Patent application number | Description | Published |
20100254582 | System and Method for Detecting Landmarks in a Three-Dimensional Image Volume - A method and apparatus for detecting vascular landmarks in a 3D image volume, such as a CT volume, is disclosed. One or more guide slices are detected in a 3D image volume. A set of landmark candidates for multiple target vascular landmarks are then detected based on the guide slices. A node potential value for each landmark candidate is generated based on an error value determined using spatial histogram-based error regression, and edge potential values for pairs of landmark candidates are generated based on a bifurcation analysis of the image volume using vessel tracing. The optimal landmark candidate for each target landmark is then determined using a Markov random field model based on the node potential values and the edge potential values. | 10-07-2010 |
20110002520 | Method and System for Automatic Contrast Phase Classification - A method and system for classifying a contrast phase of a 3D medical image, such as a computed tomography (CT) image or a magnetic resonance (MR) image, is disclosed. A plurality of anatomic landmarks are detected in a 3D medical image. A local volume of interest is estimated at each of the plurality of anatomic landmarks, and features are extracted from each local volume of interest. The contrast phase of the 3D volume is determined based on the extracted features using a trained classifier. | 01-06-2011 |
20110096964 | Method and System for Automatic Extraction of Personalized Left Atrium Models - A method and system for automatic extraction of personalized left atrium models is disclosed. A left atrium chamber body is segmented from a 3D image volume. At least one pulmonary venous ostium is detected on the segmented left atrium chamber body. At least one pulmonary vein trunk connected to the left atrium chamber body is segmented based on the detected pulmonary venous ostia. | 04-28-2011 |
20110222751 | Method and System for Automatic Detection and Segmentation of Axillary Lymph Nodes - A method and system for automatically detecting and segmenting lymph nodes in a 3D medical image, such as a CT image, is disclosed. A plurality of lymph node center point candidates are detected in the 3D medical image. A lymph node candidate is segmented for each of the detected lymph node center point candidates. Lymph nodes are detected from the segmented lymph node candidates by verifying the segmented lymph node candidates using a trained lymph node classifier. | 09-15-2011 |
20120070053 | Method and System for Vascular Landmark Detection - The present invention provides a method and system for vascular landmark detection in CT volumes. A CT volume is received and an initial position of a plurality of vascular landmarks is detected. The initial position of each of the plurality of vascular landmarks is then adjusted in order to position each vascular landmark inside a vessel lumen. A new position of each of the plurality of vascular landmarks representing the adjusted initial positions is output. | 03-22-2012 |
20120070055 | Method and System for Liver Lesion Detection - A method and system for automatically detecting liver lesions in medical image data, such as 3D CT images, is disclosed. A liver region is segmented in a 3D image. Liver lesion center candidates are detected in the segmented liver region. Lesion candidates are segmented corresponding to the liver lesion center candidates, and lesions are detected from the segmented lesion candidates using learning based verification. | 03-22-2012 |
20120070074 | Method and System for Training a Landmark Detector using Multiple Instance Learning - An apparatus and method for training a landmark detector receives training data which includes a plurality of positive training bags, each including a plurality of positively annotated instances, and a plurality of negative training bags, each including at least one negatively annotated instance. Classification function is initialized by training a first weak classifier based on the positive training bags and the negative training bags. All training instances are evaluated using the classification function. For each of a plurality of remaining classifiers, a cost value gradient is calculated based on spatial context information of each instance in each positive bag evaluated by the classification function. A gradient value associated with each of the remaining weak classifiers is calculated based on the cost value gradients, and a weak classifier is selected which has a lowest associated gradient value and given a weighting parameter and added to the classification function. | 03-22-2012 |
20120106810 | Automated Rib Ordering and Pairing - Ribs are automatically ordered and paired. After ordering ribs on each side, magnetic and spring functions are used to solve for rib pairing. The magnetic function is used to constrain possible pairs across sides, and the spring function is used to maintain the order on each side while accounting for missing or fused ribs. | 05-03-2012 |
20120183193 | Method and System for Automatic Detection of Spinal Bone Lesions in 3D Medical Image Data - A method and system for automatic detection and volumetric quantification of bone lesions in 3D medical images, such as 3D computed tomography (CT) volumes, is disclosed. Regions of interest corresponding to bone regions are detected in a 3D medical image. Bone lesions are detected in the regions of interest using a cascade of trained detectors. The cascade of trained detectors automatically detects lesion centers and then estimates lesion size in all three spatial axes. A hierarchical multi-scale approach is used to detect bone lesions using a cascade of detectors on multiple levels of a resolution pyramid of the 3D medical image. | 07-19-2012 |
