Davis, NY
Alan D. Davis, Fairport, NY US
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20130126370 | MULTI-COMPARTMENT CONTAINER WITH FRANGIBLE SEAL AND EXTERNAL MEANS FOR APPLYING OPENING FORCE BETWEEN COMPARTMENTS - Disclosed is a multi-compartment container including features that permit the rupture or opening of a seal between compartments to enable mixing of the materials within each compartment, as well as methods for the use and manufacture of such a container. | 05-23-2013 |
Amy L. Davis, Schoharie, NY US
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20090023701 | Cytokine Inhibitors - Disclosed are compounds of formula (I) | 01-22-2009 |
Arthur Davis, Schaghticoke, NY US
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20140268658 | PHOTOMETRICALLY ADJUSTABLE DIFFUSER USING A VARIABLE COMBINATION OF BULK AND SURFACE RELIEF DIFFUSER TECHNOLOGIES, METHODS OF MAKING, AND USE THEREOF - Novel light diffusers that include both bulk and surface diffuser elements are provided. One embodiment includes diffusing elements forming a structured coating on a substantially clear substrate. Another embodiment includes a bulk diffuser with a structured surface. Methods for making and methods of using the light diffusers are also disclosed. | 09-18-2014 |
Arthur J. Davis, Schaghticoke, NY US
Patent application number | Description | Published |
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20140182659 | METHODS FOR OPTIMIZING MATERIALS FOR LENSES AND LENS ARRAYS AND DEVICES THEREOF - This technology relates generally to methods for the fabrication of lenses which include a glass carrier and an at least partially transmissive layer with one or more slope facets coupled together by one or more draft facets on a surface of the glass carrier. This technology also relates to the resulting lenses and systems including lens arrays. These methods eliminate stress deformation in the resulting lenses by the use of a separator between the glass carrier and the at least partially transmissive layer, at least partial curing of the at least partially transmissive layer prior to formation of the slope and draft facets, modified at least partially transmissive layers which have a cure temperature at or below an operating temperature range of the lens, slope and draft facet dimensions which are selected to correspond with an operating temperature range of the lens, or UV-curable at least partially transmissive layers. | 07-03-2014 |
20140196762 | METHODS FOR FORMING OPTIMIZED LENSES ANDDEVICES THEREOF - This technology relates generally to methods for the fabrication of high performance lenses, in particular, lenses including a glass carrier and an at least partially transmissive layer with one or more slope facets coupled together by one of more draft facets on a surface of the glass carrier. The methods involve identifying geometric errors in the slope and draft facets to create correction factors and forming corrected slope and draft facets based on the correction factors. This technology also relates to the resulting lenses and lens arrays. | 07-17-2014 |
Brian Michael Davis, Albany, NY US
Patent application number | Description | Published |
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20100008939 | UNPROCESSED ROLLING CIRCLE AMPLIFICATION PRODUCT - Methods and compositions using unprocessed (i.e., not deliberately or intentionally cleaved, circularized, or supercoiled) rolling circle amplification (RCA) product. | 01-14-2010 |
20110091091 | PROCESS AND SYSTEM FOR ANALYZING THE EXPRESSION OF BIOMARKERS IN CELLS - The invention relates generally to a process of analyzing and visualizing the expression of biomarkers in individual cells wherein the cells are examined to develop patterns of expression by using a grouping algorithm, and a system to perform and display the analysis | 04-21-2011 |
20110206728 | DNA VACCINES, USES FOR UNPROCESSED ROLLING CIRCLE AMPLIFICATION PRODUCT AND METHODS FOR MAKING THE SAME - A method of eliciting an immune response in an organism comprising: providing an unprocessed rolling circle amplification (RCA) product; and administering an effective amount of the unprocessed RCA product to the organism to elicit the immune response, wherein the unprocessed RCA product is prepared from a circular nucleic acid template comprising at least one promoter sequence, and at least one target sequence. A vaccine comprising unprocessed RCA product is also provided and methods for making the same. | 08-25-2011 |
20130052725 | SYSTEM FOR OPTICAL BASED DELIVERY OF EXOGENOUS MOLECULES TO CELLS - A system for delivering exogenous molecules comprises a support for containing cells and exogenous molecules; an infra-red (IR) light source that generates an IR optical beam with an average power density at least greater than 10 | 02-28-2013 |
20140093946 | SYSTEM FOR OPTIMIZING THE INTRODUCTION OF NUCLEIC ACIDS INTO CELLS USING MAGNETIC PARTICLES - An embodiment of a system is provided herein, wherein the system allows for the analysis and selection of numerous experimental conditions to optimize transfection efficiency and cell viability. The system is used for magnetic particle based nucleic acid delivery by optimizing various parameters. The system comprises a control module; an incubation module for incubating magnetic nanoparticle and nucleic acid; a transfection module and an analysis module. | 04-03-2014 |
20140186946 | CELL CARRIER, ASSOCIATED METHODS FOR MAKING CELL CARRIER AND CULTURING CELLS USING THE SAME - A carrier for expansion of pluripotent stem cells is provided, wherein the carrier comprises a substrate comprising one or more outer surfaces, wherein the one or more outer surfaces are modified with gas plasma treatment, and one or more structured indentations on one or more of the outer surfaces. The carrier has a length at least about 0.2 mm, a width at least about 0.2 mm, and a height in a range from about 0.05 mm to 1.2 mm and each of the structured indentations has a major axis in a range from about 0.1 mm to 0.5 mm, a minor axis in a range from about 0.1 mm to 0.5 mm and a depth in a range from about 0.025 mm to about 0.5 mm. A method of making the carrier, and culturing stromal cells using the same carrier are also provided. | 07-03-2014 |
20140356949 | CELL CARRIER, ASSOCIATED METHODS FOR MAKING CELL CARRIER AND CULTURING CELLS USING THE SAME - A carrier for expansion of induced pluripotent stem cells is provided, wherein the carrier comprises a substrate comprising one or more outer surfaces, wherein the one or more outer surfaces are modified with gas plasma treatment, and one or more structured indentations on one or more of the outer surfaces. The carrier has a length at least about 0.2 mm, a width at least about 0.2 mm, and a height in a range from about 0.05 mm to 1.2 mm and each of the structured indentations has a major axis in a range from about 0.1 mm to 0.5 mm, a minor axis in a range from about 0.1 mm to 0.5 mm and a depth in a range from about 0.025 mm to about 0.5 mm. A method of making the carrier, and culturing induced pluripotent stem cells using the same carrier are also provided. | 12-04-2014 |
Bryan D. Davis, New York, NY US
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20100306324 | ANONYMOUSLY AND AUTONOMOUSLY BRIDGING RETURN SYSTEM AND METHOD - A method and arrangement to facilitate a direct, anonymous communication between an owner and a finder regarding an article. | 12-02-2010 |
Douglas Paul Davis, Ballston Spa (saratoga), NY US
Patent application number | Description | Published |
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20100063927 | METHOD AND SYSTEM FOR CLEARING FINANCIAL INSTRUMENTS - A method and system for electronically clearing financial instruments through a clearing system in which a per item cost of clearing instruments varies with the time of day. The method may include the steps of receiving electronic files of items containing data scanned from financial instruments including an amount of each instrument, applying a rule to sort the items by determining, for each of the associated financial instruments, whether the item be stored or forwarded for clearing the instrument without storage. The rule may include a step of determining whether an amount of the instrument exceeds a predetermined value, and if the amount of the instrument exceeds the predetermined value, forwarding the instrument for clearing without storage. If the amount of the instrument does not exceed the first predetermined value, the associated rule may cause the system to store the item representing the instrument for forwarding at a later time when the per item fee for clearing is lower. The threshold amount may vary depending upon the per item fee charged at the time the item is received by the system, in a case where the per item fee charged changes over the course of a business day, and different time intervals may have different threshold amounts. The system may include a control system for receiving the associated electronic files from a scanning device and have a processor programmed to apply a rule to sort the files by determining, for each of the instruments, whether the associated electronic file should be stored or forwarded for clearing, a gateway server for receiving the associated electronic files from the scanning devices and transmitting the files to the control system, and an image export server for receiving the associated electronic files from the control system, converting the files to a preferred format, storing the files in storage, retrieving the files from storage for clearing and transmitting the files to the Federal Reserve for clearing. | 03-11-2010 |
20120136791 | METHOD AND SYSTEM FOR CLEARING FINANCIAL INSTRUMENTS - A method and system for electronically clearing financial instruments through a clearing system in which a per item cost of clearing instruments varies with the time of day. Files of items containing data scanned from financial instruments including an amount of each instrument may be received by a control system that may apply a rule to sort the items by determining whether the item be stored or forwarded for clearing. The rule may include a step of determining whether an amount of the instrument exceeds a predetermined value or meets a certain criteria, and if so, forwarding the instrument for clearing without storage. If the amount of the instrument does not exceed the first predetermined value or meet the criteria, the system may store the item for forwarding at a later time when the per item fee for clearing is lower. | 05-31-2012 |
Dustin Wayne Davis, Ballston Lake, NY US
Patent application number | Description | Published |
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20090272821 | METHODS AND SYSTEMS FOR MIXING REACTOR FEED - Methods and systems for a feed injector are provided. The feed injector system includes a plurality of annular channels that are substantially concentric about a longitudinal axis. The plurality of annular channels direct a flow of fluid substantially axially therethrough from a respective source to a reaction zone. The feed injector system also includes a swirl member extending into the fluid flow path defined in at least one of the plurality of annular channels wherein the swirl member is configured to impart a circumferential flow direction to fluid flowing through the at least one annular channel. | 11-05-2009 |
20090272822 | FEED INJECTOR SYSTEMS AND METHODS - A feed injector system comprises substantially concentric channels with one being configured for pneumatically conveying pulverized solid fuel feed from a respective source to a reaction zone and another configured to impart convey a fluid oxidizer stream with and without swirl. | 11-05-2009 |
Eric F. Davis, Vestal, NY US
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20130179528 | USE OF MULTICORE PROCESSORS FOR NETWORK COMMUNICATION IN CONTROL SYSTEMS - Various embodiments of the present invention relate to use of one or more multicore processors for network communication (e.g., Ethernet-based communication) in control systems (e.g., vehicle control systems, medical control systems, hospital control systems, instrumentation control systems, test instrument control systems, energy control systems and/or industrial control systems). In one example, one or more systems may be provided with regard to use of multicore processor(s) for network communication (e.g., Ethernet-based communication) in control systems. In another example, one or more methods may be provided with regard to use of multicore processor(s) for network communication (e.g., Ethernet-based communication) in control systems. | 07-11-2013 |
