Inventors list

Assignees list

Classification tree browser

Top 100 Inventors

Top 100 Assignees

David L. Williams

David L. Williams, Telford, PA US

Patent application number	Description	Published
20100144858	Treatment of movement disorders with a metabotropic glutamate 4 receptor positive allosteric modulator - An mGluR4 receptor positive allosteric modulator is useful, alone or in combination with a neuroleptic agent, for treating or preventing movement disorders such as Parkinson's disease, dyskinesia, tardive dyskinesia, drug-induced parkinsonism, postencephalitic parkinsonism, progressive supranuclear palsy, multiple system atrophy, corticobasal degeneration, parkinsonian-ALS dementia complex, basal ganglia calcification, akinesia, akinetic-rigid syndrome, bradykinesia, dystonia, medication-induced parkinsonian, Gilles de la Tourette syndrome, Huntington's disease, tremor, chorea, myoclonus, tick disorder, and dystonia.	06-10-2010
20110081297	Novel Substituted Pyrazoles, 1,2,4-Oxadiazoles, and 1,3,4-Oxadiazoles - The present invention relates to novel amyloid binding compounds and methods for measuring effects of the compounds, by measuring changes of amyloid plaque level in living patients. More specifically, the present invention relates to a method of using the compounds of this invention as tracers in positron emission tomography (PET) imaging to study amyloid deposits in brain in vivo to allow diagnosis of Alzheimer's disease. Thus, the present invention relates to use of the novel amyloid binding compounds as a diagnostic. The invention further relates to a method of measuring clinical efficacy of Alzheimer's disease therapeutic agents. Specifically, the present invention relates to novel aryl or heteroaryl substituted pyrazole derivatives, compositions, and therapeutic uses and processes for making such compounds.	04-07-2011
20110085985	NOVEL SUBSTITUTED AZABENZOXAZOLES - The present invention relates to novel amyloid binding compounds of formula (I) and methods for measuring effects of the compounds, by measuring changes of amyloid plaque level in living patients. More specifically, the present invention relates to a method of using the compounds of this invention as tracers in positron emission tomography (PET/) imaging to study amyloid deposits in brain in vivo to allow diagnosis of Alzheimer's disease. Thus, the present invention relates to use of the novel amyloid binding compounds as a diagnostic. The invention further relates to a method of measuring clinical efficacy of Alzheimer's disease therapeutic agents. Specifically, the present invention relates to novel aryl or heteroaryl substituted azabenzoxazole derivatives, compositions, and therapeutic uses and processes for making such compounds, or a pharmaceutically acceptable salt, solvate or in vivo hydrolysable ester thereof, wherein: X is O or S; A and Y independently are N, or CH;	04-14-2011
20110212031	NOVEL SUBSTITUTED AZABENZOXAZOLES - The present invention relates to novel MAO-B binding compounds and methods for measuring effects of the compounds, by measuring changes of MAO-B levels in living patients. More specifically, the present invention relates to use of the compounds of this invention as therapeutic agents for inhibition of MAO-B activity as well as a method of using the compounds of this invention as tracers in positron emission tomography (PET) imaging to study MAO-B levels in brain in vivo to allow diagnosis of Alzheimer's disease. Thus, the present invention relates to use of the novel MAO-B binding compounds as diagnostic, as we a therapeutic, agents. The invention further relates to a method of measuring clinical efficacy of Alzheimer's disease therapeutic agents. Specifically, the present invention relates to novel aryl or heteroaryl substituted azabenzoxazole derivatives, compositions, and therapeutic uses and processes for making such compounds.	09-01-2011

David L. Williams, Colleyville, TX US

Patent application number	Description	Published
20100102194	Variable Stiffness Support - A variable stiffness support is disclosed. The variable stiffness support has a support housing that is configured to adjust the orientation of an internal elastomer assembly. The support housing includes an adjustment mechanism, and the elastomer assembly includes an outer ring that encircles an elastomeric material, a central bushing embedded in the elastomeric material, and a plurality of shims embedded in the elastomeric material in a parallel planar fashion.	04-29-2010

David L. Williams, Belmont, CA US

Patent application number	Description	Published
20090041230	Mobile Client Device Driven Data Backup - Tasks associated with backing up the data of a mobile client device are performed predominantly by the mobile client device. A backup server functions as a server with limited functionality that merely stores backup data received from the mobile client device and retrieves the backup data under the request of the mobile client device. The mobile client device functions as a master device, and the backup server functions as a slave device. A backup program for performing tasks associated with the backup operation on the mobile client device may itself be stored as part of the backup data.	02-12-2009
20100048231	Handheld Threading - The present invention determines which messages to display in message threads to a user. An electronic communication device receives and stores numerous SMS messages transported through an SMS network, but the SMS messages are sent without explicit linking information such as a previous message or subject line. A threading module applies threading rules to determine which messages to correlate into an SMS message thread through implicit link information. The threading rules thread outgoing messages sent in response to an incoming message from a user, or incoming messages where a previous outgoing message was sent to the user. An SMS application displays threads in a user interface and indicates messages threads with an icon in one view, and displays an expanded message thread in another view.	02-25-2010

