| Patent application number | Description | Published |
|---|
| 20080261948 | Ligands for G-Protein Coupled Receptors - The invention provides compounds of general formulae I-IV or pharmaceutically acceptable salts thereof: | 10-23-2008 |
| 20090036486 | COMPOSITION - The invention relates to the use of 3-(2′,2′-dimethylpropanoylamino)-tetrahydropyridin-2-one for preparing a medicament intended to prevent or treat inflammatory disorders. | 02-05-2009 |
| 20090075872 | METHODS AND MEANS - This invention relates to methods and means for the stimulation of phagocytosis and in particular to the phagocytosis of apoptotic cells, and discloses a role for the protein product of the apoE gene (apolipoproteinE) as a regular of apoptotic cell clearance. ApoE mimetics and other compounds which stimulate the clearance of apoptotic cells may be useful in the treatment of a range of disorders. One aspect of the invention provides a method of identifying and/or obtaining a compound for the treatment of a condition associated with decreased endogenous apoE activity in an individual comprising: determining the ingestion of apoptic cells by a macrophage in the presence of a test compound. An increase in apoptic cell ingestion in the presence relative to the absence of test compound may be indicative that the compound may be useful in the treatment of a condition associated with decreased endogenous apoE activity. | 03-19-2009 |
| 20090203739 | Anti-Inflammatory Agents - The invention provides compounds, pharmaceutical compositions and uses of compounds of general formula (I) or a pharmaceutically acceptable salt thereof, for the preparation of a medicament intended to treat an inflammatory disorder; wherein z X is 1, 2 or 4; X is —CO—Y | 08-13-2009 |
| 20090221713 | APOE MIMETIC AGENTS - The invention provides low molecular weight apoE mimetic agents suitable for preparing a medicament to treat autoimmune, inflammatory or neurodegenerative disease, (X) | 09-03-2009 |
| 20100016286 | Anti-Inflammatory Agents - The invention provides compounds, pharmaceutical compositions and uses of compounds and salts thereof of general formula (I), for the preparation of a medicament for treatment of an inflammatory disorder, but excluding (S)-3-(r-methylcyclohexyl-carbonylamino)-caprolactam: wherein z is 1, 2, 3 or 4; A is —CO— or —SO2-; Q is linear or branched alkyl, alkenyl, alkynyl, alkoxy, oxyalkyl, aminoalkyl, alkylamino, alkylaminoalkyl, haloalkyl, aryl or substituted aryl; T | 01-21-2010 |
| 20100099642 | TGF-BETA STIMULANT AND FURTHER AGENT TO REDUCE SIDE EFFECTS - The invention relates to the use of TGF-beta stimulating agents, and in particular members of the triphenylethylene class of pharmaceutical agents, for the prevention, prophylaxis, treatment or amelioration of symptoms of cardiovascular disease, autoimmune diseases or neurodegeneration. In particular, improved compositions consisting of triphenylethylene agents combined with one or more additional active pharmaceutical agents in order to mitigate against side-effects of the triphenylethylene are described and claimed. | 04-22-2010 |
| 20100113518 | METHODS OF USING ANTI-INFLAMMATORY COMPOUNDS - The invention relates to the use of 3-(2′,2′-dimethylpropanoylamino)-tetrahydropyridin-2-one for preparing a medicament intended to prevent or treat inflammatory disorders. | 05-06-2010 |
| 20110003792 | ANTI-INFLAMMATORY AGENTS - The invention provides compounds, pharmaceutical compositions and uses of compounds and salts thereof of general formula (I), for the preparation of a medicament for treatment of an inflammatory disorder, | 01-06-2011 |