Eric Patrick Davis, Niskayuna, NY US
Patent application number | Description | Published |
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20150099948 | FLEXIBLE EMBEDDED SENSOR ARRAYS AND METHODS OF MAKING THE SAME - A flexible embedded sensor array includes a first substrate, an electrically conductive pad disposed on at least a portion of the first substrate, and a plurality of sensors disposed on at least a portion of electrically conductive pads. Further, the flexible embedded sensor array includes an electrically non-conductive adhesive material disposed in proximity to one or more of the plurality of sensors, a second substrate, and an electrical contact disposed between at least a portion of the sensor and at least a portion of the second substrate. | 04-09-2015 |
Faith B. Davis, West Sand Lake, NY US
Patent application number | Description | Published |
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20090298058 | Inhibitors of PGHS-2Transactivator Activity - Prostaglandin-endoperoxide H synthase (PGHS-2) converts arachidonic acid to prostaglandin H | 12-03-2009 |
20100112079 | Thyroid Hormone Analogs and Methods of Use - Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric form of thyroid hormone, or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed. | 05-06-2010 |
20100159021 | Small Molecule Ligands of the Integrin RGD Recognition Site and Methods of Use - Provided herein are compositions and methods for treating cancer by increasing the pro-apototic actions of small molecule ligands of integrin RGD recognition sites such as polyphenols by administering such compounds in conjunction with anti-angiogenic thyroid hormone analogs such as tetrac or triac. | 06-24-2010 |
20100255108 | Combination Treatment of Cancer With Cetuximab and Tetrac - Provided herein are compositions and methods for treating cancer by increasing the inhibitory effect of cetuximab on HIF1α expression by administering cetuximab in combination with anti-angiogenic thyroid hormone analogs such as tetrac or triac. | 10-07-2010 |
20110052715 | NANOPARTICLE AND POLYMER FORMULATIONS FOR THYROID HORMONE ANALOGS, ANTAGONISTS, AND FORMULATIONS AND USES THEREOF - Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric nanoparticle form of thyroid hormone agonist, partial agonist or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Nanoparticle forms of thyroid hormone or thyroid hormone analogs as well as uses thereof are also disclosed. | 03-03-2011 |
20140072635 | THYROID HORMONE ANALOGS AND METHODS OF USE - Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric form of thyroid hormone, or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed. | 03-13-2014 |
20140072646 | THYROID HORMONE ANALOGS AND METHODS OF USE - Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric form of thyroid hormone, or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed. | 03-13-2014 |
20140314665 | NANOPARTICLE AND POLYMER FORMULATIONS FOR THYROID HORMONE ANALOGS, ANTAGONISTS, AND FORMULATIONS THEREOF - Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric Nanoparticle form of thyroid hormone agonist, partial agonist or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed. | 10-23-2014 |
Faith B. Davis, Latham, NY US
Patent application number | Description | Published |
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20140199376 | NANOPARTICLE AND POLYMER FORMULATIONS FOR THYROID HORMONE ANALOGS, ANTAGONISTS, AND FORMULATIONS THEREOF - Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric Nanoparticle form of thyroid hormone agonist, partial agonist or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed. | 07-17-2014 |
Gary Davis, Albany, NY US
Patent application number | Description | Published |
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20090239435 | PROTECTIVE SUIT AND METHODS OF MANUFACTURE THEREOF - The present disclosure is directed to a composite material comprising one or more layers that are able to bind and deactivate chemical and/or biological agents. The first layer comprises a porous polymer substrate and a nucleophilic organic polymer cross-linked on the surface or within the pores of the porous polymer substrate using a carbamate cross-linking agent, wherein the cross-linked nucleophilic polymer comprises functional groups operative to form a covalent bond with a chemical or biological agent. The composite material is used to manufacture items of protective apparel including chemical-biological protective suits. | 09-24-2009 |
20130004887 | HOLOGRAPHIC RECORDING MEDIUM - Disclosed herein are novel nitrone compounds, holographic recording media that include the nitrone compound(s) and a polymer binder, a method of manufacturing a holographic recording medium where the nitrone compound, as a photochromic dye, is mixed with a polymer binder to form a holographic composition and molding the holographic composition into holographic data recording medium. Disclosed herein too is a method for recording a hologram by exposing the holographic recording medium to mutually coherent signal and reference light sources at a wavelength that causes a change in the chemical structure of the nitrone compound. | 01-03-2013 |
20130071773 | HOLOGRAPHIC STORAGE MEDIUM - Disclosed herein are novel amidic nitrone and a method of manufacturing a data storage media comprising mixing the amidic nitrone, as a photochromic dye, with an organic material or an inorganic material to form a holographic composition and molding the holographic composition into holographic data storage media. Disclosed herein too is an article comprising a photochromic dye and an organic material, wherein the article is used as a data storage media. Disclosed herein too is a method for recording information comprising irradiating an article that comprises a photochromic dye, wherein the irradiation is conducted with electromagnetic energy having a wavelength of about 350 to about 1,100 nanometers; and reacting the photochromic dye. | 03-21-2013 |
Gary C. Davis, Albany, NY US
Patent application number | Description | Published |
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20080312373 | POLYCARBONATE-POLY(ALKYLENE OXIDE) COPOLYMER COMPOSITIONS AND ARTICLES FORMED THEREFROM - Disclosed herein is a polycarbonate copolymer comprising A) a structure derived from a dihydroxy alkylene oxide compound selected from the group consisting of formula (1a) and formula (1b): | 12-18-2008 |
20080312374 | POLYCARBONATE-POLY(ALKYLENE OXIDE) COPOLYMER COMPOSITIONS AND ARTICLES FORMED THEREFROM - Disclosed herein is a polycarbonate copolymer comprising A) a structure derived from a dihydroxy alkylene oxide compound selected from the group consisting of formula (1a) and formula (1b): | 12-18-2008 |
Gary Charles Davis, Albany, NY US
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20090069512 | COMPOSITION AND ASSOCIATED METHOD - A composition includes a reaction product of a poly(arylene ether) composition having a plurality of terminal groups and a siloxane composition. Associated article and method are also provided. | 03-12-2009 |
20090117367 | ARTICLE AND ASSOCIATED METHOD - An article includes a membrane having pores and a selectively permeable coating supported by the membrane. The selectively permeable coating includes a hydroxyalkyl-substituted polyalkyleneimine in an amount that is sufficient to chemically react with a chembio agent to reduce the biological activity of the chembio agent or increase an amount of time for a significant amount of unreacted biologically active chembio agent to pass through the article. An associated method is also provided. | 05-07-2009 |
20090205116 | ARTICLE, LAMINATE AND ASSOCIATED METHODS - An article includes a membrane having pores and a selectively permeable coating supported by the membrane. The selectively permeable coating includes an antimicrobial agent in an amount that is sufficient to chemically react with a chemical or microbial agent to reduce the biological activity of the chemical or microbial agent or increase an amount of time for a significant amount of unreacted biologically active chemical or microbial agent to pass through the article. A laminate and methods of providing these are also provided. | 08-20-2009 |
20090325078 | HOLOGRAPHIC RECORDING MEDIUM - A holographic recording medium including an optically transparent substrate is provided. The optically transparent substrate includes an optically transparent plastic material and a photochemically active dye. The optically transparent substrate has an absorbance of greater than 1 at a wavelength that is in a range of from about 300 nanometers to about 1000 nanometers. The holograms recorded in the optically transparent substrate are capable of having diffraction efficiencies of greater than about 20 percent. The holographic recording medium may include a photo-product. A method of making the holographic recording medium, an optical writing and reading method, a method for using a holographic recording article, and a method of manufacturing the holographic recording medium are provided. | 12-31-2009 |
20100009269 | HOLOGRAPHIC RECORDING MEDIA - A holographic recording medium includes an optically transparent substrate. The optically transparent substrate includes an optically transparent plastic material, a photochemically active dye, and a protonated form of the photochemically active dye. The protonated form of the photochemically active dye is a composition having a structure as shown in formula I | 01-14-2010 |
20100010262 | COMPOSITIONS AND METHOD FOR MAKING THEREOF - A composition has a structure as shown in formula I: | 01-14-2010 |
20100077529 | ARTICLE, LAMINATE AND ASSOCIATED METHODS - An article includes a porous membrane having pores, a first selectively permeable coating supported by the membrane and a component protective against delamination of the selectively permeable coating from the porous membrane and/or any other coatings applied thereto. The first selectively permeable coating includes an antichemical, antibiological, antiradiological and/or antimicrobial agent. The protective component may be provided alone, or as an element of the first selectively permeable coating, or, a second selectively permeable coating. A laminate and methods of providing these are also provided. | 04-01-2010 |
20110242729 | Monomers for preparing polycarbonate resins, methods of preparing the monomers, polycarbonate resins prepared with the monomers, and capacitors comprising the polycarbonate resins - A monomer and polycarbonate resin are provided, as are methods of making the monomer. The resin may be used to provide a thin film that has a higher dielectric constant and higher glass transition temperature, and similar breakdown strength and similar dissipation factor to films prepared from polycarbonate resins not so modified. The thin films, in turn, may advantageously be used to form, wholly or in part, articles such as capacitors, sensors, batteries, flexible printed circuit boards, keyboard membranes, motor/transformer insulations, cable wrappings, industrial tapes, interior coverage materials, and the like. In particular, a capacitor comprising the polycarbonate resin is also provided. | 10-06-2011 |
20120135658 | PROTECTIVE ARTICLE AND METHODS OF MANUFACTURE THEREOF - An article comprises a first layer which includes a substrate and a nucleophilic organic polymer cross-linked on a surface of or within the substrate. The cross-linked nucleophilic polymer comprises functional groups operative to form a covalent bond with a chemical or biological agent. The first layer also includes reactive particles located on a surface of or within the substrate. | 05-31-2012 |
Gary Martin Davis, Rochester, NY US
