03-17-2016 |
Elena De Angelis, Brentford GB
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20150284454 | ANTI-SERUM ALBUMIN BINDING VARIANTS - The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-11, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts. | 10-08-2015 |
Elena De Angelis US
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20110223168 | LIGAND THAT HAS BINDING SPECIFICITY FOR IL-4 AND/OR IL-13 - The invention provides a dual-specific ligand comprising a first immunoglobulin variable domain having a first binding specificity and a complementary or non-complementary immunoglobulin variable domain having a second binding specificity. | 09-15-2011 |
Elena De Angelis, Cambridge GB
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20100081792 | Ligand - The invention provides a dual-specific ligand comprising a first and second single variable domain, each having binding specificity for a antigenic target. The invention also provides for a single variable domain monomer ligand that specifically binds to an antigenic target. | 04-01-2010 |
20120253017 | STEM CELL TARGETING - The present invention describes an antigen-binding construct comprising a first agent which binds to a stem cell specific marker molecule and a second agent which binds to a tissue specific marker molecule. In particular, the invention describes a construct wherein the tissue specific marker is a muscle specific marker molecule. Such a construct may be used in a pharmaceutical composition for use in muscle regeneration or heart disease. | 10-04-2012 |
20130129746 | ANTI-SERUM ALBUMIN BINDING VARIANTS - The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-11, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts. | 05-23-2013 |
20130202597 | ANTI-SERUM ALBUMIN BINDING VARIANTS - The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts. | 08-08-2013 |
20130230519 | ANTI-SERUM ALBUMIN BINDING VARIANTS - The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-14-10, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts. | 09-05-2013 |
20140140996 | ANTI-SERUM ALBUMIN BIDING VARIABLE DOMAINS - The invention relates to improved anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variable domains, compositions, nucleic acids, vectors and hosts. | 05-22-2014 |
20160052998 | ANTI-SERUM ALBUMIN BINDING VARIANTS - The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts. | 02-25-2016 |
Flavio De Angelis, San Diego, CA US
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20100284303 | METHOD AND APPARATUS FOR GENERATING AND EXCHANGING INFORMATION FOR COVERAGE OPTIMIZATION IN WIRELESS NETWORKS - The subject specification is directed towards generating and exchanging information for coverage optimization in wireless networks. Aspects are disclosed for facilitating a distributed coverage optimization. A communication is established with at least one external entity, and a coverage-related measurement is received from the at least one external entity. A coverage parameter is then self-optimized as a function of the coverage-related measurement. | 11-11-2010 |
20140369336 | APPARATUS AND METHOD FOR DISTRIBUTED UPDATING OF A SELF ORGANIZING NETWORK - The present disclosure presents a method and an apparatus for distributed updating of a self organizing network. For example, the disclosure presents a method for transmitting, via a transmitting component at a base station, a portion of data collected at the base station to a network entity, wherein the data collected at the base station is received by the base station from one or more user equipments (UE) in communication with one or more base stations, wherein the base station is one of the one or more base stations, receiving feedback, from the network entity, associated with one or more network parameters of the base station, wherein the feedback received from the network entity is determined at the network entity at least based on the portion of data transmitted from the one or more base stations to the network entity, and updating the one or more network parameters at the base station based on the feedback received from the network entity and local information at the base station. As such, distributed updating of a self organizing network may be achieved. | 12-18-2014 |
Garey De Angelis, Charleston, SC US
