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Davidson, MA
Alan J. Davidson, West Roxbury, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090004163 | METHOD OF ENHANCING PROLIFERATION AND/OR HEMATOPOIETIC DIFFERENTIATION OF STEM CELLS - The present invention provides a method for enhancing the proliferation and/or hematopoietic differentiation and/or maintenance of mammalian stem cells. The method is useful for generating expanded populations of hematopoietic stem cells (HSCs) and thus mature blood cell lineages. This is desirable where a mammal has suffered a decrease in hematopoietic or mature blood cells as a consequence of disease, radiation or chemotherapy. The method of the present invention comprises increasing the intracellular level of a cdx in stem cells, including hematopoietic stem cells, in culture, either by providing an exogenous cdx protein to the cell, or by introduction into the cell of a genetic construct encoding a cdx. The cdx is selected from the cdx family and includes cdx1, cdx2, or cdx4. The cdx may be a wild type protein appropriate for the species from which the cells are derived, or a mutant form of the protein. | 01-01-2009 |
| 20100278792 | METHOD OF ENHANCING PROLIFERATION AND/OR HEMATOPOIETIC DIFFERENTIATION OF STEM CELLS - The present invention provides a method for enhancing the proliferation and/or hematopoietic differentiation and/or maintenance of mammalian stem cells. The method is useful for generating expanded populations of hematopoietic stem cells (HSCs) and thus mature blood cell lineages. This is desirable where a mammal has suffered a decrease in hematopoietic or mature blood cells as a consequence of disease, radiation or chemotherapy. The method of the present invention comprises increasing the intracellular level of a cdx in stem cells, including hematopoietic stem cells, in culture, either by providing an exogenous cdx protein to the cell, or by introduction into the cell of a genetic construct encoding a cdx. The cdx is selected from the cdx family and includes cdx1, cdx2, or cdx4. The cdx may be a wild type protein appropriate for the species from which the cells are derived, or a mutant form of the protein. | 11-04-2010 |
David Davidson, Lincoln, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090175818 | Poly(Potassium and Sodium Styrene Sulfonate) Its Manufacture and Its Uses - Antibiotic-associated diarrhea, such as that caused by | 07-09-2009 |
Frank F. Davidson, Sherborn, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100030618 | System and method for visualizing a marketing strategy - A system and method for visualizing a marketing strategy and its effects on a marketplace are disclosed. Using the system or method, an organization can visualize its marketing strategy in a way that links the original creative intent of the marketing strategy with the marketing strategy's effects upon a marketplace. The method and system enable the organization to evaluate the effectiveness of not only its marketing strategy, but of the creative process that led to the marketing strategy's development. The method and system employ representations of creative aspects of the marketing strategy and representations of effects of the marketing strategy on the marketplace, and present, via a graphical user interface, a user-interactive, creative-aspects-based structure, along with the representations of the effects of the marketing strategy, in a manner enabling interaction with the representations of the creative aspects and the effects on the marketplace. | 02-04-2010 |
Marc Davidson, Andover, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090303001 | SYSTEM FOR DETECTING AND COMMUNICATING WITH RFID MEMORY DEVICES - This invention relates to a system of communicating with a radio frequency identification (RFID) transponder microchip (IC) for the purpose of accessing pre-programmed data. Such system involves direct electrical contact between the system reading the data from the memory in the transponder IC and the IC itself via two mechanical contact points. This system provides an interface with a transponder IC in order to energize the IC. Once the presence of the transponder IC is detected, the host system can read or write to and process preprogrammed data stored in the IC. | 12-10-2009 |
| 20100022864 | SKIN PREPARATION DEVICE AND BIOPOTENTIAL SENSOR - The skin preparation device and sensor of the present invention include an array of rigid tines. The tines serve to “self-prepare” the skin at each electrode site. These tines, when pressed against the skin, penetrate the stratum corneum, thereby reducing skin impedance and improving signal quality. A self-prepping device of the present invention is an optimized array of short non-conductive rigid tines in which the individual tines are created in a geometry that allows for a sharp point at the tip when molding, machining or etching is used as a method of fabrication. This non-conductive array with rigid penetrating structures may, therefore, be used in combination with a conductive medium, preferably an ionic conductive gel. In penetrating the stratum corneum, micro-conduits are created in the layers of the skin enabling the conductive medium to reach the low impedance layers and to transmit bioelectrical signals from the skin to the electrode surface. Such a self-prepping device can be readily mass produced using molding methods or possibly other manufacturing methods, thereby providing for a low cost means of achieving improved performance of the biopotential sensor. Additionally this invention includes the integration of this self-prepping device into a biopotential sensor comprising an array of one or more electrodes. | 01-28-2010 |