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20080270252 | DIRECTING POST-SALE SUPPLIES REVENUE TO ORIGINAL DEALER - A method and system of marketing a consumable may include alerting a customer, via a printer status application, to the status of a consumable in a printing device. A printer identifier may be identified for the printing device via the printer status application. Information about a plurality of product selling entities and associations between each entity and one or more printer identifiers may be maintained in a computer-readable medium. The product selling entity that corresponds to the printer identifier may be determined. The customer may be directed to the product selling entity. | 10-30-2008 |
George B. Davis, Brooklyn, NY US
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20150058336 | PERSONALIZED CONTENT RECOMMENDATIONS - Methods, systems and computer program products for providing personalized educational content recommendations are disclosed. A computer-implemented method may include receiving information describing a body of content, receiving data describing an interaction of a user with one or more elements of the body of content, receiving a context that includes one or more criteria associated with the body of content, generating a list of modules from the body of content based on the data describing the interaction of the user with the one or more elements of the body of content in view of the context, and providing the generated list of modules to an interested party. | 02-26-2015 |
Howard Davis, Brooklyn, NY US
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20090308228 | Musical note speedometer - An electronic device that receives a signal indicative of the sound made my a musical instrument in order to determine the instantaneous rate of play of melodic notes on that instrument in terms of notes played per second and display the rate in real time via a display. The regularity of the musician's rate of play is further indicated by the stability of the display reading. Individual sustained melodic notes are identified utilizing differential capacitance and circuit delay time constants to generate a voltage differential in response to a step signal. The device is also selectively operable as a conventional metronome to provide an exemplary sound cue to the musician corresponding to a given number of notes per second and convertible by a switch or foot pedal to monitor the musicians rate of play as he tries to match the demonstrated rate. | 12-17-2009 |
Jason Davis, New York, NY US
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20110066662 | System and Method for Content Extraction from Unstructured Sources - A system and method for extracting content from unstructured sources is disclosed. The method includes analyzing web pages of a website, storing text and image data for each web page of the website, extracting a plurality of entities from the web page data, scoring each entity of the plurality of entities to provide an overall score for each entity, and defining a product based on the plurality of entities and the overall score for each entity. | 03-17-2011 |
Jason L. Davis, Albany, NY US
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20110312967 | BRIDGED AND FUSED ANTIDIABETIC COMPOUNDS - This invention provides for certain bridged and fused compounds of the formula G-L-A I or a pharmaceutically acceptable salt, ester of solvate thereof wherein: A is: (I) and the other variables are defined herein; the inventive compounds are agonists of the G-protein coupled receptor 40 (GPR40, also known as free fatty acid receptor FFAR). This invention further relates to pharmaceutical compositions containing these compounds, and the use of these compounds to regulate insulin levels in a mammal. The compounds may be used, for example in the prevention and treatment of Type 2 diabetes mellitus and in the prevention and treatment of conditions related to Type 2 diabetes mellitus, such as insulin resistance, obesity and lipid disorders. | 12-22-2011 |
20110312995 | BRIDGED AND FUSED HETEROCYCLIC ANTIDIABETIC COMPOUNDS - This invention provides for certain bridged and fused heterocyclic compounds of the formula (I) or a pharmaceutically acceptable salt, ester solvate or prodrug thereof wherein: L is: (II) and the other variables are defined herein; the inventive compounds are agonists of the G-protein coupled receptor 40 (GPR40, also known as free fatty acid receptor FFAR). This invention further relates to pharmaceutical compositions containing these compounds, and the use of these compounds to regulate insulin levels in a mammal. The compounds may be used, for example in the prevention and treatment of Type 2 diabetes mellitus and in the prevention and treatment of conditions related to Type 2 diabetes mellitus, such as insulin resistance, obesity and lipid disorders. | 12-22-2011 |
20110313008 | PENTAFLUOROSULPHOLANE-CONTAINING ANTIDIABETIC COMPOUNDS - This invention provides for certain pentafluorosulpholane-containing compounds of the formula or a pharmaceutically acceptable salt, ester, solvate or prodrug thereof, wherein the variables are defined herein; the inventive compounds are agonists of the G-protein coupled receptor 40 (GPR40, also known as free fatty acid receptor FFAR). This invention further relates to pharmaceutical compositions containing these compounds, and the use of these compounds to regulate insulin levels in a mammal. The compounds may be used, for example in the prevention and treatment of Type 2 diabetes mellitus and in the prevention and treatment of conditions related to Type 2 diabetes mellitus, such as insulin resistance, obesity and lipid disorders. | 12-22-2011 |
20120004234 | PHTHALAZINE-CONTAINING ANTIDIABETIC COMPOUNDS - This invention provides for certain phthalazine-containing compounds of the formula (I) or a pharmaceutically acceptable salt, ester or solvate thereof, wherein G is an optionally substituted N—N containing heteroaryl group and the variables are defined herein; the inventive compounds are agonists of the G-protein coupled receptor 40 (GPR40, also known as free fatty acid receptor FFAR). This invention further relates to pharmaceutical compositions containing these compounds, and the use of these compounds to regulate insulin levels in a mammal. The compounds may be used, for example in the prevention and treatment of Type 2 diabetes mellitus and in the prevention and treatment of conditions related to Type 2 diabetes mellitus, such as insulin resistance, obesity and lipid disorders. | 01-05-2012 |
20140038970 | BRIDGED AND FUSED ANTIDIABETIC COMPOUNDS - This invention provides for certain bridged and fused compounds of the formula | 02-06-2014 |
Jason Louis Davis, Albany, NY US
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20130012493 | NOVEL SPIRO IMIDAZOLONE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE - The present invention relates to compounds of the general formula (I): wherein ring A, ring B, G, R | 01-10-2013 |
20130052109 | COMPOSITIONS FOR ABSORBING CARBON DIOXIDE, AND RELATED PROCESSES AND SYSTEMS - A carbon dioxide absorbent is disclosed. The absorbent compostion contains a liquid, non-aqueous, silicon-based material, functionalized with one or more groups that reversibly react with CO | 02-28-2013 |
20130289257 | FORMULATIONS FOR NUCLEIC ACID STABILIZATION ON SOLID SUBSTRATES - The present disclosure generally relates to dry solid matrices for the extraction, stabilization, and storage of nucleic acids, particularly RNA, in a dry format under ambient conditions for a prolonged period of time. Methods for collecting and recovering the nucleic acids stored in the dry solid matrix are also described. | 10-31-2013 |
Jean Davis, Centerport, NY US
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20110004483 | Systems for applying quantitative marketing research principles to qualitative internet data - An online marketing research system is provided that allows users to monitor the sentiment of their brand via existing data on the internet. Users identify the specific brand and competitive brands in which they are interested. After selecting one of the system's sampling methods, or creating a sampling method unique to their needs, the internet crawler is sent out to select according to the plan a specified number of sentiments. The engine cleans the results of poor quality data such as astro-turfing and re-blogging. The sentiments are then scored using the system's sentiment engine, and further cleaned with the hate and profanity engine. The system's crawling engine also gathers data for competitive brands within the same subcategory, category and industry as well as a variety of unrelated brands. Clients use the system's engine interface to visualize the data in an appealing qualitative format. In addition, they use the system's interactive sentiment modeler to gain more detailed and quantified insights into the data. The interactive sentiment modeler interface allows users to select the types of charts, the constructs, and timelines that are important to them. Users can also select which competitive brands they wish to monitor, as well as which norms they are interested in. When users are satisfied with the charts they have viewed and prepared, they can share, save, and print their results, or set up automated alerts that will inform them when online sentiment has changed. | 01-06-2011 |
Jeffrey Scott Davis, Corning, NY US
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20140144571 | METHOD FOR BONDING ZIRCON SUBSTRATES - Disclosed herein are methods for bonding refractory substrates, such as zircon substrates, without the use of a bonding agent. Exemplary methods include (a) providing a plurality of refractory components, each component having at least one surface to be bonded, (b) polishing each surface to be bonded to a surface roughness (R | 05-29-2014 |
Jennifer Ann Davis, Highland Mills, NY US
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20080299668 | DETECTION AND QUANTITATION OF CALICHEAMICIN - The present invention provides a method of detecting the presence of the calicheamicin component of a calicheamicin-carrier conjugate in a fluid sample, wherein the calicheamicin is covalently bound to the carrier. A bond between the calicheamicin and carrier is disrupted, the calicheamicin portion is released from the calicheamicin-carrier conjugate and detected. | 12-04-2008 |
Jeremy Davis, New York, NY US
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20150074961 | CURTAIN CLIP - We provide a securement apparatus or clip including a flexible unibody member that allows two sides of the clip to be separated, allowing the clip to be placed around a rod to support a curtain. Each part of the clip that is in contact with the rod includes a point of minimal contact with the rod, designed to reduce friction and to help maintain the clip on the rod. | 03-19-2015 |
John D. Davis, Maybrook, NY US
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20110304370 | PROGRAMMABLE CONTROL CLOCK CIRCUIT INCLUDING SCAN MODE - A programmable clock control circuit includes a base block configured to control operation of the programmable clock control circuit and a chop block configured to control the width of an output clock signal of the programmable clock control circuit. The circuit also includes a pulse width variation block providing a pulse width variation output to the base block, the base block output being variable to provide at least three different output pulse widths. The circuit also includes a launch clock delay block coupled to delay the output of the base block and a scan clock delay block to delay the output pulse and a selector that causes either the scan clock delay block or the launch clock delay block to be active based on a value of a scan gate signal. | 12-15-2011 |
20110317496 | JAM LATCH FOR LATCHING MEMORY ARRAY OUTPUT DATA - A jam latch device for a data node includes a feed forward inverter having an input coupled to the data node; a feedback inverter having an input connected to an output of the feed forward inverter with an output of the feedback inverter connected to the data node; an isolation device that selectively decouples the feedback inverter from a power supply rail, the isolation device controlled by a clock signal of a reset device that resets the data node to a first logic state such that decoupling of the feedback inverter from the power supply rail coincides with resetting the data node to the first logic state; and a margin test device that selectively increases pull down strength of the feedback inverter. | 12-29-2011 |
