| Patent application number | Description | Published |
|---|
| 20080274102 | Antibodies to Nik, Their Preparation and Use - An antibody or antibody fragment preparation being capable of specifically binding the amino acid sequence 60-76, 86-98, 135-149, 215-227, 363-377, 385-397, 405-419, 427-440, 509-522, 605-619, 635-649, 666-680, 696-711, 752-766, 836-851, 871-884, and/or 904-916 of NIK, or being capable of specifically binding a specific portion of the amino acid sequence is provided. | 11-06-2008 |
| 20080287356 | Chimeric Proteins, Their Preparation and Pharmaceutical Compositions Containing Them - The present invention relates to a chimeric protein comprising a cell-targeting agent and a | 11-20-2008 |
| 20080311599 | ANTIBODIES AGAINST CASPASE-8, THEIR PREPARATION AND USE - The invention relates to antibodies to a specific region in caspase-8, and to their use. | 12-18-2008 |
| 20090042796 | DERIVATIVES OF THE IL-2 RECEPTOR GAMMA CHAIN, THEIR PRODUCTION AND USE - This invention relates to the use of the IL-2 common gamma (cγc) and related molecules for the modulation of signal activities controlled by NIK, and some new such molecules | 02-12-2009 |
| 20090075889 | IREN PROTEIN, ITS PREPARATION AND USE - There are provided DNA sequences encoding TRAF binding proteins, proteins encoded thereby, and their use in the treatment or prevention of pathological conditions associated with NF-κB induction, or an activity mediated by a TRAF. | 03-19-2009 |
| 20090088558 | TNF RECEPTOR ACTION MODULATION - A method of modulating signal transduction and/or cleavage in Tumor Necrosis Factor Receptors (TNF-Rs) is provided. Peptides or other molecules may interact either with the receptor itself, or with effector proteins interacting with the receptor, thus modulating the normal functioning of the TNF-Rs. Such peptides or other molecules may be employed for prophylactic and therapeutic applications in TNF associated diseases. | 04-02-2009 |
| 20090098106 | PHARMACEUTICAL COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH NF-kB ACTIVITY - A method of treating a disease associated with NF-κB activity. The method is effected by providing to a subject in need thereof a therapeutically effective amount of an agent capable of modulating NIK-HC8 binding. | 04-16-2009 |
| 20090104175 | USE OF CASPASES FOR THE PREPARATION OF MEDICAMENTS - The invention relates to caspases and to extracellular use of caspases for regulating cell functions. | 04-23-2009 |
| 20090269331 | CASPASE-8 AND INFLAMMATION, INFECTION AND WOUND HEALING - The present invention relates to the regulatory role of caspase-8 in infection by intracellular pathogen, inflammation and wound healing | 10-29-2009 |
| 20090291888 | MODULATORS OF TNF RECEPTOR ASSOCIATED FACTOR (TRAF), THEIR PREPARATION AND USE - A DNA sequence encoding a protein capable of binding to a tumor necrosis factor receptor-associated factor (TRAF) molecule, TRAF-binding proteins, their isoforms, analogs, fragments and derivatives encoded by the DNA sequence, their methods for the production of the DNA sequences and proteins, and the uses for the DNA sequence and proteins. | 11-26-2009 |
| 20090297515 | Use of Caspase-8 Inhibitors for Modulating Hematopoiesis - A method of inhibiting hematopoiesis in a subject is provided. The method is effected by downregulating an expression or activity of caspase-8 in the subject thereby inhibiting hematopoiesis therein. | 12-03-2009 |
| 20100204091 | SIVA Ubiquitination and/or Degradation-Related Activity and Modulators Thereof - The present invention relates to the ubiquitination and/or degradation-related activity of a SIVA polypeptide and to agents capable of modulating said activity. | 08-12-2010 |
| 20110035817 | SIVA 3, ITS PREPARATION AND USE - The present invention relates to a splice variant of SIVA, SIVA3, and to its use. | 02-10-2011 |
| 20110123480 | CHIMERIC PROTEINS AND USES THEREOF - The present invention provides a chimeric protein capable of killing or modifying a cell expressing abnormally high levels of a ligand of a receptor of the TNF/NGF family, comprising the amino acid sequence of at least one polypeptide consisting of an extracellular portion of said receptor connected to an effector molecule. In addition the invention provides pharmaceutical compositions comprising said chimeric protein and use thereof. | 05-26-2011 |
