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David Liu

David Liu, Princeton, NJ US

Patent application numberDescriptionPublished
20100254582System and Method for Detecting Landmarks in a Three-Dimensional Image Volume - A method and apparatus for detecting vascular landmarks in a 3D image volume, such as a CT volume, is disclosed. One or more guide slices are detected in a 3D image volume. A set of landmark candidates for multiple target vascular landmarks are then detected based on the guide slices. A node potential value for each landmark candidate is generated based on an error value determined using spatial histogram-based error regression, and edge potential values for pairs of landmark candidates are generated based on a bifurcation analysis of the image volume using vessel tracing. The optimal landmark candidate for each target landmark is then determined using a Markov random field model based on the node potential values and the edge potential values.10-07-2010
20110002520Method and System for Automatic Contrast Phase Classification - A method and system for classifying a contrast phase of a 3D medical image, such as a computed tomography (CT) image or a magnetic resonance (MR) image, is disclosed. A plurality of anatomic landmarks are detected in a 3D medical image. A local volume of interest is estimated at each of the plurality of anatomic landmarks, and features are extracted from each local volume of interest. The contrast phase of the 3D volume is determined based on the extracted features using a trained classifier.01-06-2011
20110096964Method and System for Automatic Extraction of Personalized Left Atrium Models - A method and system for automatic extraction of personalized left atrium models is disclosed. A left atrium chamber body is segmented from a 3D image volume. At least one pulmonary venous ostium is detected on the segmented left atrium chamber body. At least one pulmonary vein trunk connected to the left atrium chamber body is segmented based on the detected pulmonary venous ostia.04-28-2011
20110222751Method and System for Automatic Detection and Segmentation of Axillary Lymph Nodes - A method and system for automatically detecting and segmenting lymph nodes in a 3D medical image, such as a CT image, is disclosed. A plurality of lymph node center point candidates are detected in the 3D medical image. A lymph node candidate is segmented for each of the detected lymph node center point candidates. Lymph nodes are detected from the segmented lymph node candidates by verifying the segmented lymph node candidates using a trained lymph node classifier.09-15-2011

David Liu, Los Altos, CA US

Patent application numberDescriptionPublished
20100261230SYSTEM COMPRISING DUAL-SIDED THERMAL CYCLER AND EMULSION PCR IN POUCH - A system and method are provided for large volume sample amplification adaptable for use with conventional PCR-based reactions as well as emulsion-based PCR reactions. A sample is retained in a pouch or flexible bag which permits bulk PCR amplification with efficient heat-transfer properties. For applications involving emulsion-based PCR amplification, the system and method provide improved uniformity in emulsion amplification and can be used to amplify large or small volume emulsions rapidly and reproducibly.10-14-2010
20110052446FLOW CELLS AND METHODS OF FILLING AND USING SAME - Various flowcell configurations and systems are provided as are methods of making and using same. The flowcells, systems, and methods of use can be useful in carrying out sequencing reactions and next generation sequencing methods.03-03-2011

Patent applications by David Liu, Los Altos, CA US

David Liu, Plainsboro, NJ US

Patent application numberDescriptionPublished
20100080434Method and System for Hierarchical Parsing and Semantic Navigation of Full Body Computed Tomography Data - A method and apparatus for hierarchical parsing and semantic navigation of a full or partial body computed tomography CT scan is disclosed. In particular, organs are segmented and anatomic landmarks are detected in a full or partial body CT volume. One or more predetermined slices of the CT volume are detected. A plurality of anatomic landmarks and organ centers are then detected in the CT volume using a discriminative anatomical network, each detected in a portion of the CT volume constrained by at least one of the detected slices. A plurality of organs, such as heart, liver, kidneys, spleen, bladder, and prostate, are detected in a sense of a bounding box and segmented in the CT volume, detection of each organ bounding box constrained by the detected organ centers and anatomic landmarks. Organ segmentation is via a database-guided segmentation method.04-01-2010