20110317499 | SPLIT VOLTAGE LEVEL RESTORE AND EVALUATE CLOCK SIGNALS FOR MEMORY ADDRESS DECODING - A method of implementing voltage level shifting for a memory device includes coupling one or more evaluation clock signals to a memory address decode circuit, the one or more evaluation clock signals operating at a first voltage supply level; and coupling a restore clock signal to the memory address decode circuit, the restore clock signal operating at a second voltage supply level that is higher than the first voltage supply level; wherein one or more outputs of the memory address decode circuit operate at the second voltage supply level. | 12-29-2011 |
20110317505 | INTERNAL BYPASSING OF MEMORY ARRAY DEVICES - An output control circuit for a memory array includes a latched output node precharged to a first logic state prior to both a read and write operation; first logic that couples memory cell data from a memory read path to the output node during the read operation, the first logic controlled by a timing signal; second logic that internally bypasses the memory read path during a write operation by decoupling it from the output node, such that a logical derivative of write data written to the memory array is also coupled to the output node, the second logic also controlled by the timing signal; and wherein a transition of the output node from the first logic state to a second logic state during the write operation occurs within a time range as that of the same transition during the read operation. | 12-29-2011 |
20110320851 | PORT ENABLE SIGNAL GENERATION FOR GATING A MEMORY ARRAY DEVICE OUTPUT - A method of generating a dynamic port enable signal for gating memory array data to an output node includes generating a programmable leading edge clock signal derivation of an input dynamic clock signal; generating a programmable trailing edge clock signal derivation of the input dynamic clock signal, wherein the leading edge clock signal derivation and the trailing edge clock signal derivation are independently programmable with respect to one another; and gating the generated programmable leading and trailing edge clock signal derivations with a static input enable signal so as to generate the port enable signal such that, when inactive, the port enable signal prevents early memory array data from being coupled to the output node. | 12-29-2011 |
John D. Davis, Wallkill, NY US
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20080247245 | WRITE CONTROL METHOD FOR A MEMORY ARRAY CONFIGURED WITH MULTIPLE MEMORY SUBARRAYS - Write control circuitry and control method are provided for a memory array configured with multiple memory subarrays. The write control circuitry includes multiple subarray write controllers associated with the multiple memory subarrays, each subarray write controller selectively enabling a local write control signal to its associated memory subarray. The selectively enabling is responsive to a received subarray select signal, wherein only one subarray select signal is active at a time. At least some subarray write controllers are powered at least in part via a switched power node, wherein powering of the switched power node is distributively implemented among the subarray write controllers. In one example, the distributively implemented powering of the switched power node is accomplished via multiple inverters distributed among the subarray write controllers, each inverter having an output coupled to the switched power node, and an input coupled to receive a global write enable signal. | 10-09-2008 |
20140078833 | INCREASING MEMORY OPERATING FREQUENCY - A memory apparatus includes a plurality of memory arrays, each memory array including a plurality of memory cells. The apparatus includes a plurality of global bit lines and each one of the global bit lines is connected to a plurality of local bit lines, which are in turn connected to a plurality of memory cells. The apparatus includes a plurality of global bit line (GBL) latches and each GBL latch is located along a separate global bit line to latch a signal along the respective global bit line. The apparatus further includes a plurality of solar bit lines configured to connect the global bit lines to an output latch via a plurality of logic gates. | 03-20-2014 |
20140082390 | CACHE ARRAY WITH REDUCED POWER CONSUMPTION - Embodiments of the disclosure include a cache array having a plurality of cache sets grouped into a plurality of subsets. The cache array also includes a read line configured to receive a read signal for the cache array and a set selection line configured to receive a set selection signal. The set selection signal indicates that the read signal corresponds to one of the plurality subsets of the cache array. The read line and the set selection line are operatively coupled to the plurality of cache sets and based on the set selection signal the subset that corresponds to the set selection signal is switched. | 03-20-2014 |
20150019890 | CACHE ARRAY WITH REDUCED POWER CONSUMPTION - Embodiments of the disclosure include a cache array having a plurality of cache sets grouped into a plurality of subsets. The cache array also includes a read line configured to receive a read signal for the cache array and a set selection line configured to receive a set selection signal. The set selection signal indicates that the read signal corresponds to one of the plurality subsets of the cache array. The read line and the set selection line are operatively coupled to the plurality of cache sets and based on the set selection signal the subset that corresponds to the set selection signal is switched. | 01-15-2015 |
John D. Davis, Walkill, NY US
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20140078835 | HIGH FREQUENCY MEMORY - Embodiments of the disclosure include a high frequency write through memory device including a plurality of memory cells and a plurality of local evaluation circuits. Each of the plurality of local evaluation circuits are coupled to at least one of the plurality of memory cells and are configured to prevent data stored in the coupled memory cells from being written to a latch node during a write through operation. | 03-20-2014 |
John G. Davis, Vestal, NY US
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20100243312 | EQUIPMENT CONTAINER RETENTION AND BONDING SYSTEM AND METHOD - An equipment container retention and bonding system including a dagger pin block assembly that includes a mounting dagger pin and a bonding member formed of a compressive electrically conductive material that is retained on a surface of the dagger pin block assembly wherein the bonding member is compressed between the contact surface on the equipment container and the dagger pin block assembly when the fastening mechanism secures the equipment container in the mounting tray to form an EMI/EMC bonding connection between the mounting tray and the equipment container having an electrical resistance of less than 2.5 milli-ohms under vibration and other loading conditions encountered during use of the system. | 09-30-2010 |
John Paul Davis, Duanesburg, NY US
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20120025529 | System and Methods for Monitoring Oil Conditions of a Wind Turbine Gearbox - A method for monitoring the condition of oil contained within a gearbox of a wind turbine is disclosed. The method generally includes receiving a signal corresponding to a measurement of an oil parameter of the gearbox, comparing the measurement to a predetermined limit for the oil parameter, assigning a severity level based on the comparison of the measurement to the predetermined limit and determining a recommended course of action for the wind turbine based on the severity level. | 02-02-2012 |
20120025538 | UNITARY SUPPORT FRAME FOR USE IN WIND TURBINES AND METHODS FOR FABRICATING SAME - A support frame for use in a wind turbine including a tower and a rotor that is rotatably coupled to a rotor shaft. The support frame includes an upper portion including an inner surface, an outer surface, and at least one bearing housing that is sized to receive the rotor shaft therethrough. A lower portion is integrally formed with the upper portion and extends from the upper portion. The lower portion includes a support flange that is configured to be coupled to the tower to support the rotor shaft and the rotor from the tower. | 02-02-2012 |
20130259684 | SYSTEMS AND METHODS FOR ATTENUATING NOISE IN A WIND TURBINE - A wind turbine having an attenuating unit is presented. One embodiment of the wind turbine includes a tower and a power unit disposed at a first end of the tower. The wind turbine further includes the attenuating unit that is operatively coupled to at least one of the tower and the power unit and configured to attenuate at least the portion of the vibrational bending waves having a frequency above a threshold frequency to reduce the tonal noise of the wind turbine. | 10-03-2013 |
John Sidney Davis, New York, NY US
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20080208615 | Methods and Apparatus for Performing Task Management Based on User Context - Task management techniques based on user context are provided. More particularly, techniques are presented for calculating task attribute values based on user context data. Once task attributes of a user have been determined, the tasks can be prioritized and a suggestion can be made to the user to perform the tasks in the given order. In a first aspect of the invention, a computer-based technique for scheduling at least one task associated with at least one user includes obtaining context associated with the at least one user, and automatically determining a schedule for the at least one user to perform the at least one task based on at least a portion of the obtained context and based on one or more task attributes associated with the at least one task. | 08-28-2008 |
Joshua Thomas Davis, Webster, NY US
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20130157237 | Ski Teaching Apparatus and Method - A ski instructional apparatus and method for teaching young children that allows for dry land training of a student on skis. The apparatus includes a pole that the student straddles. The pole has a cross piece that extends behind the students legs and beneath the buttocks and handlebars for the student to hold onto. Pulling the pole forward causes the cross piece to push the student from behind so little or none of the student's arm strength is needed to pull the student on skis along a dry surface. The tips of the skis are connected by a tether and a line attached to the tether is connected to the pole. The arrangement allows the instructor to move the student forward and, at the same time, to move the ski tips one towards the other or allow the tips to move apart by respectively raising or lowering the pole. | 06-20-2013 |
Judianne Davis, East Setauket, NY US
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20090081128 | Model of Alzheimer's Disease - A modified non-human warm-blooded vertebrate animal in which a biologically active human APP polypeptide is expressed, and in which function of its inducible Nitric Oxide Synthase (iNOS) protein is reduced as compared to a non-modified animal, methods of making the animal, and methods of testing a candidate composition for activity in the treatment of Alzheimer's Disease using the animal. | 03-26-2009 |
Kevin Davis, Syracuse, NY US
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20110059527 | Active Cell Culture Via Shape Memory - Substrates for cell culture and tissue engineering bioreactors consisting of polymers that change their shape over time under stimulation by temperature change, hydration, degradation, or other means. A method of controlling cell culture using a biodegradable shape memory polymer, wherein shape changes can transfer stresses, strains, or both to adherent or otherwise connected cells such that the mechanical stimulus impacts cell development and the resulting properties of tissues. | 03-10-2011 |
Kieran P. Davis, Cornwall, NY US
