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David Shealy

David Shealy, Downingtown, PA US

Patent application numberDescriptionPublished
20090074794Anti-TNF Antibodies, Compositions, Methods and Uses - The present invention relates to inhibiting TNF in patients having rheumatoid arthritis, psoriatic arthritis or ankylosing spondilitis, by administering anti-TNF antibodies comprising the heavy chain variable region of SEQ ID NO: 7 and the light chain variable region of SEQ ID NO:8, specific for at least one human tumor necrosis factor alpha (TNF) protein or fragment thereof.03-19-2009
20090081234ANTI-TNF ANTIBODIES, COMPOSITIONS, METHODS AND USES FOR TREATMENT OF DEPRESSION AND RELATED CONDITIONS - The present invention relates to novel anti-TNF antibodies for use in the treatment of depression, including therapeutic compositions, methods and devices.03-26-2009
20090081241Anti-TNF Antibodies, Compositions, Methods and Uses - The present invention relates to anti-TNF antibodies comprising all of the heavy chain variable CDR regions of SEQ ID NOS:1, 2 and 3 and/or all of the light chain variable CDR regions of SEQ ID NOS:4, 5 and 6, specific for at least one human tumor necrosis factor alpha (TNF) protein or fragment thereof, as well as nucleic acids encoding such anti-TNF antibodies, complementary nucleic acids, vectors, host cells, production methods and therapeutic methods.03-26-2009
20090202549Anti-IL-12 Antibodies, Epitopes, Compositions, Methods and Uses - An anti-IL-12 antibody that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of residues 15, 17-21, 23, 40-43, 45-47, 54-56 and 58-62 of the amino acid sequence of the p40 subunit of IL-12, including isolated nucleic acids that encode at least one anti-IL-12 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.08-13-2009
20090252743Anti-TNF Antibodies, Compositions, Methods and Uses - The present invention relates to anti-TNF antibodies comprising all of the heavy chain variable CDR regions of SEQ ID NOS: 1, 2 and 3 and/or all of the light chain variable CDR regions of SEQ ID NOS:4, 5 and 6, specific for at least one human tumor necrosis factor alpha (TNF) protein or fragment thereof, as well as nucleic acids encoding such anti-TNF antibodies, complementary nucleic acids, vectors, host cells, production methods and therapeutic methods.10-08-2009
20090274707Anti-IL-12 Antibodies, Nucleic Acids Encoding Antibodies, and Methods of Production - Isolated anti-IL-12 antibodies, nucleic acids encoding antibodies or antibody portions, vectors, host cells, and methods of making are useful for production of antibody or portions for treating and/or diagnosing IL-12 related conditions, diseases, and disorders.11-05-2009
20110082190Nucleic Acids Encoding Anti-IL-12 Antibody - Isolated anti-IL-12 antibodies, nucleic acids encoding antibodies or antibody portions, vectors, host cells, and methods of making are useful for production of antibody or portions for treating and/or diagnosing IL-12 related conditions, diseases, and disorders.04-07-2011

Patent applications by David Shealy, Downingtown, PA US

David Shealy, Radnor, PA US

Patent application numberDescriptionPublished
20090181027Anti-IL-12/23p40 Antibodies, Epitopes, Formulations, Compositions, Methods and Uses - An anti-IL-12/23p40 antibody that binds to a portion of the IL-12 or IL-23 protein corresponding to the p40 subunit of IL-12 or IL-23, including compositions, formulations, and methods of administration have applications in diagnostic and/or therapeutic uses and devices.07-16-2009