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Daqing Che

Daqing Che, Brantford CA

Patent application numberDescriptionPublished
20080312433Novel process to Form-I of olanzapine - A process for obtaining crystalline Form-I olanzapine comprising the following: 12-18-2008
20080319189Processes for the synthesis of olanzapine - There is provided a process for the preparation of olanzapine comprising: 12-25-2008
20090023955Novel process for the preparation of sertraline hydrochloride form II - The present invention relates to novel processes to produce sertraline hydrochloride Form II comprising the steps of forming a solution of sertraline hydrochloride in a polar organic solvent and adding this solution to a less polar organic solvent.01-22-2009
20090082558Amorphous form of rifaximin and processes for its preparation - A stable amorphous form of rifaximin is disclosed. This form is chemically and polymorphically stable on storage and can be prepared by dissolving rifaximin in a solvent to form a solution, which is precipitated by adding an anti-solvent and isolating of the precipitated amorphous rifaximin as an end product.03-26-2009
20090131683Process for the preparation of atorvastatin and intermediates - A process is provided for preparing (R)-5-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-5-hydroxy-3-oxo-1-heptanoic acid, R-substituted ester 9 comprising: 05-21-2009
20110065931ATORVASTATIN CALCIUM PROPYLENE GLYCOL SOLVATES - Atorvastatin calcium propylene glycol solvates and processes to prepare these novel solvates which are particularly useful and suitable for pharmaceutical applications.03-17-2011

Patent applications by Daqing Che, Brantford CA

Daqing Che, Brantford CN

Patent application numberDescriptionPublished
20100324298Novel Process for the Preparation of Esomeprazole and Salts Thereof - A novel process for the preparation of omeprazole and its enantiomers, such as esomeprazole, as well as the preparation of related 2-(2-pyridinylmethyl-sulphinyl)-1H-benzimidazoles, including pantoprazole, lansoprazole and rabeprazole, as recemates or single enantiomers, and their alkali or alkaline salts has been developed. The novel process involves the surprising discovery that protection of the free-base benzimidazole sulfoxide (e.g. omeprazole or esomeprazole), by reaction with an alkyl, aryl or aralkyl chloroformate following oxidation of the corresponding sulfide, eliminates the need for its direct isolation. Subsequent removal of the protecting group with a solution of alkali or alkaline earth alkoxide in a C1-C4 alcohol directly provides the corresponding salt. By eliminating the need to handle the free-base benzimidazole sulfoxide, this advantageous procedure provides increased chemical yields over processes described in the art.12-23-2010

Daqing Che, Taizhou City CN

Patent application numberDescriptionPublished
20090247749SALT FORM AND COCRYSTALS OF ADEFOVIR DIPIVOXIL AND PROCESSES FOR PREPARATION THEREOF - The present invention is directed to novel crystalline forms of adefovir dipivoxil and salts thereof.10-01-2009