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20140367039 | SYSTEMS AND METHODS FOR COMPACTING A CHARGE OF COMPOSITE MATERIAL - Systems and methods for compacting a charge of composite material. These systems and methods may utilize a vacuum compaction device to compact the charge of composite material on a supporting surface. The vacuum compaction device may be reusable and may be configured to define an enclosed volume when positioned on the supporting surface and may include a barrier structure and a sealing structure that is configured to form a fluid seal when compressed between the supporting surface and the barrier structure. The vacuum compaction device also may include a vacuum distribution manifold that is in fluid communication with and configured to selectively apply a vacuum to the enclosed volume. Application of the vacuum to the enclosed volume may decrease a pressure within the enclosed volume and transition the vacuum compaction device from an undeformed configuration to a deformed configuration, thereby compacting the charge of composite material on the supporting surface. | 12-18-2014 |
Leonard Davis, Monroe, NY US
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20140220315 | HIGH-STRETCH ENERGY CURABLE INKS & METHOD OF USE IN HEAT TRANSFER LABEL APPLICATIONS - Provided are energy curable high-stretch inks and coatings for heat transfer labels. The inks and coatings include monofunctional monomers/oligomers, thermoplastic inert resins, and zero or a limited amount of multifunctional monomers/oligomers and exhibit good stretchability and surface resistance, such as scratch resistance and solvent (water, oil) resistance. Also provided are methods of using the high stretch inks in heat-transfer label (HTL) applications. | 08-07-2014 |
Lisa Torché Davis, Chittenango, NY US
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20150080776 | SLING SYSTEM FOR PROVIDING BOTH RELIABLE IMMOBILIZATION AND COMFORT - A sling system for providing both reliable immobilization and comfort is disclosed. The sling system comprises a lightweight elastic sling, a support wedge, and a restraint band for securing the user's hand and/or arm to the support wedge, while at the same time the user's shoulder and arm are supported in the sling. The sling comprises various pleats and darts, such as the shoulder compression pleats, that allow the sling to be form-fitted snuggly and comfortably in cocoon-like fashion around the shoulder, arm, and elbow of the user, thereby securely and comfortably immobilizing the injured or repaired shoulder and/or arm and redistributing the weight of the arm away from the shoulder alone, which may be injured, to the combination of both the shoulder and the torso. | 03-19-2015 |
Michael L. Davis, Amherst, NY US
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20100039220 | RFID READER WITH EMBEDDED ATTACK DETECTION HEURISTICS - The present invention is directed toward secure access control systems. Specifically, a method and system is provided that detects, blocks, and reports attempts to compromise access control systems that utilizes machine readable credentials and reader devices. | 02-18-2010 |
20120036575 | METHOD AND APPARATUS FOR MAKING A DECISION ON A CARD - Method and devices for making access decisions in a secure access network are provided. The access decisions are made by a portable credential using data and algorithms stored on the credential. Since access decisions are made by the portable credential non-networked hosts or local hosts can be employed that do not necessarily need to be connected to a central access controller or database thereby reducing the cost of building and maintaining the secure access network. | 02-09-2012 |
20140013418 | METHOD AND APPARATUS FOR MAKING A DECISION ON A CARD - Method and devices for making access decisions in a secure access network are provided. The access decisions are made by a portable credential using data and algorithms stored on the credential. Since access decisions are made by the portable credential non-networked hosts or local hosts can be employed that do not necessarily need to be connected to a central access controller or database thereby reducing the cost of building and maintaining the secure access network. | 01-09-2014 |
20140049360 | DATA COLLECTION USING A CREDENTIAL - Methods, devices, and systems are provided for optimizing the dissemination of information in various types of systems such as an access control system. More specifically, there are provided herein various mechanisms to provide a modified agent path such that an agent following the modified agent path, may update at least one non-networked reader. The update of the at least one non-networked reader not occurring if the agent follows an unmodified agent path. | 02-20-2014 |
20140053248 | DETECTING AND RESPONDING TO AN ATYPICAL BEHAVIOR - Methods, devices, and systems are provided for optimizing the dissemination of information in various types of systems such as an access control system. More specifically, there are provided herein various mechanisms to provide a modified agent path such that an agent following the modified agent path, may update at least one non-networked reader. The update of the at least one non-networked reader not occurring if the agent follows an unmodified agent path. | 02-20-2014 |
20140173717 | SYSTEM AND METHOD OF SECURE DATA ENTRY - A computational device having a user interface is disclosed, the user interface enables a user to securely enter data into the computational device. In particular, the user interface may include a user input portion and a user output portion. The user input portion may be partitioned into a number of input zones, each having a data value associated therewith that when engaged by a user causes the data value associated with the engaged input zone to be provided as input to the computational device. | 06-19-2014 |
20140320261 | METHOD FOR UPGRADING RFID READERS IN SITU - A reader-enhancing device is proposed which enables an in situ upgrade of readers having limited processing capabilities. The reader-enhancing device includes an emulation module that is capable of generating an output which emulates a first type of credential when the reader-enhancing device receives an input that is not in a format used by the first type of credential. The output generated by the emulation module enables the reader to respond to the input even though the input is not in a format natively supported by the reader. | 10-30-2014 |
20140331286 | EVENT DRIVEN SECOND FACTOR CREDENTIAL AUTHENTICATION - A reader configured to perform dual-factor authentication is provided. The reader is configured to analyze credential data as well as event-based user inputs. The event-based user inputs are received in response to the reader presenting one or more events to a user and monitoring the user's reaction thereto. Utilization of an event-based user input enables the reader to perform dual-factor authentication without necessarily being provided with a keyboard or other advanced user input device. | 11-06-2014 |
Michael Lawrence Davis, Amherst, NY US
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20130117814 | SECURE WIEGAND COMMUNICATIONS - The present invention is directed toward secure access systems. Specifically, a method and system is provided that enhances the security of unidirectional communication protocols used in access control systems, such as the Wiegand protocol. The enhancements may include obfuscation of data, a two-way packet-mode communications, and blind synchronization of pseudo-random number generators. | 05-09-2013 |
20130117827 | SECURE WIEGAND COMMUNICATIONS - The present invention is directed toward secure access systems. Specifically, a method and system is provided that enhances the security of unidirectional communication protocols used in access control systems, such as the Wiegand protocol. The enhancements may include obfuscation of data, a two-way packet-mode communications, and blind synchronization of pseudo-random number generators. | 05-09-2013 |
20130234836 | DIRECTIONAL SENSING MECHANISM AND COMMUNICATIONS AUTHENTICATION - The present invention is directed toward an RFID device that includes a motion sensing mechanism. The motion sensing mechanism is adapted to sense motion of the RFID device and then selectively allow or restrict the RFID device's ability to transmit messages, which may include sensitive data, when the RFID device is placed in an RF field. Thus, the motion sensing mechanism is utilized to control access to data on the RFID device to only instances when the holder of the RFID device moves the RFID device in a predefined sequence of motion(s). | 09-12-2013 |
20140118147 | DIRECTIONAL SENSING MECHANISM AND COMMUNICATIONS AUTHENTICATION - The present invention is directed toward an RFID device that includes a motion sensing mechanism. The motion sensing mechanism is adapted to sense motion of the RFID device and then selectively allow or restrict the RFID device's ability to transmit messages, which may include sensitive data, when the RFID device is placed in an RF field. Thus, the motion sensing mechanism is utilized to control access to data on the RFID device to only instances when the holder of the RFID device moves the RFID device in a predefined sequence of motion(s). | 05-01-2014 |
Owen Davis, New York, NY US
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20080306362 | DEVICE AND SYSTEM FOR MONITORING CONTENTS OF PERSPIRATION - Described are devices and systems for monitoring a content of perspiration. The device comprises a memory storing an index of values corresponding to amounts of a content in perspiration, a detection arrangement detecting the content in the perspiration, a processing unit determining an amount of the content in the perspiration, and a feedback arrangement providing feedback data indicative of a value corresponding to the determined amount. | 12-11-2008 |
Patrick Robert Davis, Glenville, NY US
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20150022036 | ROTOR WITH NON-CYLINDRICAL SURFACE FOR DYNAMOELECTRIC MACHINE - Various embodiments include apparatuses adapted to include a dynamoelectric machine rotor with a modified outer surface. In some embodiments apparatuses include a dynamoelectric machine rotor including a rotor body having a spindle, pole regions, the pole regions having a non-uniform radial distance from an axis of rotation of the rotor to an outer surface of the pole regions and a plurality of slots in the outer surface of the rotor body, the plurality of slots being spaced apart in a circumferential direction of the rotor body, each of the plurality of slots extending in an axial direction of the rotor body. | 01-22-2015 |
Paul Davis, West Sand Lake, NY US
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20100159021 | Small Molecule Ligands of the Integrin RGD Recognition Site and Methods of Use - Provided herein are compositions and methods for treating cancer by increasing the pro-apototic actions of small molecule ligands of integrin RGD recognition sites such as polyphenols by administering such compounds in conjunction with anti-angiogenic thyroid hormone analogs such as tetrac or triac. | 06-24-2010 |
Peter C. Davis, East Aurora, NY US
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20090237247 | REMOTE AREA MONITORING SYSTEM - A Remote Area Monitoring System (RAMS) for detecting movement in a disallowed direction through a passageway (P). The RAMS monitors two volumetric spaces that are established by the system, both of which spaces are defined with respect to depth, width, and height. Both a warning zone and an alarm zone are defined for each space. The warning zone protects against inadvertent incursion into the protected spaces; while the alarm zone protects against intentional intrusions thereinto by movement in the disallowed direction. The RAMS automatically monitors both zones and does not require human vigilance to detect and warn of an incursion or intrusion. Human traffic, in both directions through the zones, is monitored; as well as the movement of objects. Movement of humans is detected using a sensor ( | 09-24-2009 |