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20090050499 | PROTECTIVE ASSEMBLY FOR PORTABLE DIGITAL DEVICE - A protective case for a portable digital media device includes a hinged element and an aperture registered with an input element for such device, to provide protection against inadvertent damage to the device, to selectively operate as a stand to maintain the device in an upright position, and enable user access to the input element when the case is closed. | 02-26-2009 |
Gilbert De Angelis, New York, NY US
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20110204039 | APPARATUS FOR USE IN DIRECT RESISTANCE HEATING OF PLATINUM-CONTAINING VESSELS - An apparatus for use in direct resistance heating of a molten glass-carrying vessel, such as a finer or connecting pipe, is provided. The apparatus comprises a flange comprises a plurality of electrically-conductive rings that include an inner ring joined to the vessel's exterior wall during use of the flange and an outer ring that receives electric current during use of the flange. The innermost ring comprises a high-temperature resistant metal preferably comprising at least 80% platinum, and the outermost ring preferably comprising at least 99.0% nickel. This combination of materials both increases the reliability of the flange and reduces its cost. Either one or both of the width or thickness of one or both of the inner or outer rings varies as a function of angular position relative to the vessel. The width and/or thickness of the inner and the outer rings with relation to each other produces a uniform current distribution in the flange and the vessel. | 08-25-2011 |
Gilbert De Angelis, Lindley, NY US
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20110113827 | Methods and Apparatus for Thermally Conditioning Molten Glass - An oblong conduit ( | 05-19-2011 |
20110126592 | Devices for Controlling Atmosphere over Molten-Glass Free-Surfaces - A chamber ( | 06-02-2011 |
20110203321 | APPARATUS FOR SEALING A JOINT BETWEEN VESSELS FOR CONVEYING MOLTEN GLASS - A sealing apparatus for use in conveying molten glass from a first vessel to a second vessel, wherein at least a portion of the first vessel is nested within the second vessel without contact between the first and second vessels, and a flexible member comprising a gas-tight seal separates an atmosphere enclosed by the sealing apparatus and an ambient atmosphere. The sealing apparatus is useful for flexibly sealing a non-contact joint between conduits for supplying molten glass to a forming body. | 08-25-2011 |
20120266633 | APPARATUS FOR SEALING A JOINT BETWEEN VESSELS FOR CONVEYING MOLTEN GLASS - A sealing apparatus for use in conveying molten glass from a first vessel to a second vessel, wherein at least a portion of the first vessel is nested within the second vessel without contact between the first and second vessels, and a flexible member comprising a gas-tight seal separates an atmosphere enclosed by the sealing apparatus and an ambient atmosphere. The sealing apparatus is useful for flexibly sealing a non-contact joint between conduits for supplying molten glass to a forming body. | 10-25-2012 |
20120275483 | ELECTRODE HOLDER FOR ELECTRIC GLASS MELTING - An electrode holder for use in a furnace for melting a batch material to form molten glass is disclosed comprising a refractory coated nose member presented to and in contact with a molten glass material contained within the furnace. The refractory coating is preferably a flame- or plasma-sprayed ceramic such as alumina or zirconia. That protects the nose member from corrosion from the hot molten glass. | 11-01-2012 |
20130042651 | Methods and Apparatus for Thermally Conditioning Molten Glass - An oblong conduit ( | 02-21-2013 |
20130219968 | GLASS FINING METHOD USING PHYSICAL BUBBLER - A method for fining a glass melt comprises providing a glass melt in a melting vessel, moving the glass melt to a fining vessel via a first channel, and physically introducing gas bubbles to the glass melt in the fining vessel to form a fined glass, wherein the melting vessel and the fining vessel are in a horizontal orientation with respect to each other. | 08-29-2013 |
20140013806 | APPARATUS FOR USE IN DIRECT RESISTANCE HEATING OF PLATINUM-CONTAINING VESSELS - An apparatus for use in controlling a temperature of an oblong-shaped molten glass-carrying vessel, such as a conduit for transporting the molten glass from one location to another location, by flowing a current through the vessel. The apparatus comprises a metal flange comprising a plurality of electrically-conductive rings that include an inner ring joined to the vessel's exterior wall and an outer ring surrounding the inner ring. The inner ring, for example, may include an outer perimeter that is substantially oblong. In some embodiments the inner ring comprises a notch that aids in making current density more uniform. In some examples the width of the inner ring, excluding the notch, does not substantially vary as a function of angular position relative to the vessel. | 01-16-2014 |
