Datta

Datta Arunabha, Dehradun IN

Patent application number	Description	Published
20080234524	Process for the liquid phase selective hydroxylation of benzene - The present invention provides an improved process for the liquid phase selective hydroxylation of benzene. The process provides a direct single step selective liquid phase hydroxylation of benzene to phenol using environment friendly green oxidant, hydrogen peroxide, and vanadyl pyrophosphate as the catalyst under mild reaction conditions. The process provides benzene conversion of 30-70% and selectivity for phenol of up to 100%.	09-25-2008

Patent application number	Description	Published
20110124909	NOVEL PROCESS - The present invention relates to a novel process of preparing an enantiomerically enriched γ-amino acid, such as enantiomerically enriched (S)-pregabalin.	05-26-2011

Patent application number	Description	Published
20120028316	ENZYMATIC PROCESS FOR THE PREPARATION OF (S)-5-(4-FLUORO-PHENYL)-5-HYDROXY- 1MORPHOLIN-4-YL-PENTAN-1-ONE, AN INTERMEDIATE OF EZETIMIBE AND FURTHER CONVERSION TO EZETIMIBE - The present invention provides an enzymatic process for the preparation of (S)-5-(4-Fluoro-phenyl)-5-hydroxy-1morpholin-4-yl-pentan-1-one by the reduction of 1-(4-Fluoro-phenyl)-5-morpholin-4-yl-pentane-1,5-dione by using a suitable enzyme or by the resolution of (R,S)-5-(4-Fluoro-phenyl)-5-hydroxy-1morpholin-4-yl-pentan-1-one by using an enzyme. The present invention also provides process for the preparation of Ezetimibe comprising the steps of a) protecting the compound (S)-5-(4-Fluoro-phenyl)-5-hydroxy-1morpholin-4-yl-pentan-1-one with hydroxy protecting group b) hydrolyzing the obtained compound c) condensing with a chiral auxiliary d) reacting with an protected imine compound e) converting to alkyl ester f) cyclizing and g) deprotecting to obtain Ezetimibe.	02-02-2012