20130280476 | OFF-ANGLE LAID SCRIMS - A nonwoven laid scrim includes a carrier and an angled scrim overlying the carrier. The angled scrim includes at least one first assembly of filaments and at least one second assembly of filaments. The nonwoven laid scrim has a main direction and a cross direction, the at least one first assembly of filaments is oriented at a first angle, and the at least one second assembly of filaments is oriented at a second angle. Each of the first and second angles is an off-angle measured relative to the cross direction and the first and second angles have distinct values. The nonwoven laid scrim optionally includes a uni-directional fabric including a plurality of filaments, where the carrier overlies the uni-directional fabric. At least two assemblies of filaments and a first cross direction yarn of the carrier also can define a multi-sided shape with at least three sides. | 10-24-2013 |
20130280477 | OFF-ANGLE LAID SCRIMS - A nonwoven laid scrim includes a first carrier, an angled scrim overlying the carrier, and a second carrier overlying the angled scrim. The angled scrim includes at least one assembly of carbon fiber filaments. The nonwoven laid scrim has a main direction and a cross direction. The at least one assembly of carbon fiber filaments is oriented at an off-angle measured relative to the cross direction. The nonwoven laid scrim optionally includes a uni-directional fabric including a plurality of filaments, where the first carrier overlies the uni-directional fabric. At least two assemblies of filaments and a first cross direction yarn of the carrier also can define a multi-sided shape with at least three sides. | 10-24-2013 |
Peter J. Davis, Skaneateles, NY US
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20130267783 | MEDICAL DIAGNOSTIC INSTRUMENT - A medical diagnostic instrument that enables optical viewing of a target area, includes an optical system disposed within an instrument housing, the optical system including at least one primary optical element disposed along an optical axis. A focusing screen is distally aligned along the optical axis for focusing an image of the target area received from the optical system. The focusing screen enables a user to view the target area without requiring an eyepiece, thereby permitting the caregiver to conduct examinations without requiring intimate contact between the patient and the caregiver. | 10-10-2013 |
Peter K. Davis, Niskayuna, NY US
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20090286952 | METHOD OF FORMING POLYCARBONATE - A method of forming polycarbonate includes the steps of introducing a plurality of reaction components to a reactor operating under melt polymerization conditions and removing ester-substituted phenol from the reactor. The plurality of reaction components include a dihydroxy compound, an ester-substituted diaryl carbonate, and a melt transesterification catalyst. The reaction components are introduced in a plurality of reaction component streams. A first reaction component streams includes a melt transesterification catalyst dissolved or suspended in a liquid carrier containing an ester-substituted phenol. The composition of the first reaction component stream is selected such that ester-substituted phenol is not generated as a reaction product in the first reaction component stream. | 11-19-2009 |
Peter Kennedy Davis, Niskayuna, NY US
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20120156772 | CELL CARRIER AND METHODS OF MAKING - In one example of a carrier for growing adherent cells, comprises one or more surfaces; and one or more relief features on one or more of the surfaces, wherein the carrier has a length at least about 0.2 mm, a width at least about 0.2 mm, and a height in a range from about 0.012 mm to 0.5 mm; and wherein each of the relief features has a height in a range from about 2 to 200 μm, and width in a range from about 20 to 200 μm. | 06-21-2012 |
20130042475 | PANELS AND PROCESSES THEREFOR - Polymer-based materials and processes suitable for producing panels, for example, panels for use in a fan shroud abradable seal of a turbofan engine. Such a process includes introducing constituents of an expandable foam material into a continuous forming apparatus that continuously compounds the constituents into a partially-cured compounded polymeric material, which is then continuously formed with the continuous forming apparatus to produce a continuous form having a constant cross-sectional shape transverse to a continuous forming direction of the continuous forming apparatus. A portion of the continuous form is then deformed to produce a preform, and the preform is cured within a restricted volume to cause the preform to expand and produce the panel. | 02-21-2013 |
20140353868 | METHODS OF USING BORON-CONTAINING ADDITIVES AS SILICON CARBIDE CROSSLINKING AGENTS - The present disclosure generally relates to methods of using boron-containing additives for crosslinking polysilazane green fibers, which are precursors to silicon carbide fibers. These methods provide a controllable process for crosslinking silicon carbide fibers while providing a simple way for the introduction of boron as a sintering aid into the polymer structure. | 12-04-2014 |
20150018448 | METHODS AND APPARATUS FOR CROSSLINKING A SILICON CARBIDE FIBER PRECURSOR POLYMER - The present disclosure generally provides methods and apparatus for efficiently crosslinking silicon carbide fiber precursor polymers with electron beam radiation. The methods and apparatus utilize a platform containing silicon carbide fiber precursor polymer. The temperature of the platform is regulated while the silicon carbide fiber precursor polymer is irradiated to thereby regulate the temperature of the irradiated silicon carbide fiber precursor polymer thereon. In this way, the temperature of the irradiated silicon carbide fiber precursor polymer is regulated via the platform both during and after it is subjected to radiation. At least one of the platform and the e-beam radiation mechanism may be translated with respect to the other to irradiate different portions of the silicon carbide fiber precursor polymer and, ultimately, the entirety of the silicon carbide fiber precursor polymer contained on the platform. | 01-15-2015 |
Raphael Davis, Port Jefferson, NY US
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20140294770 | COMPOSITIONS AND METHODS FOR SPINAL DISC REPAIR AND OTHER SURGICAL AND NON-SURGICAL INDICATIONS - The present invention features, inter alia, biocompatible compositions that include a poloxamer and one or more additives such as hyaluronic acid, gelatin, fibronectin, or a peptide fragment of fibronectin. The compositions are useful in tissue repair or remodeling, including repair of an injured spinal disc, in drug delivery, in cell culture, and in inhibiting the formation of adhesions. | 10-02-2014 |
Raphael P. Davis, Port Jefferson, NY US
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20140352039 | NECK PROTECTION DEVICE - A device for use with a helmet in contact sports, which includes a curved body connected with the helmet and configured for disposal along a front part of a user's neck. The body includes: (i) planar first and second surfaces, the first surface having a curved portion to generally conform under the user's chin; and (ii) a third surface that is curved along the front part of the user's neck and configured to be spaced from but does not contact the user's neck. The device is configured to absorb an impact force and resist the user's neck from moving forward during a sports collision. Systems and methods are disclosed. | 12-04-2014 |
20150089720 | NECK PROTECTION DEVICE - A device for use with a helmet in contact sports, which includes a curved body connected with the helmet and configured for disposal along a front part of a user's neck. The body includes: (i) planar first and second surfaces, the first surface defining a slot; and (ii) a third surface that is curved along the front part of the user's neck and configured to be spaced from but does not contact the user's neck. The device is configured to absorb an impact force and resist the user's neck from moving forward during a sports collision. Systems and methods are disclosed. | 04-02-2015 |
Regina A. Davis, Waverly, NY US
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20090194588 | PRINTER WITH INTEGRATED RFID DATA COLLECTOR - A RFID printer for printing and determining the quality of RFID record members having transponders is provided. The RFID printer may be used to print RFID record members utilizing a continuous moving web. In particular, a RFID printer includes an integrated RFID data collector such that identifying RFID transponder information may be recorded and associated with a barcode for inventory tracking purposes. An association file created by the RFID printer may be transferred to a manufacturer or retailer brand owner. The association file may be deleted from the RFID printer upon acknowledgment of receipt of the transmitted association file to the manufacturer or retail brand owner. The RFID printer provides methods for determining quality of RFID printed record members. | 08-06-2009 |
20110172805 | Printer with Integrated RFID Data Collector - A RFID printer for printing and determining the quality of RFID record members having transponders is provided. The RFID printer may be used to print RFID record members utilizing a continuous moving web. In particular, a RFID printer includes an integrated RFID data collector such that identifying RFID transponder information may be recorded and associated with a barcode for inventory tracking purposes. An association file created by the RFID printer may be transferred to a manufacturer or retailer brand owner. The association file may be deleted from the RFID printer upon acknowledgment of receipt of the transmitted association file to the manufacturer or retail brand owner. The RFID printer provides methods for determining quality of RFID printed record members. | 07-14-2011 |
20140236338 | Printer With Integrated RFID Data Collector - A RFID printer for printing and determining the quality of RFID record members having transponders is provided. The RFID printer may be used to print RFID record members utilizing a continuous moving web. In particular, a RFID printer includes an integrated RFID data collector such that identifying RFID transponder information may be recorded and associated with a barcode for inventory tracking purposes. An association file created by the RFID printer may be transferred to a manufacturer or retailer brand owner. The association file may be deleted from the RFID printer upon acknowledgment of receipt of the transmitted association file to the manufacturer or retail brand owner. The RFID printer provides methods for determining quality of RFID printed record members. | 08-21-2014 |
Richard Mallory Davis, Scotia, NY US
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20090236088 | Heat Exchanger with Multiple Internal Diverters - The present application provides improved heat exchangers for controlling the rate of flow through the heat exchanger. The heat exchanger includes an inlet coolant box, and an outlet coolant box, wherein the inlet coolant box and the outlet coolant box are separated by a partition, wherein the partition comprises a first diverting device and a second diverting device, and wherein the range of flow rates over which the first diverting device diverts fluid is different then the range of flow rates over which the second diverting device diverts fluid. | 09-24-2009 |
Robert Davis, New York, NY US
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20130202692 | ORGANIC COMPOUNDS - The invention relates to particular substituted heterocycle fused gamma-carbolines, their prodrugs, in free, solid, pharmaceutically acceptable salt and/or substantially pure form as described herein, pharmaceutical compositions thereof, and methods of use in the treatment of diseases involving 5-HT | 08-08-2013 |
20150072964 | NOVEL METHODS - Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals for the treatment of agitation, aggressive behaviors, posttraumatic stress disorder or impulse control disorders. | 03-12-2015 |
20150079172 | ORGANIC COMPOUNDS - The invention relates to particular substituted heterocycle fused gamma-carbolines, their prodrugs, in free, solid, pharmaceutically acceptable salt and/or substantially pure form as described herein, pharmaceutical compositions thereof, and methods of use in the treatment of diseases involving 5-HT | 03-19-2015 |
