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David James Squirrell, Wiltshire GB

David James Squirrell, Wiltshire GB

Patent application numberDescriptionPublished
20080206751Method For Carrying Out A Multi-Step Reaction, Breakable Container For Storing Reagents And Method For Transferring Solid Reagent Using An Electrostatically Charged Wand - The application relates to a method of performing a multi-step reaction vessel (08-28-2008
20080233588Analytical Method and Kit - Analytical methods using RNA-containing probes for the detection or analysis of nucleic acid sequences is described. These probes are contacted with a sample suspected of containing the nucleic acid sequence and if they form duplexes, they are hydrolysed. This may be done, for example during an amplification reaction. AMP generated as a result of the hydrolysis is converted to ATP. The ATP may then be detected using bioluminescent reagents. Inclusion of modified adenosine in at least one probe means that the signal arising from one probe will give rise to a different and distinguishable bioluminescent signal thus enabling the use of for example an internal control in bioluminescently-reported nucleic acid tests.09-25-2008
20080274512Reagent Transfer Device - A device for transferring reagents in solid or liquid form from one place to another on an apparatus, said device comprising an upper portion, adapted to be held, and a lower portion adapted to hold reagents in solid or liquid form, in an available manner. For example, the reagents may be held within a cage structure or retained on an outer surface of the lower portion. Methods for using the device, as well as apparatus for use in conjunction with the device are also described and claimed.11-06-2008
20080290292Fluorescence-Based Detection Methods and Apparatus - In apparatus for detecting the emission of fluorescent radiation from a sample in response to excitation by two or more different radiation sources (11-27-2008
20080314855Liquid Dispensing Device with a Cap and a Diaphragm - A liquid dispensing device comprising a hollow body having an opening in a lower end thereof for receiving liquid, and an integrated cap member arranged to sealingly close the body, said cap member comprising a resilient diaphragm which is deformable in a downwards direction. The device is suitable for use in automated apparatus.12-25-2008
20100093069Reagent Delivery System - A delivery apparatus for selectively delivering one or more liquid reagents into a reaction or test chamber (04-15-2010
20100180980SAMPLE PROCESSOR - A sample delivery system comprising (i) a cartridge comprising a body section adapted to hold a sealed sample vessel so as to fix the position of a seal of the sample vessel in relation to the cartridge; and (ii) apparatus adapted to receive said cartridge, said apparatus being provided with an opening system for opening said sealed sample vessel contained within the cartridge.07-22-2010
20100190152Apparatus for Analysing A Sample and Assessing its Global Position - An apparatus for analysing a sample and assessing its global position, the apparatus comprising a portable sample analysing device and a global positioning device.07-29-2010
20100210010SAMPLE PROCESSOR - An integral magnet and heater device comprising a heating element with integral permanent magnet for use in a sample preparation or analysis apparatus. Also disclosed is a sheath adapted to cover a reusable processing component, such as a heater or sonicator, of an apparatus during use. Other associated aspects of the system are described and claimed.08-19-2010
20100297707REACTION VESSEL COMPRISING CONDUCTIVE LAYER AND INNER NON-METALLIC LAYER - A reaction vessel for conducting a chemical or biochemical reaction, such as a polymerase chain reaction wherein at least one wall of said vessel comprises a metallic layer and an inner non-metallic layer. Reaction systems comprising combinations of vessels of the invention and apparatus for heating them, as well as particular reactions vessels are also described and claimed.11-25-2010
20110045485ANALYTICAL METHOD AND KIT - RNA-containing probes and kits comprising RNA-containing probes for the detection and analysis of nucleic acid sequences are described. These probes are contacted with a sample suspected of containing the nucleic acid sequence and if they form duplexes, they are hydrolysed. This may be done, for example during an amplification reaction. AMP generated as a result of the hydrolysis is converted to ATP. The ATP may then be detected using bioluminescent reagents. Inclusion of modified adenosine in at least one probe means that the signal arising from one probe will give rise to a different and distinguishable bioluminescent signal thus enabling the use of for example an internal control in bioluminescently-reported nucleic acid tests.02-24-2011
20110065150REACTION VESSEL COMPRISING ELECTRICALLY CONDUCTING POLYMER AS A HEATING ELEMENT - A reaction vessel for conducting a chemical or biochemical reaction, such as a polymerase chain reaction wherein electrically conducting polymer is arranged to act as a heating element. The profile of the electrically conductive polymer differs in different regions of the vessel so as to control thermal gradients. The profile of the electrically conductive polymer may be arranged to either increase or reduce the thermal gradient. Reaction systems comprising combinations of vessels of the invention and apparatus for heating them, as well as particular reactions vessels are also described and claimed.03-17-2011

Patent applications by David James Squirrell, Wiltshire GB