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David King
David King, Shrewsbury, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110103578 | SYSTEMS AND METHODS FOR EFFICIENTLY CREATING DIGESTS OF DIGITAL DATA - Systems and methods efficiently process digests, hashes or other results by performing multiplicative functions in parallel with each other. In various embodiments, successive processing stages are provided, with each stage performing parallel multiplicative functions and also combining input terms to reduce the total number of terms that remain to be processed. By progressively combining the active terms into a smaller number of terms for subsequent processing, the time needed to process a result can be significantly reduced. | 05-05-2011 |
David King, Belmont, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090324605 | INTERFERON ALPHA ANTIBODIES AND THEIR USES - The present invention provides isolated anti-interferon alpha monoclonal antibodies, particularly human monoclonal antibodies, that inhibit the biological activity of multiple interferon (IFN) alpha subtypes but do not substantially inhibit the biological activity of IFN alpha 21 or the biological activity of either IFN beta or IFN omega. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the invention are also provided. The invention also provides methods for inhibiting the biological activity of IFN alpha using the antibodies of the invention, as well as methods of treating disease or disorders mediated by IFN alpha, such as autoimmune diseases, transplant rejection and graft versus host disease, by administering the antibodies of the invention. | 12-31-2009 |
| 20100104569 | HUMANIZED ANTIBODIES TO INTERFERON ALPHA RECEPTOR-1 (IFNAR-1) - Humanized monoclonal antibodies which bind to IFNAR-1, and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the humanized antibodies and therapeutic and diagnostic methods for using the humanized antibodies. | 04-29-2010 |
| 20100303817 | ANTIBODIES TO TREAT CANCER - Compositions and methods for the treatment of cancer, particularly melanoma, myeloma, small cell lung cancer, thymic lymphoma, T-cell lymphoma, B-cell lymphoma, osteosarcoma, and acute T-cell leukemia, are disclosed. Illustrative compositions include one or more anti-ganglioside antibodies and polynucleotides that encode such anti-ganglioside antibodies. These antibodies may be for example, hamster antibodies, chimeric human/hamster antibodies, or humanized antibodies. The disclosed compositions are useful, for example, in the treatment of cancer and can be used to induce apoptosis in a cancer cell. | 12-02-2010 |
| 20110086422 | HUMANIZED ANTIBODIES TO INTERFERON ALPHA RECEPTOR-1 (IFNAR-1) - Humanized monoclonal antibodies which bind to IFNAR-1, and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the humanized antibodies and therapeutic and diagnostic methods for using the humanized antibodies. | 04-14-2011 |
| 20110165158 | METHODS FOR THE THERAPY OF INFLAMMATORY BOWEL DISEASE USING A TYPE-1 INTERFERON ANTAGONIST - Compositions and methods for the therapy of Inflammatory Bowel Disease (IBD), including Celiac Disease, Crohn's Disease, and Ulcerative Colitis, are disclosed. Illustrative compositions comprise one or more anti-type 1 interferon antagonists, such as anti-type 1 interferon receptor antibody antagonists and fragments thereof, as well as polypeptides and small molecules that inhibit the interaction of type 1 interferon with its receptor (IFNAR). | 07-07-2011 |
David King, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080281079 | Bioactivation Of Particles - Particles are bioactivated by attaching bioactivation peptides to the particle surface. The bioactivation peptides are peptide-based compounds that impart one or more biologically important functions to the particles. Each bioactivation peptide includes a molecular or surface recognition part that binds with the surface of the particle and one or more functional parts. The surface recognition part includes an amino-end and a carboxy-end and is composed of one or more hydrophobic spacers and one or more binding clusters. The functional part(s) is attached to the surface recognition part at the amino-end and/or said carboxy-end. | 11-13-2008 |
| 20100262488 | POLICY-BASED MEDIA SYNDICATION AND MONETIZATION - Hosted content received from media hosts is used to generate a set of fingerprints representing the hosted content. The fingerprints representing the hosted content are compared to a set of fingerprints representing reference content submitted by content owners to generate one or more match metrics. Based on the match metrics, the media host may provide indication that they accept policy terms specified by the content owners, including revenue sharing terms. If the media host accepts the revenue sharing terms, the media host may provide advertising content to viewers in association with the hosted content matching the reference content. Funds received from providing advertising content are distributed to the media host and the content owner according to the revenue sharing terms. | 10-14-2010 |
| 20100263020 | POLICY-BASED VIDEO CONTENT SYNDICATION - An item of hosted content is received from a media host. A match metric representing an aspect of a match between the item of hosted content and an item of reference content, the item of reference content provided by a content owner having rights to the item of reference content. A policy associated with the item of reference content is identified responsive to the value to that represents the correspondence, the policy including terms of use for the hosted content. The policy is provided to the media host. | 10-14-2010 |
David King, Lansing, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20090239078 | Process and apparatus for diamond synthesis - The present invention relates to a microwave plasma deposition process and apparatus for producing diamond, preferably as single crystal diamond (SCD). The process and apparatus enables the production of multiple layers of the diamond by the use of an extending device to increase the length and the volume of a recess in a holder containing a SCD substrate as layers of diamond are deposited. The diamond is used for abrasives, cutting tools, gems, electronic substrates, heat sinks, electrochemical electrodes, windows for high power radiation and electron beams, and detectors. | 09-24-2009 |
| 20100034984 | Microwave plasma reactors - New and improved microwave plasma assisted reactors, for example chemical vapor deposition (MPCVD) reactors, are disclosed. The disclosed microwave plasma assisted reactors operate at pressures ranging from about 10 Torr to about 760 Torr. The disclosed microwave plasma assisted reactors include a movable lower sliding short and/or a reduced diameter conductive stage in a coaxial cavity of a plasma chamber. For a particular application, the lower sliding short position and/or the conductive stage diameter can be variably selected such that, relative to conventional reactors, the reactors can be tuned to operate over larger substrate areas, operate at higher pressures, and discharge absorbed power densities with increased diamond synthesis rates (carats per hour) and increased deposition uniformity. | 02-11-2010 |
David King, Allen, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090211845 | Lockable folding stairs - A two-piece locking folding stair is provided with a spring-like locking mechanism. The spring-like device, deployed one on of the two members, includes a protruding member which engages a notch on the other member when the stairs are in the full open, or locked position. When the stairs are opened, the device moves into a position which prevents the stairs from folding unintentionally. To unlock the assembly, the spring-like device is depressed thus releasing the protruding member from a corresponding notch, allowing the stairs to be folded to the closed position for stowing or transport. | 08-27-2009 |
David King, Derbyshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20090175673 | BINDERS FOR HOLDING LAMINAR OBJECTS - In the field of binders for laminar objects there is a need for a binder which is able to offer a distinctive and unusual appearance, | 07-09-2009 |
David King, Solana Beach, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110280891 | SITE-SPECIFIC ATTACHMENT OF DRUGS OR OTHER AGENTS TO ENGINEERED ANTIBODIES WITH C-TERMINAL EXTENSIONS - The present invention provides antibodies (e.g., IgG antibodies) having C-terminal cysteine-containing extensions that facilitate antibody conjugation to a partner molecule (e.g. a drug, toxin, marker molecule, protein, radioisotope, or other therapeutic agent). Methods of making, screening and selecting the antibodies of the invention are provided. | 11-17-2011 |