20150080404 | NOVEL COMPOSITIONS AND METHODS - The present invention relates to use of particular substituted heterocycle fused gamma-carbolines as described herein, in free, pharmaceutically acceptable salt or prodrug form, and pharmaceutical composition comprising the same optionally in combination with one or more agents, for the prophylaxis or treatment of one or more disorders associated with dementia, particularly behavioral or mood disturbances (e.g., agitation/aggression), psychosis, depression and sleep disturbances among others in patients suffering from dementia. | 03-19-2015 |
Robert E. Davis, Fishkill, NY US
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20090152590 | METHOD AND STRUCTURE FOR SEMICONDUCTOR DEVICES WITH SILICON-GERMANIUM DEPOSITS - A method of forming a semiconductor device including forming a second deposit of silicon-germanium on a first deposit of silicon-germanium, the first deposit formed in a conduction terminal region of a substrate of the semiconductor device and having a first percentage of germanium, and the second deposit having a second percentage of germanium that is less than the first percentage and supports forming a silicide deposit on the second deposit. A structure is also provided. | 06-18-2009 |
Robert Edgar Davis, Fishkill, NY US
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20090140395 | EDGE SEAL FOR THRU-SILICON-VIA TECHNOLOGY - One or more multilayer back side metallurgy (BSM) stack structures are formed on thru-silicon-vias (TSV). The multiple layers of metal may include an adhesion layer of chromium on the semiconductor wafer back side, a conductive layer of copper, diffusion barrier layer of nickel and a layer of nobel metal, such as, gold. To prevent edge attack of copper after dicing, the layer of nickel is formed to seal the copper edge. To also prevent edge attack of the layer of nickel after dicing, the layer of gold is formed to seal both the layer of copper and the layer of nickel. | 06-04-2009 |
Robert L. Davis, Rochester, NY US
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20130092100 | APPARATUS FOR SUPPORTING AN ANIMAL WITH A SEATBELT - This invention generally relates to an animal or pet restraint apparatus for supporting an animal in a vehicle. The animal restraint apparatus adapted to engage with a vehicle seatbelt assembly having a waist strap portion and a shoulder strap portion. The apparatus is comprised of a flat tubular body having a tubular passage configured for releasably receiving the seatbelt assembly and a means for releasably engaging the back panel portion of the flat tubular body to the lower chest portion of a pet, avoiding the neck area. The present invention and its embodiments provide a means for safely and comfortably transporting a pet in a vehicle. | 04-18-2013 |
Samuel Davis, New York, NY US
Patent application number | Description | Published |
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20090081217 | Modified Chimeric Polypeptides with Improved Pharmacokinetic Properties - Modified chimeric polypeptides with improved pharmacokinetics are disclosed. Specifically, modified chimeric Flt1 receptor polypeptides that have been modified in such a way as to improve their pharmacokinetic profile are disclosed. Also disclosed are methods of making and using the modified polypeptides including but not limited to using the modified polypeptides to decrease or inhibit plasma leakage and/or vascular permeability in a mammal. | 03-26-2009 |
20090155899 | Modified Chimeric Polypeptides with Improved Pharmacokinetic Properties - Modified chimeric polypeptides with improved pharmacokinetics are disclosed. Specifically, modified chimeric Flt1 receptor polypeptides that have been modified in such a way as to improve their pharmacokinetic profile are disclosed. Also disclosed are methods of making and using the modified polypeptides including but not limited to using the modified polypeptides to decrease or inhibit plasma leakage and/or vascular permeability in a mammal. | 06-18-2009 |
20100221782 | Modified Chimeric Polypeptides With Improved Pharmacokinetic Properties - Modified chimeric polypeptides with improved pharmacokinetics are disclosed. Specifically, modified chimeric Flt1 receptor polypeptides that have been modified in such a way as to improve their pharmacokinetic profile are disclosed. Also disclosed are methods of making and using the modified polypeptides including but not limited to using the modified polypeptides to decrease or inhibit plasma leakage and/or vascular permeability in a mammal. | 09-02-2010 |
20100331527 | Readily Isolated Bispecific Antibodies with Native Immunoglobulin Format - A bispecific antibody format providing ease of isolation is provided, comprising immunoglobulin heavy chain variable domains that are differentially modified in the CH3 domain, wherein the differential modifications are non-immunogenic or substantially non-immunogenic with respect to the CH3 modifications, and at least one of the modifications results in a differential affinity for the bispecific antibody for an affinity reagent such as Protein A, and the bispecific antibody is isolable from a disrupted cell, from medium, or from a mixture of antibodies based on its affinity for Protein A. | 12-30-2010 |
20110028698 | Modified Chimeric Polypeptides with Improved Pharmacokinetic Properties - Modified chimeric polypeptides with improved pharmacokinetics are disclosed. Specifically, modified chimeric Flt1 receptor polypeptides that have been modified in such a way as to improve their pharmacokinetic profile are disclosed. Also disclosed are methods of making and using the modified polypeptides including but not limited to using the modified polypeptides to decrease or inhibit plasma leakage and/or vascular permeability in a mammal. | 02-03-2011 |
20110195454 | Common Light Chain Mouse - A genetically modified mouse is provided, wherein the mouse is incapable of rearranging and expressing an endogenous mouse immunoglobulin light chain variable sequence, wherein the mouse expresses only one or two human light chain variable domains encoded by human immunoglobulin sequences operably linked to the mouse kappa (κ) constant gene at the endogenous mouse κ locus, wherein the mouse expresses a reverse chimeric antibody having a light chain variable domain derived from one of only two human light chain variable region gene segments and a mouse κ constant domain, and a human heavy chain variable domain and a mouse heavy chain constant domain, from an endogenous mouse heavy chain locus. Bispecific epitope-binding proteins that are fully human are provided, comprising two different heavy chains that associate with an identical light chain that comprises a variable domain derived from one of two different human light chain variable region gene segments. | 08-11-2011 |
20120021409 | Common Light Chain Mouse - A genetically modified mouse is provided, wherein the mouse expresses an immunoglobulin light chain repertoire characterized by a limited number of light chain variable domains. Mice are provided that express just one or a few immunoglobulin light chain variable domains from a limited repertoire in their germline. Methods for making light chain variable regions in mice, including human light chain variable regions, are provided. Methods for making human variable regions suitable for use in multispecific binding proteins, e.g., bispecific antibodies, are provided. | 01-26-2012 |
20120064621 | Cell Culture Compositions Capable of Producing a VEGF-Binding Fusion Polypeptide - The present invention provided cell culture compositions capable of producing fusion polypeptides that bind vascular endothelial growth factor (VEGF). The cell culture compositions of the invention comprise cells which contain an expression vector comprising a nucleic acid molecule encoding a fusion polypeptide that binds VEGF. The fusion polypeptides may comprise a VEGF receptor component having immunoglobulin-like (Ig) domain 2 of a first VEGF receptor, an Ig domain 3 of a second VEGF receptor, and a multimerizing component. | 03-15-2012 |
20120192300 | Common Light Chain Mouse - A genetically modified mouse is provided, wherein the mouse expresses an immunoglobulin light chain repertoire characterized by a limited number of light chain variable domains. Mice are provided that express just one or a few immunoglobulin light chain variable domains from a limited repertoire in their germline. Methods for making light chain variable regions in mice, including human light chain variable regions, are provided. Methods for making human variable regions suitable for use in multispecific binding proteins, e.g., bispecific antibodies, are provided. | 07-26-2012 |
20130045492 | Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain - A genetically modified mouse is provided, wherein the mouse expresses an immunoglobulin light chain repertoire characterized by a limited number of light chain variable domains. Mice are provided that express just one or a few immunoglobulin light chain variable domains from a limited repertoire in their germline. Methods for making bispecific antibodies having universal light chains using mice as described herein, including human light chain variable regions, are provided. Methods for making human variable regions suitable for use in multispecific binding proteins, e.g., bispecific antibodies, and host cells are provided. Bispecific antibodies capable of binding first and second antigens are provided, wherein the first and second antigens are separate epitopes of a single protein or separate epitopes on two different proteins are provided. | 02-21-2013 |
20130084635 | Cell Culture Compositions Capable of Producing a VEGF-Binding Fusion Polypeptide - The present invention provides cell culture compositions capable of producing fusion polypeptides that bind vascular endothelial growth factor (VEGF). The cell culture compositions of the invention comprise cells which contain an expression vector comprising a nucleic acid molecule encoding a fusion polypeptide that binds VEGF. The fusion polypeptides may comprise a VEGF receptor component having an immunoglobulin-like (Ig) domain 2 of a first VEGF receptor, an Ig domain 3 of a second VEGF receptor, and a multimerizing component. | 04-04-2013 |
20130149744 | Methods for Producing a Fusion Protein Capable of Binding VEGF - The present invention provides methods for producing a fusion protein capable of binding vascular endothelial cell growth factor (VEGF). The methods of the invention comprise growing recombinant cells in suspension culture, wherein the recombinant cells contain an expression vector comprising a nucleic acid molecule encoding a fusion protein that binds VEGF, and isolating the fusion protein from the suspension culture. The fusion protein may comprise a VEGF receptor component having an immunoglobulin-like (Ig) domain 2 of a first VEGF receptor, an Ig domain 3 of a second VEGF receptor, and a multimerizing component. | 06-13-2013 |
20130185821 | Common Light Chain Mouse - A genetically modified mouse is provided, wherein the mouse expresses an immunoglobulin light chain repertoire characterized by a limited number of light chain variable domains. Mice are provided that express just one or a few immunoglobulin light chain variable domains from a limited repertoire in their germline. Methods for making bispecific antibodies having universal light chains using mice as described herein, including human light chain variable regions, are provided. Methods for making human variable regions suitable for use in multispecific binding proteins, e.g., bispecific antibodies, and host cells are provided. Bispecific antibodies capable of binding first and second antigens are provided, wherein the first and second antigens are separate epitopes of a single protein or separate epitopes on two different proteins are provided. | 07-18-2013 |
