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David Knight

David Knight, Radnor, PA US

Patent application numberDescriptionPublished
20090181027Anti-IL-12/23p40 Antibodies, Epitopes, Formulations, Compositions, Methods and Uses - An anti-IL-12/23p40 antibody that binds to a portion of the IL-12 or IL-23 protein corresponding to the p40 subunit of IL-12 or IL-23, including compositions, formulations, and methods of administration have applications in diagnostic and/or therapeutic uses and devices.07-16-2009
20110076264IMMUNOGLOBULIN CLEAVAGE FRAGMENTS AS DISEASE INDICATORS AND COMPOSITIONS FOR DETECTING AND BINDING SUCH - The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG protease cleavage products to restore effector function to antibody compositions that are subject to protease cleavage.03-31-2011

David Knight, Belmont, CA US

Patent application numberDescriptionPublished
20110023096TOKEN-BASED CONTROL OF PERMITTED SUB-SESSIONS FOR ONLINE COLLABORATIVE COMPUTING SESSIONS - In one embodiment, a client device may send one or more sub-session requests to one or more corresponding session controllers through a computer network to obtain one or more corresponding sub-session tokens that indicate in which sub-sessions of an online collaborative computing session the client device is permitted to participate. The client device may then receive particular sub-session tokens (e.g., based on certain permissions), which may then be sent to a collaboration server to establish one or more permitted sub-sessions of the online collaborative computing session with the client device as indicated by the received sub-session tokens.01-27-2011
20110196930METHODS AND APPARATUSES FOR REPORTING BASED ON ATTENTION OF A USER DURING A COLLABORATION SESSION - In one embodiment, a collaboration session is conducted between a plurality of participant devices. The content shared during the collaboration session is recorded. The recorded content indicates content that was shared at various times during the collaboration session. An activity status of at least some participant devices is recorded at various times during the collaboration session. The activity status of the at least some participant devices is correlated with the content that was being shared at each of a plurality of times during the collaboration session. For a selected time of the plurality of times during the collaboration session, the content that was being shared in the collaboration session at the selected time and an indication of the activity status of the at least some participant devices at the selected time is displayed.08-11-2011

Patent applications by David Knight, Belmont, CA US

David Knight, King Of Prussia, PA US

Patent application numberDescriptionPublished
20100179143NAPHTHYRIDINE, DERIVATIVES AS P13 KINASE INHIBITORS - Invented is a method of inhibiting the activity/function of PI3 kinases using naphthyridine derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of naphthyridine derivatives.07-15-2010

David Knight, Berwyn, PA US

Patent application numberDescriptionPublished
20080312172Anti-IL-6 Antibodies, Compositions, Methods and Uses - The present invention relates to at least one novel chimeric, humanized or CDR-grafted anti-IL-6 antibodies derived from the murine CLB-8 antibody, including isolated nucleic acids that encode at least one such anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.12-18-2008
20090022718Methods of treating a blood pathology using anti-TNF antibodies and fragments thereof - Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-α (TNFα) and are useful in vivo diagnosis and therapy of a number of TNFα-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.01-22-2009
20090202549Anti-IL-12 Antibodies, Epitopes, Compositions, Methods and Uses - An anti-IL-12 antibody that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of residues 15, 17-21, 23, 40-43, 45-47, 54-56 and 58-62 of the amino acid sequence of the p40 subunit of IL-12, including isolated nucleic acids that encode at least one anti-IL-12 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.08-13-2009
20090291084ANTI- IL-6 ANTIBODIES, COMPOSITIONS, METHODS AND USES - The present invention relates to at least one novel chimeric, humanized or CDR-grafted anti-IL-6 antibodies derived from the murine CLB-8 antibody, including isolated nucleic acids that encode at least one such anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.11-26-2009

Patent applications by David Knight, Berwyn, PA US

David Knight, San Francisco, CA US

Patent application numberDescriptionPublished
20090132280System and Method for a Worklist Search and Creation Tool in a Healthcare Environment - Certain embodiments of the present invention provide a system and method for a worklist search and creation tool in a healthcare environment. In an embodiment, the worklist search and creation system includes a worklist user interface, which includes an input search field adapted to receive inputted search data. The system also includes one or more databases for storing information that is associated with a data entry, which includes multiple fields of identification data. In addition, the system includes a search engine for searching the multiple fields of the data entry associated with the information stored in the one or more databases for identifying data that at least partially matches the inputted search data of the worklist user interface and displays any of the at least partially matching data entry in the worklist user interface.05-21-2009
20090132963METHOD AND APPARATUS FOR PACS SOFTWARE TOOL CUSTOMIZATION AND INTERACTION - Certain embodiments of the present invention provide methods and systems for circular tool menu configuration and use with a clinical application. Certain embodiments provide a user interface providing software tools and customization for a picture archiving and communication system. The user interface includes a pie-shaped menu including a plurality of tool segments arranged as pieces of the pie-shaped menu. The user interface also includes a pointer movable by a user to select one of the plurality of tool segments in the pie-shaped menu. The user interface further includes an image review area displayed underneath the pie-shaped menu. In certain embodiments, the user interface further includes a tool bar including one or more tools and functions associated with a tool segment in the pie-shaped menu, for example.05-21-2009

David Knight, Mountain View, CA US

Patent application numberDescriptionPublished
20090112155Micro Diaphragm Pump - The invention relates to micropumps for infusing fluids. More specifically, the present disclosure describes and illustrates a micropump design that may be useful for infusing insulin into a diabetic patient. The disclosed design employs a pump chamber that has a diaphragm and a plurality of check valves that are configured to avoid leakage from the reservoir through the pump engine and into an infusion device and, also, to ensure the complete, accurate evacuation of the pump chamber.04-30-2009

David Knight, Hampshire GB

Patent application numberDescriptionPublished
20110172394IMPLANTABLE MATERIAL FOR THE REPAIR, AUGMENTATION, OR REPLACEMENT OF BONE AND A METHOD FOR THE PREPARATION THEREOF - A method for the preparation of an implantable material for the repair, augmentation or replacement of bone from a fibroin solution, the method comprising the steps of: preparing a gel from the fibroin solution; preparing a material by subjecting the gel to one or more steps of freezing and thawing the gel, wherein the step of preparing the gel from the fibroin solution is performed in the presence of phosphate ions. The material may be treated with calcium ionstoform a fibroin-apatite. A further method comprises the step of treating the material with an isocyanate. The invention also extends to a method for the preparation of an implantable material, wherein a regenerated fibroin solution is used. Also, there is an implantable material and an implant.07-14-2011

David Knight, San Jose, CA US

Patent application numberDescriptionPublished
20110202599METHODS AND APPARATUSES FOR RECORDING AND VIEWING A COLLABORATION SESSION - In one embodiment, a collaboration session is maintained among a plurality of participant devices, at least one participant device operating as a presenter device that shares content during the collaboration session. Content shared during the collaboration session is recorded. A request is detected during the collaboration session from a particular participant device of the plurality of participant devices to view at least a portion of the recorded content. In response to the request during the collaboration from the particular participant device to view the at least a portion of the recorded content, the at least a portion of the recorded content is played back while the collaboration session is still ongoing, wherein the particular participant device remains an active participant in the ongoing collaboration session during playback of the at least a portion of the recorded content. Eventually, playback of the at least a portion of the recorded content is ceased.08-18-2011