| Patent application number | Description | Published |
|---|
| 20090081293 | SUSTAINED RELEASE OF APO A-I MIMETIC PEPTIDES AND METHODS OF TREATMENT - A method including advancing a delivery device through a lumen of a blood vessel to a particular region in the blood vessel; and introducing a composition including a sustained-release carrier and an apolipoprotein A-I (apo A-I) synthetic mimetic peptide into a wall of the blood vessel at the particular region or a perivascular site, wherein the peptide has a property that renders the peptide effective in reverse cholesterol transport. A composition including an apolipoprotein A-I (apo A-I) synthetic peptide, or combination of an apo A-I synthetic mimetic peptide and an Acyl CoA cholesterol: acyltransferase (ACAT) inhibitor in a form suitable for delivery into a blood vessel, the peptide including an amino acid sequence in an order reverse to an order of various apo A-I mimetic peptides, or endogenous apo A-I analogs, or a chimera of helix 1 and helix 9 of endogenous apo A-I. | 03-26-2009 |
| 20090081299 | SUSTAINED RELEASE OF APO A-I MIMETIC PEPTIDES AND METHODS OF TREATMENT - A method including advancing a delivery device through a lumen of a blood vessel to a particular region in the blood vessel; and introducing a composition including a sustained-release carrier and an apolipoprotein A-I (apo A-I) synthetic mimetic peptide into a wall of the blood vessel at the particular region or a perivascular site, wherein the peptide has a property that renders the peptide effective in reverse cholesterol transport. A composition including an apolipoprotein A-I (apo A-I) synthetic peptide, or combination of an apo A-I synthetic mimetic peptide and an Acyl CoA cholesterol: acyltransferase (ACAT) inhibitor in a form suitable for delivery into a blood vessel, the peptide including an amino acid sequence in an order reverse to an order of various apo A-I mimetic peptides, or endogenous apo A-I analogs, or a chimera of helix 1 and helix 9 of endogenous apo A-I. | 03-26-2009 |
| 20090087865 | Monoclonal Antibodies to Tacrolimus and Immunoassays Methods for Tacrolimus | 04-02-2009 |
| 20090148491 | Dual-Targeted Drug Carriers - The present invention relates to implantable medical devices containing surface-treated, dual-targeted drug carriers for treating vascular diseases. | 06-11-2009 |
| 20100100169 | Medical devices containing biobeneficial particles - A method of modifying a medical device such as a stent with nano-constructs is disclosed. The method comprises applying a first fluid to the stent; immersing the stent being wet from the first fluid into a second fluid having a suspension of nano-constructs; and removing the stent from the second fluid and allowing the first and second fluid to be removed such that the nano-constructs are carried by the stent for in vivo application of the constructs to a target location of a mammalian subject. The nano-constructs can be attached to the surface of the stent, can be attached to a surface of the coating of the stent, can be embedded into the stent, or can be embedded into the coating. | 04-22-2010 |
| 20100244293 | Method For The Manufacture Of Stable, Nano-Sized Particles - The current invention relates to methods of making nano-particles of a material with a narrow polydispersity. The particle materials are active agents, organic compounds, polymers, and combinations thereof. | 09-30-2010 |
| 20100330147 | Drug Delivery Compositions Including Nanoshells For Triggered Drug Release - The current invention is directed to compositions comprising a plurality of particles including nanoshells or a medical device with a coating including nanoshells allowing for triggered drug release. Methods of treatment with such compositions are also included. | 12-30-2010 |
| 20100331819 | Drug Delivery System and Method of Treatment of Vascular Diseases Using Photodynamic Therapy - This invention relates to photodynamic therapy (PDT), more specifically PDT for atherosclerotic plaque via delivering PDT-loaded nanoparticles such as liposomes, polymersomes, micelles and polymeric nanoparticles into the diseased vascular tissue. This invention provides method and formulations for delivering multiple drugs and delivering drugs to specific targeted site. | 12-30-2010 |
| 20110066225 | Bioabsorbable Stent With Time Dependent Structure And Properties And Regio-Selective Degradation - A bioabsorbable polymeric stent with time dependent structure and properties and methods of treating a diseased blood vessel with the bioabsorable polymeric stent are disclosed. The structure and properties of the stent change with time and allow the vessel to be restored to a natural unstented state. The bioabsorbable stent loses mechanical integrity in a controlled manner due to modification of selected structural elements. | 03-17-2011 |