20130198879 | Humanized Universal Light Chain Mice - Mice, tissues, cells, and genetic material are provided that comprise a humanized heavy chain immunoglobulin locus, a humanized light chain locus that expresses a universal light chain, and a gene encoding an ADAM6 or ortholog or homolog or functional fragment thereof. Mice are provided that express humanized heavy chains comprising human variable domains, and that express humanized light chains comprising human variable domains wherein the light chains are derived from no more than one, or no more than two, light chain V and J or rearranged V/J sequences. Fertile male mice that express antibodies with universal light chains and humanized heavy chains are provided. Methods and compositions for making bispecific binding proteins are provided. | 08-01-2013 |
20130198880 | MICE EXPRESSING A LIMITED IMMUNOGLOBULIN LIGHT CHAIN REPERTOIRE - A genetically modified mouse is provided, wherein the mouse expresses an immunoglobulin light chain repertoire characterized by a limited number of light chain variable domains. Mice are provided that present a choice of two human light chain variable gene segments such that the immunoglobulin light chains expresses by the mouse comprise one of the two human light chain variable gene segments. Methods for making bispecific antibodies having universal light chains using mice as described herein, including human light chain variable regions, are provided. Methods for making human variable regions suitable for use in multispecific binding proteins, e.g., bispecific antibodies, and host cells are provided. | 08-01-2013 |
20130302836 | COMMON LIGHT CHAIN MOUSE - A genetically modified mouse is provided, wherein the mouse is incapable of rearranging and expressing an endogenous mouse immunoglobulin light chain variable sequence, wherein the mouse expresses only one or two human light chain variable domains encoded by human immunoglobulin sequences operably linked to the mouse kappa (κ) constant gene at the endogenous mouse κ locus, wherein the mouse expresses a reverse chimeric antibody having a light chain variable domain derived from one of only two human light chain variable region gene segments and a mouse κ constant domain, and a human heavy chain variable domain and a mouse heavy chain constant domain, from an endogenous mouse heavy chain locus. Bispecific epitope-binding proteins that are fully human are provided, comprising two different heavy chains that associate with an identical light chain that comprises a variable domain derived from one of two different human light chain variable region gene segments. | 11-14-2013 |
20140155689 | METHODS OF MODIFYING GENES IN EUKARYOTIC CELLS - Methods of creating mutations in genomic exons by inserting introns into the genomic exons via homologous recombination. Also, methods are provided for introducing modifications into genomic exons by inserting introns into the genomic exons via homologous recombination such that a mature mRNA transcript produced from a genomic region of the genome comprising the genomic exon does not contain the modification are provided. The methods provide for a rapid method for introducing mutations and/or modifications of any type into a mammalian cell genome. | 06-05-2014 |
20140194597 | MODIFIED CHIMERIC POLYPEPTIDES WITH IMPROVED PHARMACOKINETIC PROPERTIES - The present invention provides VEGF antagonists with improved pharmacokinetic properties. According to certain embodiments, a fusion polypeptide capable of antagonizing VEGF activity is provided comprising a modified extracellular ligand binding domain of a VEGF receptor fused to a multimerizing component. | 07-10-2014 |
20140243504 | ANTIBODIES COMPRISING CHIMERIC CONSTANT DOMAINS - Antibodies, antigen-binding proteins and Fc-fusion proteins that comprise recombinant polypeptides containing a chimeric heavy chain constant region sequence are provided that bind to certain Fc receptors however have reduced effector functions. Methods of making constructs for expression of such chimeric Fc-containing antibodies, antigen-binding proteins and Fc-fusion proteins in cell systems, and methods of producing and isolating the chimeric Fc-containing proteins are provided. | 08-28-2014 |
20140248664 | READILY ISOLATED BISPECIFIC ANTIBODIES WITH NATIVE IMMUNOGLOBULIN FORMAT - A bispecific antibody format providing ease of isolation is provided, comprising immunoglobulin heavy chain variable domains that are differentially modified in the CH3 domain, wherein the differential modifications are non-immunogenic or substantially non-immunogenic with respect to the CH3 modifications, and at least one of the modifications results in a differential affinity for the bispecific antibody for an affinity reagent such as Protein A, and the bispecific antibody is isolable from a disrupted cell, from medium, or from a mixture of antibodies based on its affinity for Protein A. | 09-04-2014 |
20150059009 | METHODS FOR MAKING FULLY HUMAN BISPECIFIC ANTIBODIES USING A COMMON LIGHT CHAIN - A genetically modified mouse is provided, wherein the mouse expresses an immunoglobulin light chain repertoire characterized by a limited number of light chain variable domains. Mice are provided that express just one or a few immunoglobulin light chain variable domains from a limited repertoire in their germline. Methods for making bispecific antibodies having universal light chains using mice as described herein, including human light chain variable regions, are provided. Methods for making human variable regions suitable for use in multispecific binding proteins, e.g., bispecific antibodies, and host cells are provided. Bispecific antibodies capable of binding first and second antigens are provided, wherein the first and second antigens are separate epitopes of a single protein or separate epitopes on two different proteins are provided. | 02-26-2015 |
Stephen M. Davis, Poughkeepsie, NY US
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20090313639 | SERVICE ORIENTED ARCHITECTURE INFRASTRUCTURE FOR BUSINESS PROCESS VERIFICATION AND SYSTEMS INTEGRATED TESTING - A service oriented architecture (SOA) infrastructure is provided for business process verification and systems integrated testing. The system includes one or more primary agents each dedicated to detecting a particular business process. The system further includes one or more action agents each configured to provide a verification function for the particular business process. Additionally, the system includes a service manager configured to provide context look-up services for the one or more primary agents to determine which action agent of the one or more action agents is responsible for a particular verification function of the particular business process. | 12-17-2009 |
20120266185 | SERVICE ORIENTED ARCHITECTURE INFRASTRUCTURE FOR BUSINESS PROCESS VERIFICATION AND SYSTEMS INTEGRATED TESTING - A service oriented architecture (SOA) infrastructure is provided for business process verification and systems integrated testing. The system includes one or more primary agents each dedicated to detecting a particular business process. The system further includes one or more action agents each configured to provide a verification function for the particular business process. Additionally, the system includes a service manager configured to provide context look-up services for the one or more primary agents to determine which action agent of the one or more action agents is responsible for a particular verification function of the particular business process. | 10-18-2012 |
Steven Davis, Ossining, NY US
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20120323782 | System and Method for Remote Deposit System - Described is a method and system for a remote deposit system. The method comprises receiving facsimile data corresponding to facsimile of a plurality of checks, constructing digitized images of the checks as a function of the facsimile data, gathering check data from each of the digitized images, and processing the check data according to a check processing procedure to settle transactions referenced by each of the checks. | 12-20-2012 |
20130159182 | System and Method for Remote Deposit System - Described is a method and system for a remote deposit system. The method comprises receiving facsimile data corresponding to facsimile of a plurality of checks, constructing digitized images of the checks as a function of the facsimile data, gathering check data from each of the digitized images, and processing the check data according to a check processing procedure to settle transactions referenced by each of the checks. | 06-20-2013 |
Steven Davis, Cheektowaga, NY US
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20090117457 | Electrochemical Cells And Method Of Manufacturing Same - An electrochemical cell comprising a casing, an anode comprising anode active material, a cathode, and an electrolyte solution activating the cathode and the anode is described. In one embodiment, the cathode is comprised of a first current collector, first and second sheets of a first cathode active material in contact with the first current collector, a second current collector, third and forth sheets of the first cathode active material in contact with the second current collector, and a first sheet of a second cathode active material in non-adherent and congruent contact with the second and third sheets of the first cathode active material. | 05-07-2009 |
Steven Davis, Hawthorne, NY US
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20140058942 | SYSTEM AND METHOD FOR REMOTE DEPOSIT SYSTEM - Described is a method and system for a remote deposit system. The method comprises receiving facsimile data corresponding to facsimile of a plurality of checks, constructing digitized images of the checks as a function of the facsimile data, gathering check data from each of the digitized images, and processing the check data according to a check processing procedure to settle transactions referenced by each of the checks. | 02-27-2014 |
Taryn J. Davis, Beacon, NY US
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20140284040 | HEAT SPREADING LAYER WITH HIGH THERMAL CONDUCTIVITY - Embodiments of the invention comprise a homogeneous heat spreading cap element in chip packages to facilitate better heat spreading and dissipation. The heat spreading cap comprises a single high-K graphite layer supported by a copper frame for increased stability and reduced thermal warpage during handling and operation while minimizing thermal penalty by reducing the amount of material having a relatively low heat conductivity that is needed in conventional heat spreading caps. | 09-25-2014 |
Timothty M. Davis, Macedon, NY US
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20110081178 | Waste Cyclone Dispense System with Controlled Rotating Cylinder Gate - This is a waste cyclone toner dispense system with a controlled gate and a collection bag below the gate. The controlled gate prevents pressure from entering the bag thereby permitting the use of relatively inexpensive bags for collection of toner debris. The gate has rotating blades tightly pushed against a sealing wall, such as rubber or the like. The wall must prevent pressure from reaching the bag and remaining only above the bag. The rotating blades convey waste toner from an upper collection to the collection bag. | 04-07-2011 |
Timothy M. Davis, Macedon, NY US
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20110081179 | Waste Cyclone Dispense System With a Controlled Gate - This is a waste cyclone toner dispense system with a controlled gate and a collection bag below the gate. The controlled gate is configured to be opened and closed at a predetermined time thereby permitting the use of relatively inexpensive bags for collection of toner debris. The gate is hinged to permit easy opening by a controller and motor. The controller turns off any pressure while the gate is open. The drop gate conveys when open waste toner from an upper waste collection funnel to the collection bag. | 04-07-2011 |
Wendell Davis, New York, NY US
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20080225779 | LOCATION-BASED NETWORKING SYSTEM AND METHOD - A technique for creating a network model involves receiving location data associated with objects and using the location data to improve the size and/or accuracy of the network model. A technique for creating geo-tagged content involves providing a probable location associated with a client and geo-tagging content at that location. | 09-18-2008 |