20140117017 | STIR CHAMBERS FOR STIRRING MOLTEN GLASS AND HIGH-TEMPERATURE SEALING ARTICLES FOR THE SAME - Stir chambers for stirring molten glass are disclosed. The stir chambers include a support frame, a sealing article, and a removable cover panel. The stir chambers also include a gland coupled to one of the support frame or the removable cover panel, and into which the sealing article is inserted. The stir chambers further include a seal land coupled to one of the support frame or the removable cover panel. The sealing article includes a plurality of ceramic filaments bundled together to form a core portion and a jacket portion that includes a plurality of ceramic filaments woven together. The removable cover panel is coupled to the support frame such that at least a portion of the seal land is positioned inside the gland to compress the sealing article. | 05-01-2014 |
20140230491 | HIGH VOLUME PRODUCTION OF DISPLAY QUALITY GLASS SHEETS HAVING LOW ZIRCONIA LEVELS - Methods and apparatus for producing display quality glass sheets are provided in which the batch materials for making the sheets are melted in a furnace whose glass-engaging surfaces comprise zirconia (ZrO | 08-21-2014 |
Marco De Angelis, Zurich CH
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20130153369 | SPIRAL CONVEYOR - A spiral conveyor has a conveying device that is moved along a helically running spiral region. The conveying device is supported along the spiral region on the radially loaded side of the conveying device. The support is realized by multiple individual deflecting devices that lie along the radially loaded side of the conveying device. Each said deflecting device has a central body including a roller body that surrounds the central body, the roller body including a plurality of rollers. The rollers are rolled on a roller track of the central body in an annular segment of a helically running supporting region of the spiral conveyor. | 06-20-2013 |
Meri De Angelis, Munich DE
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20140147386 | 1-ARYL-4-METHYL-[1,2,4]TRIAZOLO[4,3-a]QUINOXALINE DERIVATIVES - The present invention relates to novel 1-aryl-4-methyl-[1,2,4]triazolo[4,3-a]-quinoxaline derivatives as inhibitors of phosphodiesterase 2 (PDE2) and to a lesser extent of phosphodiesterase 10 (PDE10) or as inhibitors of both, phosphodiesterases 2 and 10. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which PDE2 is involved, or disorders in which both PDE2 and PDE 10 are involved, such as neurological and psychiatric disorders, and endocrinological or metabolic diseases. The present invention also relates to radiolabelled compounds which may be useful for imaging and quantifying the PDE2 enzyme in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo and to precursors of said compounds. | 05-29-2014 |
20140275015 | P2X7 MODULATORS - The present invention is directed to compounds of Formulas (I, IIa and IIb): | 09-18-2014 |
20150322062 | P2X7 MODULATORS - The present invention is directed to compounds of Formulas (I, IIa and IIb): | 11-12-2015 |
20160039809 | P2X7 MODULATORS - The present invention is directed to compounds of Formulas (I, Ia, IIa and IIb). The invention also relates to pharmaceutical compositions comprising compounds of Formulas (I, Ia, IIa and IIb). Methods of making and using the compounds of Formulas (I, Ia, IIa and IIb) are also within the scope of the invention. | 02-11-2016 |
Meri De Angelis, Toledo ES
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20110305637 | RADIOLABELLED PDE10 LIGANDS - The present invention relates to novel, selective, radiolabeled PDE10 ligands which are useful for imaging and quantifying the PDE10A enzyme in tissues using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo. | 12-15-2011 |
20120213703 | RADIOLABELLED PDE10 LIGANDS - The present invention relates to novel, selective, radiolabelled PDE10 ligands which are useful for imaging and quantifying the PDE10A enzyme in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo. | 08-23-2012 |
Meri De Angelis, Munchen DE