20120203530 | Method and System for Patient-Specific Computational Modeling and Simulation for Coupled Hemodynamic Analysis of Cerebral Vessels - A method and system for patient-specific computational modeling and simulation for coupled hemodynamic analysis of cerebral vessels is disclosed. An anatomical model of a cerebral vessel is extracted from 3D medical image data. The anatomical model of the cerebral vessel includes an inner wall and an outer wall of the cerebral vessel. Blood flow in the cerebral vessel and deformation of the cerebral vessel wall are simulated using coupled computational fluid dynamics (CFD) and computational solid mechanics (CSM) simulations based on the anatomical model of the cerebral vessel. | 08-09-2012 |
20130072782 | SYSTEM AND METHOD FOR AUTOMATIC MAGNETIC RESONANCE VOLUME COMPOSITION AND NORMALIZATION - A method and system for automatic magnetic resonance (MR) volume composition and normalization is disclosed. In one embodiment, a plurality of MR volumes is received. A composite MR volume is generated from the plurality of MR volumes. Volume normalization of the composite MR volume is then performed to correct intensity inhomogeneity in the composite MR volume. The volume normalization of the composite MR volume may be performed using template MR volume or without a template MR volume. | 03-21-2013 |
Patent application number | Description | Published |
20090277974 | Lawn And Garden Sprinkler Housing - A housing structure useful for protecting and stabilizing internal elements, such as a lawn and garden sprinkler. A housing has a hollow cylindrical interior with an open top and bottom. A resilient member is fixed inside the housing, and a central opening in the resilient member accommodates the body of the sprinkler. An adaptor may be used within the resilient member to accommodate different sprinkler sizes. A cover plate fits in the top opening of the housing and includes a central opening that allows the sprinkler head to extend through the opening. The resilient member resists any lateral forces imparted against the sprinkler head. A notch may be formed in the housing to accommodate a water pipe that is coupled to the sprinkler. | 11-12-2009 |
20140363455 | DLL3 MODULATORS AND METHODS OF USE - Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided. | 12-11-2014 |
20140363826 | DLL3 MODULATORS AND METHODS OF USE - Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided. | 12-11-2014 |
20140363887 | DLL3 MODULATORS AND METHODS OF USE - Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided. | 12-11-2014 |
20140364590 | DLL3 MODULATORS AND METHODS OF USE - Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided. | 12-11-2014 |
20140364593 | DLL3 MODULATORS AND METHODS OF USE - Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided. | 12-11-2014 |
20140370037 | DLL3 MODULATORS AND METHODS OF USE - Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided. | 12-18-2014 |
20150018531 | ANTI SEZ6 ANTIBODIES AND METHODS OF USE - Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided. | 01-15-2015 |
20150265724 | ANTI-DLL3 ANTIBODY DRUG CONJUGATES AND METHODS OF USE - Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat tumors having neuroendocrine features are provided. | 09-24-2015 |
20150328332 | ANTI-DLL3 ANTIBODY DRUG CONJUGATES - Pharmaceutical compositions to treat proliferative disorders are provided. | 11-19-2015 |
20150337048 | ANTI-CD324 MONOCLONAL ANTIBODIES AND USES THEREOF - Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided. | 11-26-2015 |
20150368352 | NOVEL MULTISPECIFIC CONSTRUCTS - Provided are novel multispecific antibody constructs and multispecific antibody drug conjugates (ADCs), and methods of using such antibodies and ADCs to treat cancer. IgG-like bispecific antibodies have different binding specificities on each arm of the antibody. They are similar in structure to monospecific IgGs in that they contain two heavy chains with VH, CH1, CH2 and CH3 regions, and two light chains with VL and CL regions. | 12-24-2015 |
Patent application number | Description | Published |
20090170716 | ELECTRONIC SENSING FOR NUCLEIC ACID SEQUENCING - Methods for sequencing nucleic acids are presented. Sequencing is accomplished through the detection of a redox active species that is indicative of nucleotide incorporation. In embodiments of the invention, an electrochemical signal indicative of nucleotide incorporation is amplified through cycling before it is detected. Arrays are provided that are capable of massively parallel nucleic acid sequence determination. | 07-02-2009 |
20120296706 | Automatic Valid Vote Count Storage using Secure Embedded Non Volatile Memory - A non-volatile memory system adapted for securely registering votes within a voting system is described. The votes are encoded as a set of logically grouped cells based on a voter's selection of an item. The encoding assures that the votes are easily distinguishable by a read circuit. | 11-22-2012 |
20140065772 | METHOD OF MAKING INTEGRATED CIRCUIT EMBEDDED WITH NON-VOLATILE PROGRAMMABLE MEMORY HAVING VARIABLE COUPLING - A programmable non-volatile device is made with a floating gate that functions as a FET gate that overlaps a portion of a source/drain region and allows for variable coupling through geometry and/or biasing conditions. This allows a programming voltage for the device to be imparted to the floating gate through variable capacitive coupling, thus changing the state of the device. Multi-state embodiments are also possible. The invention can be used in environments such as data encryption, reference trimming, manufacturing ID, security ID, and many other applications. | 03-06-2014 |
20150287258 | Automatic Valid Vote Count Storage using Secure Embedded Non Volatile Memory - A non-volatile memory system adapted for securely registering votes within a voting system is described. The votes are encoded as a set of logically grouped cells based on a voter's selection of an item. The encoding assures that the votes are easily distinguishable by a read circuit. | 10-08-2015 |
Patent application number | Description | Published |
