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David L. Williams
David L. Williams, Telford, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100144858 | Treatment of movement disorders with a metabotropic glutamate 4 receptor positive allosteric modulator - An mGluR4 receptor positive allosteric modulator is useful, alone or in combination with a neuroleptic agent, for treating or preventing movement disorders such as Parkinson's disease, dyskinesia, tardive dyskinesia, drug-induced parkinsonism, postencephalitic parkinsonism, progressive supranuclear palsy, multiple system atrophy, corticobasal degeneration, parkinsonian-ALS dementia complex, basal ganglia calcification, akinesia, akinetic-rigid syndrome, bradykinesia, dystonia, medication-induced parkinsonian, Gilles de la Tourette syndrome, Huntington's disease, tremor, chorea, myoclonus, tick disorder, and dystonia. | 06-10-2010 |
| 20110081297 | Novel Substituted Pyrazoles, 1,2,4-Oxadiazoles, and 1,3,4-Oxadiazoles - The present invention relates to novel amyloid binding compounds and methods for measuring effects of the compounds, by measuring changes of amyloid plaque level in living patients. More specifically, the present invention relates to a method of using the compounds of this invention as tracers in positron emission tomography (PET) imaging to study amyloid deposits in brain in vivo to allow diagnosis of Alzheimer's disease. Thus, the present invention relates to use of the novel amyloid binding compounds as a diagnostic. The invention further relates to a method of measuring clinical efficacy of Alzheimer's disease therapeutic agents. Specifically, the present invention relates to novel aryl or heteroaryl substituted pyrazole derivatives, compositions, and therapeutic uses and processes for making such compounds. | 04-07-2011 |
| 20110085985 | NOVEL SUBSTITUTED AZABENZOXAZOLES - The present invention relates to novel amyloid binding compounds of formula (I) and methods for measuring effects of the compounds, by measuring changes of amyloid plaque level in living patients. More specifically, the present invention relates to a method of using the compounds of this invention as tracers in positron emission tomography (PET/) imaging to study amyloid deposits in brain in vivo to allow diagnosis of Alzheimer's disease. Thus, the present invention relates to use of the novel amyloid binding compounds as a diagnostic. The invention further relates to a method of measuring clinical efficacy of Alzheimer's disease therapeutic agents. Specifically, the present invention relates to novel aryl or heteroaryl substituted azabenzoxazole derivatives, compositions, and therapeutic uses and processes for making such compounds, or a pharmaceutically acceptable salt, solvate or in vivo hydrolysable ester thereof, wherein: X is O or S; A and Y independently are N, or CH; | 04-14-2011 |
| 20110212031 | NOVEL SUBSTITUTED AZABENZOXAZOLES - The present invention relates to novel MAO-B binding compounds and methods for measuring effects of the compounds, by measuring changes of MAO-B levels in living patients. More specifically, the present invention relates to use of the compounds of this invention as therapeutic agents for inhibition of MAO-B activity as well as a method of using the compounds of this invention as tracers in positron emission tomography (PET) imaging to study MAO-B levels in brain in vivo to allow diagnosis of Alzheimer's disease. Thus, the present invention relates to use of the novel MAO-B binding compounds as diagnostic, as we a therapeutic, agents. The invention further relates to a method of measuring clinical efficacy of Alzheimer's disease therapeutic agents. Specifically, the present invention relates to novel aryl or heteroaryl substituted azabenzoxazole derivatives, compositions, and therapeutic uses and processes for making such compounds. | 09-01-2011 |
David L. Williams, Colleyville, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100102194 | Variable Stiffness Support - A variable stiffness support is disclosed. The variable stiffness support has a support housing that is configured to adjust the orientation of an internal elastomer assembly. The support housing includes an adjustment mechanism, and the elastomer assembly includes an outer ring that encircles an elastomeric material, a central bushing embedded in the elastomeric material, and a plurality of shims embedded in the elastomeric material in a parallel planar fashion. | 04-29-2010 |
David L. Williams, Belmont, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090041230 | Mobile Client Device Driven Data Backup - Tasks associated with backing up the data of a mobile client device are performed predominantly by the mobile client device. A backup server functions as a server with limited functionality that merely stores backup data received from the mobile client device and retrieves the backup data under the request of the mobile client device. The mobile client device functions as a master device, and the backup server functions as a slave device. A backup program for performing tasks associated with the backup operation on the mobile client device may itself be stored as part of the backup data. | 02-12-2009 |
| 20100048231 | Handheld Threading - The present invention determines which messages to display in message threads to a user. An electronic communication device receives and stores numerous SMS messages transported through an SMS network, but the SMS messages are sent without explicit linking information such as a previous message or subject line. A threading module applies threading rules to determine which messages to correlate into an SMS message thread through implicit link information. The threading rules thread outgoing messages sent in response to an incoming message from a user, or incoming messages where a previous outgoing message was sent to the user. An SMS application displays threads in a user interface and indicates messages threads with an icon in one view, and displays an expanded message thread in another view. | 02-25-2010 |
David L. Williams, Normal, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20090149515 | Treatments for the control of schistosomiasis - A method for controlling schistosome parasites in a mammal comprising delivering an effective amount of an agent for silencing TGR activity in the parasites. | 06-11-2009 |
David L. Williams, Prescott, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20090011192 | Method, system, and apparatus for producing dimensional image articles utilizing a cushioning assembly - Methods, apparatus, and system for a protecting an optical lens material during formation of a dimensional image article. A heat compression laminator including a cushioning assembly provides an insulating barrier between the lower compression assembly of the heat compression laminator and the individual lenses of an optical lens material, such as the lenticules on a lenticular lens material. The cushioning web protects the optical lens material so as to prevent significant deformation during the application of heat and pressure in a laminating step. Use of the cushioning web can be especially advantageous during formation of clear, transparent, or semi-transparent dimensional image articles. | 01-08-2009 |
| 20110132783 | DURABLE PACKAGING ASSEMBLY FOR ARTICLES - A carrier assembly for transaction cards or other articles. The assembly includes a carrier having a front panel and a rear panel, and a transaction card or other article retained within the carrier. At least one panel of the carrier comprises a lens sheet assembly including a lens sheet, and an optional image layer. The carrier with lens sheet assembly provides enhanced security features, increased durability, and eye-catching features compared to traditional carrier or packaging assemblies. | 06-09-2011 |
David L. Williams, Oak Park, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20110207784 | OXADIAZOLE-2-OXIDES AS ANTISCHISTOSOMAL AGENTS - The invention provides 1,2,5-oxadiazole-containing compounds of Formula (I), wherein R | 08-25-2011 |
David L. Williams, Menlo Park, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110278464 | RADIATION DETECTOR AND FABRICATION PROCESS - A monolithic integrated radiation detector includes a photodetector and a scintillator deposited directly on the photodetector. Preferably the photodetector is silicon and the scintillator is a rare earth phosphor. The rare earth phosphor is crystal lattice matched to the silicon by a transitional layer epitaxially grown therebetween. | 11-17-2011 |