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20150366873 | COMBINATIONS COMPRISING PDE 2 INHIBITORS SUCH AS 1-ARYL-4-METHYL-[1,2,4]TRIAZOLO-[4,3-A]]QUINOXALINE COMPOUNDS AND PDE 10 INHIBITORS FOR USE IN THE TREATMENT OF NEUROLOGICAL OF METABOLIC DISORDERS - The present invention relates to combinations of phosphodiesterase 2 (PDE2) inhibitors with inhibitors of phosphodiesterase 10 (PDE10). In particular, the invention relates to combinations of 1-aryl-4-methyl-[1,2,4]triazolo[4,3-a]-quinoxaline derivatives which have been found to inhibit phosphodiesterase 2 (PDE2), with inhibitors of phosphodiesterase 10 (PDE10). Particular PDE10 inhibitors are selected from the group of MP-10, PQ-10, TP-10, papaverine, and the compounds disclosed in WO 2011/051324 and in WO 2011/110545. The invention is also directed to pharmaceutical compositions comprising such combinations, to processes for preparing such compositions, to the use of PDE2 inhibitors, in particular of 1-aryl-4-methyl-[1,2,4]triazolo[4,3-a]-quinoxaline derivatives for the potentiation of said PDE10 inhibitors, and to the use of said PDE10 inhibitors for the potentiation of the effect of said PDE2 inhibitors, in particular, 1-aryl-4-methyl-[1,2,4]triazolo[4,3-a]-quinoxaline derivatives, and to the use of such combinations and compositions for the prevention and treatment of disorders in which PDE2 and PDE10 are involved, such as neurological and psychiatric disorders, and endocrinological or metabolic diseases. | 12-24-2015 |
Rocco De Angelis, Schwalbach DE
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20120306898 | SYSTEMS AND/OR METHODS FOR EFFICIENT RENDERING OF BUSINESS MODEL RELATED VECTOR GRAPHICS - Certain example embodiments described herein relate to systems and/or methods for efficient rendering of vector graphics corresponding to business models generated by a business process management (BPM) package. Such graphics may be provided in an Abstract Vector Graphic (AVG) format. In certain example embodiments, graphic images are provided to an AVG generator, along with a renderer fragment file including static code that is independent from the generated graphic but dependent on the target platform. The AVG generator in certain example embodiments produces program logic that is executable on the target device to cause the display of the graphic. | 12-06-2012 |
20130167001 | CREATING HTML/CSS REPRESENTATIONS OF A GEOMETRIC SYMBOL - The invention relates to the creation of a HTML/CSS representation of a geometric symbol by processing ( | 06-27-2013 |
Travis Don De Angelis, Murray, UT US
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20140278512 | HEALTHCARE CLAIM EDITING SYSTEM, METHOD, AND APPARATUS - A medical claim processing system and method comprising generating default rules and custom rules for inspecting healthcare claims, the default rules having general application to every healthcare claim and the custom rules being created to inspect specific requirements imposed by an insurance company or imposed to a medical code; receiving claim information related to a medical service from a healthcare provider; generating healthcare claims based on the received claim information; and inspecting the medical claims according to the default rules and the custom rules. | 09-18-2014 |
Vittorio De Angelis, Schwalbach DE
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20130167001 | CREATING HTML/CSS REPRESENTATIONS OF A GEOMETRIC SYMBOL - The invention relates to the creation of a HTML/CSS representation of a geometric symbol by processing ( | 06-27-2013 |
Vittorio De Angelis, Schwalbach-Hulsweiler DE
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20150128074 | SYSTEM AND METHOD FOR BROWSER SIDE COLORIZING OF ICON IMAGES - A computer system and computer-implemented method colorizes a UI component image on the browser side. A data provider in the system encodes the UI component image into a Base64 character sequence which includes a header part and an image data part; generates Base64 header parts for specified colored versions of the UI component image; and transfers the encoded UI component image and the Base64 header parts for the specified colored versions of the UI component image to a client icon composer. The header part has a fixed amount of characters and the image data part has a variable amount of characters. The client icon composer replaces the header parts of the encoded UI component image with the Base64 header parts for the specified colored versions of the UI component image; and transfers the specified colored versions of the UI component image to a web page/application. | 05-07-2015 |