20080209343 | CONTENT RECOMMENDATION USING THIRD PARTY PROFILES - A method for personalizing content for a particular user in a computing system comprising a user interface configured to display content. The method comprises identifying one or more features of a short term profile of a user that are not included in a long term profile of the user, using the one or more features to identify one or more third party profiles having features that substantially match the one or more features of the user's short term profile, accessing the identified one or more third party profiles, and providing one or more content items included in the third party profile to the user, the one or more content items having associated features that match the one or more features of the short term profile. An alternative method comprises accessing one or more third party profiles that are not a profile of the user, and using the accessed third party profile to identify a plurality of content items for recommendation to the user based on a feature set of the third party profile. | 08-28-2008 |
20080209351 | USER PROFILE SNAPSHOTS - A method for personalizing content for a particular user using profile snapshots in a computing system comprising a user interface configured to display content. The method comprises identifying a first snapshot of a user profile at a first point in time, identifying a second snapshot of a user profile at a second point in time occurring after the first point in time, maintaining a history of the first snapshot and the second snapshot, and allowing a user to access the history of the first snapshot and the second snapshot. | 08-28-2008 |
20130066973 | CONTENT RECOMMENDATION USING THIRD PARTY PROFILES - A method includes identifying one or more features of a short term profile of a user that are not included in a long term profile of the user, using the one or more features to identify one or more third party profiles having features that substantially match the one or more features of the user's short term profile, accessing the identified one or more third party profiles, and providing one or more content items included in the third party profile to the user, the one or more content items having associated features that match the one or more features of the short term profile. An alternative method includes accessing one or more third party profiles that are not a profile of the user, and using the accessed third party profile to identify a plurality of content items for recommendation based on a feature set of the third party profile. | 03-14-2013 |
Patent application number | Description | Published |
20130273640 | NUCLEIC ACID SAMPLE PREPARATION - The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples. | 10-17-2013 |
20140127697 | NUCLEIC ACID SAMPLE PREPARATION - The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples. | 05-08-2014 |
20140183042 | NUCLEIC ACID SAMPLE PREPARATION - The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples. | 07-03-2014 |
20140183043 | NUCLEIC ACID SAMPLE PREPARATION - The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples. | 07-03-2014 |
20140238860 | NUCLEIC ACID SAMPLE PREPARATION - The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples. | 08-28-2014 |
20140248627 | NUCLEIC ACID SAMPLE PREPARATION - The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples. | 09-04-2014 |
20140356877 | NUCLEIC ACID SAMPLE PREPARATION - The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples. | 12-04-2014 |
20150083595 | NUCLEIC ACID SAMPLE PREPARATION - The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples. | 03-26-2015 |
20150104858 | NUCLEIC ACID SAMPLE PREPARATION - The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples. | 04-16-2015 |
Patent application number | Description | Published |
20150051484 | Histological Differentiation Grade Prediction of Hepatocellular Carcinoma in Computed Tomography Images - A method of determining the histological grade of Hepatocellular Carcinoma (HCC) including: acquiring a Computed Tomography (CT) image of a person including an HCC tumor; delineating the HCC tumor; and assigning a histological grade to the HCC tumor, wherein assigning the histological grade to the HCC tumor includes: applying a plurality of filters to the HCC tumor, wherein each of the filters produces a corresponding response image and, for each of the filters, a convolution operation is performed on the filter and the CT image to produce the response image corresponding to that filter; computing an average response of the HCC tumor in each of the response images and recording each of the average responses as an Independent Subspace Analysis (ISA) feature; and determining the histological grade of the HCC tumor based on the ISA features by using a classifier. | 02-19-2015 |
20150087957 | EARLY THERAPY RESPONSE ASSESSMENT OF LESIONS - For therapy response assessment, texture features are input for machine learning a classifier and for using a machine learnt classifier. Rather than or in addition to using formula-based texture features, data driven texture features are derived from training images. Such data driven texture features are independent analysis features, such as features from independent subspace analysis. The texture features may be used to predict the outcome of therapy based on a few number of or even one scan of the patient. | 03-26-2015 |
20150238148 | METHOD AND SYSTEM FOR ANATOMICAL OBJECT DETECTION USING MARGINAL SPACE DEEP NEURAL NETWORKS - A method and system for anatomical object detection using marginal space deep neural networks is disclosed. The pose parameter space for an anatomical object is divided into a series of marginal search spaces with increasing dimensionality. A respective deep neural network is trained for each of the marginal search spaces, resulting in a series of trained deep neural networks. Each of the trained deep neural networks can evaluate hypotheses in a current parameter space using discriminative classification or a regression function. An anatomical object is detected in a medical image by sequentially applying the series of trained deep neural networks to the medical image. | 08-27-2015 |