David Liu, Redmond, WA US

Patent application numberDescriptionPublished
20090316986FEATURE SELECTION AND EXTRACTION - Image feature selection and extraction (e.g., for image classifier training) is accomplished in an integrated manner, such that higher-order features are merely developed from first-order features selected for image classification. That is, first-order image features are selected for image classification from an image feature pool, initially populated with pre-extracted first-order image features. The selected first-order classifying features are paired with previously selected first-order classifying features to generate higher-order features. The higher-order features are placed into the image feature pool as they are developed or “on-the-fly” (e.g., for use in image classifier training).12-24-2009

David Liu, San Francisco, CA US

Patent application numberDescriptionPublished
20090277974Lawn And Garden Sprinkler Housing - A housing structure useful for protecting and stabilizing internal elements, such as a lawn and garden sprinkler. A housing has a hollow cylindrical interior with an open top and bottom. A resilient member is fixed inside the housing, and a central opening in the resilient member accommodates the body of the sprinkler. An adaptor may be used within the resilient member to accommodate different sprinkler sizes. A cover plate fits in the top opening of the housing and includes a central opening that allows the sprinkler head to extend through the opening. The resilient member resists any lateral forces imparted against the sprinkler head. A notch may be formed in the housing to accommodate a water pipe that is coupled to the sprinkler.11-12-2009

David Liu, Fremont, CA US

Patent application numberDescriptionPublished
20090170716ELECTRONIC SENSING FOR NUCLEIC ACID SEQUENCING - Methods for sequencing nucleic acids are presented. Sequencing is accomplished through the detection of a redox active species that is indicative of nucleotide incorporation. In embodiments of the invention, an electrochemical signal indicative of nucleotide incorporation is amplified through cycling before it is detected. Arrays are provided that are capable of massively parallel nucleic acid sequence determination.07-02-2009

David Liu, Chevy Chase, MD US

Patent application numberDescriptionPublished
20080209343CONTENT RECOMMENDATION USING THIRD PARTY PROFILES - A method for personalizing content for a particular user in a computing system comprising a user interface configured to display content. The method comprises identifying one or more features of a short term profile of a user that are not included in a long term profile of the user, using the one or more features to identify one or more third party profiles having features that substantially match the one or more features of the user's short term profile, accessing the identified one or more third party profiles, and providing one or more content items included in the third party profile to the user, the one or more content items having associated features that match the one or more features of the short term profile. An alternative method comprises accessing one or more third party profiles that are not a profile of the user, and using the accessed third party profile to identify a plurality of content items for recommendation to the user based on a feature set of the third party profile.08-28-2008
20080209351USER PROFILE SNAPSHOTS - A method for personalizing content for a particular user using profile snapshots in a computing system comprising a user interface configured to display content. The method comprises identifying a first snapshot of a user profile at a first point in time, identifying a second snapshot of a user profile at a second point in time occurring after the first point in time, maintaining a history of the first snapshot and the second snapshot, and allowing a user to access the history of the first snapshot and the second snapshot.08-28-2008

David Liu, Point Roberts, WA US

Patent application numberDescriptionPublished
20110212179MICRO-SPHERICAL POROUS BIOCOMPATIBLE SCAFFOLDS AND METHODS AND APPARATUS FOR FABRICATING SAME - Provided herein are bimodal porous polymer microspheres comprising macropores and micropores. Also provided herein are methods and apparatus for fabrication such microspheres. Further provided herein are methods of using bimodal porous polymer microspheres.09-01-2011

David Liu, Marietta, GA US

Patent application numberDescriptionPublished
20120017528FLOOR AND TILE SYSTEM WITH PAD - A method for installing flooring boards is provided. The method comprises laying down a two layer pad on a floor, applying a band of adhesive, laying a flooring board on the top of the two shifted-layer pad and the edge of the floor board occupying one half of the width of the band, and laying an adjacent floor board, which covers the remaining of the band of the adhesive.01-26-2012