David L. Williams, Normal, IL US

Patent application number	Description	Published
20090149515	Treatments for the control of schistosomiasis - A method for controlling schistosome parasites in a mammal comprising delivering an effective amount of an agent for silencing TGR activity in the parasites.	06-11-2009

David L. Williams, Prescott, WI US

Patent application number	Description	Published
20090011192	Method, system, and apparatus for producing dimensional image articles utilizing a cushioning assembly - Methods, apparatus, and system for a protecting an optical lens material during formation of a dimensional image article. A heat compression laminator including a cushioning assembly provides an insulating barrier between the lower compression assembly of the heat compression laminator and the individual lenses of an optical lens material, such as the lenticules on a lenticular lens material. The cushioning web protects the optical lens material so as to prevent significant deformation during the application of heat and pressure in a laminating step. Use of the cushioning web can be especially advantageous during formation of clear, transparent, or semi-transparent dimensional image articles.	01-08-2009
20110132783	DURABLE PACKAGING ASSEMBLY FOR ARTICLES - A carrier assembly for transaction cards or other articles. The assembly includes a carrier having a front panel and a rear panel, and a transaction card or other article retained within the carrier. At least one panel of the carrier comprises a lens sheet assembly including a lens sheet, and an optional image layer. The carrier with lens sheet assembly provides enhanced security features, increased durability, and eye-catching features compared to traditional carrier or packaging assemblies.	06-09-2011

David L. Williams, Oak Park, IL US

Patent application number	Description	Published
20110207784	OXADIAZOLE-2-OXIDES AS ANTISCHISTOSOMAL AGENTS - The invention provides 1,2,5-oxadiazole-containing compounds of Formula (I), wherein R	08-25-2011

David L. Williams, Menlo Park, CA US

Patent application number	Description	Published
20110278464	RADIATION DETECTOR AND FABRICATION PROCESS - A monolithic integrated radiation detector includes a photodetector and a scintillator deposited directly on the photodetector. Preferably the photodetector is silicon and the scintillator is a rare earth phosphor. The rare earth phosphor is crystal lattice matched to the silicon by a transitional layer epitaxially grown therebetween.	11-17-2011
20120019902	INTERGRATED PUMP LASER AND RARE EARTH WAVEGUIDE AMPLIFIER - A light amplifier includes a single crystal semiconductor substrate with a rare earth oxide, light amplifying gain medium deposited on the substrate and formed into a light waveguide, and a pump laser. A lattice matching virtual substrate integrates the pump laser to the gain medium with a first opposed surface crystal lattice matched to the gain medium and second opposed surface crystal lattice matched to the pump laser. The pump laser is positioned with a light output surface coupled to a light input surface of the gain medium so as to introduce pump energy into the light waveguide. The light amplifier has a very small footprint and allows the integration of control and monitoring electronics.	01-26-2012
20120145243	SOLAR CELLS WITH MAGNETICALLY ENHANCED UP-CONVERSION - A method of magnetically enhancing up-conversion components includes providing at least one of up-conversion material and sensitizer material (i.e. up-conversion components), generally in conjunction with a semiconductor solar cell, and positioning magnetic apparatus adjacent the up-conversion components to supply a magnetic field to the up-conversion components. The magnetic field has an intensity and direction selected to enhance operation of the up-conversion components.	06-14-2012
20120147906	LASER COOLING OF MODIFIED SOI WAFER - A laser cooling system includes a substrate, an REO layer of single crystal rare earth oxide including at least one rare earth element positioned on the surface of the substrate, and an active layer of single crystal semiconductor material positioned on the REO layer to form a semiconductor-on-insulator (SOI) device. Light guiding structure is at least partially formed by the REO layer so as to introduce energy elements into the REO layer and produce cooling by anti-Stokes fluorescence. The active layer of single crystal semiconductor material is positioned on the REO layer in proximity to the light guiding structure so as to receive the cooling.	06-14-2012

David L. Williams, San Diego, CA US

Patent application number	Description	Published
20120198603	ELECTRONIC HELMET - An electronic helmet is provided that includes a helmet body and an integrated electronic system disposed in the helmet body, providing a number of convenient functions. The helmet body has a hard outer shell and a hard inner shell mounted to the outer shell such that a cavity is defined between the outer and the inner shells. The inner shell can include suitable material to provide the wearer effective RF shielding from the electronic system, such as, nickel-plated carbon fiber to provide RF shielding. The helmet body further includes a shock-absorbent structure disposed between the inner shell and the head of a wearer.	08-09-2012