Scott Davidson, Jamaica Plain, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080246761 | Systems for hybrid geometric/volumetric representation of 3d objects - The invention provides a system for modeling three-dimensional objects using hybrid geometric/volumetric representation, wherein sharp edges are created by a geometric representation that is connected to the volumetric representation. The system creates, maintains, and updates the hybrid representation according to user input. The system also provides for conversion of the hybrid representation into either a wholly geometric representation or a wholly volumetric representation, as may be needed for output to a given device, such as a display device, a printer, and/or a fabricating device. | 10-09-2008 |
| 20090248184 | Haptically enabled dental modeling system - The invention provides a digital dentistry system that utilizes a haptic interface and features a computer-based design application configured to allow the intuitive construction of irregular, amorphous three-dimensional structures typically seen in dental restorations, utilizing, where appropriate, the design skills of a user. In certain embodiments, the system provides a comprehensive digital solution for dental labs in the business of creating dental restorations such as partial frameworks, crowns, copings, bridge frameworks, implants and the like, with a sense of touch provided by a haptic interface device. | 10-01-2009 |
Scott M. Davidson, Chelmsford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090013394 | SYSTEM FOR PROVIDING SINGLE SIGN-ON USER NAMES FOR WEB COOKIES IN A MULTIPLE USER INFORMATION DIRECTORY ENVIRONMENT - A system for providing single sign-on (SSO) user names for Web cookies in a multiple user information directory environment. SSO access to multiple applications is supported in situations where multiple user information directories are deployed, and users may be known by multiple identifiers. Convenient specification is enabled for which of a user's multiple names is to be used in an SSO Web cookie that is passed from application to application to enable SSO operation. The user's SSO Web cookie user name is fully separated conceptually from the user's effective name for any given application within the SSO environment. The SSO Web cookie user name provided by the disclosed system is specified independently from the effective name by which the user is known when operating in the Web application that writes the SSO Web cookie back to the user's computer system. Use of an administratively supplied user name in the SSO Web cookie is facilitated. | 01-08-2009 |
| 20090013395 | METHOD AND SYSTEM FOR PROVIDING SINGLE SIGN-ON USER NAMES FOR WEB COOKIES IN A MULTIPLE USER INFORMATION DIRECTORY ENVIRONMENT - A system for providing single sign-on (SSO) user names for Web cookies. SSO access to multiple applications is supported in situations where multiple user information directories are deployed, and users may be known by multiple identifiers. Convenient specification is enabled for which of a user's multiple names is to be used in an SSO Web cookie that is passed from application to application to enable SSO operation. The user's SSO Web cookie user name is fully separated conceptually from the user's effective name for any given application within the SSO environment. The SSO Web cookie user name provided by the disclosed system is specified independently from the effective name by which the user is known when operating in the Web application that writes the SSO Web cookie back to the user's computer system. Use of an administratively supplied user name in the SSO Web cookie is facilitated. | 01-08-2009 |
Thomas Davidson, Arlington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090011066 | Three-Dimensional Printer - A three-dimensional printer uses inkjet-type printheads to rapidly prototype, or print, a three-dimensional model. A powder feeder includes a conveyor system and a metering system to deliver powder to a build area in measured quantities. The powder feeder also includes a vacuum system for loading powder into a feed reservoir or chamber. The vacuum system can also be used to cleanup excess powder. Other powder control features include powder gutters and magnetic powder plows. During printing, a cleaning system operates to remove powder from the printheads. In the event of a printhead or jet failure, the failure can be detected and corrective measures taken automatically. After printing, the model can be depowdered and infiltrated in an enclosure. | 01-08-2009 |
| 20100151136 | Three-Dimensional Printer - A three-dimensional printer uses inkjet-type printheads to rapidly prototype, or print, a three-dimensional model. A powder feeder includes a conveyor system and a metering system to deliver powder to a build area in measured quantities. The powder feeder also includes a vacuum system for loading powder into a feed reservoir or chamber. The vacuum system can also be used to cleanup excess powder. Other powder control features include powder gutters and magnetic powder plows. During printing, a cleaning system operates to remove powder from the printheads. In the event of a printhead or jet failure, the failure can be detected and corrective measures taken automatically. After printing, the model can be depowdered and infiltrated in an enclosure. | 06-17-2010 |