| Patent application number | Description | Published |
|---|
| 20080319427 | COMPUTER GUIDED PATTERNED LASER TRABECULOPLASTY - A system and method of performing therapy on target eye tissue. A light source produces a beam of light, and a scanning device deflects the light beam to produce an pattern of the light beam. An ophthalmic lens assembly includes a mirror for reflecting the light beam pattern onto the target eye tissue. The mirror is rotatable to angularly align the light beam pattern to the target tissue. Control electronics control the scanning device to apply the light beam pattern onto the reflective optical element at first and second angular orientations separated by a predetermined angle RA. The predetermined angle RA is set such that light beam patterns applied to the target tissue at the first and second angular orientations, which are also angularly aligned to the target tissue through rotation of the mirror, automatically are adjacently abutting to each other on the target tissue. | 12-25-2008 |
| 20100103103 | Method And Device for Input Of Information Using Visible Touch Sensors - A device and method for manual input of information into computing device using a camera and visible touch sensors. An image of a virtual input device is displayed on a screen, and the positions of the visible touch sensors, recorded by the video camera, are overlaid on the image of the virtual input device, thus allowing the user to see the placement of the touch sensors relative to the keys or buttons on the virtual input device. The touch sensors change their appearance upon contact with a surface, and the camera records their position at the moment of change. This way information about the position of intended touch is recorded. Touch sensors can be binary (ON-OFF) or may have a graded response reflecting the extent of displacement or pressure of the touch sensor relative to the surface of contact. | 04-29-2010 |
| 20100168724 | Method and apparatus for photothermal therapy with adjustable spatial and/or temporal beam profile - The safe therapeutic window for laser medicine (a ratio of the threshold power for detrimental outcome to that of a desired outcome) tends to decrease as pulse length decreases. This problem is addressed by use of beam shapes and/or pulse shapes that improve temperature uniformity in the treated tissue. A beam shape with an adjustable on-axis intensity minimum improves spatial temperature uniformity in treated tissue. A pulse shape with a relatively intense early part (to set the temperature rise), followed by a less intense late part having decreasing intensity with time (to maintain a constant or nearly constant temperature rise) improves temporal temperature uniformity in the treated tissue. A therapeutic window (TW) of at least 3 is often required to provide a sufficient safety margin in practice. In one experiment, it was demonstrated that the minimum pulse length to provide a TW of 3 could be decreased from 20 ms to 10 ms following these principles. | 07-01-2010 |
| 20100191226 | Method Of Patterned Plasma-Mediated Laser Trephination Of The Lens Capsule And Three Dimensional Phaco-Segmentation - System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist. | 07-29-2010 |
| 20100198216 | Electro-thermotherapy of tissue using penetrating microelectrode array - Electrosurgical therapy is provided with an electrode array configured to ablate tissue during insertion of the electrode array into tissue being treated. Once the electrode array is fully inserted, deep heating of the treated tissue can be performed by applying an additional waveform to the tissue with the electrode array. Optionally, the electrical waveform can be varied continuously during insertion of the electrode array to control the extent of coagulation at the side walls and at the bottom of the channels produced by tissue ablation. | 08-05-2010 |
| 20100227408 | Method and apparatus for avalanche-mediated transfer of agents into cells - The present invention provides a method and apparatus for transferring an agent into a cell. The method includes the steps of providing an agent outside of a cell and generating a vapor bubble and a plasma discharge between an avalanche electrode and a conductive fluid surrounding the cell. The vapor bubble and plasma discharge generate a mechanical stress wave and an electric field, respectively. The combination of this mechanical stress wave and electric field results in permeabilization of the cell, which in turn results in transfer of the agent into the cell. | 09-09-2010 |
| 20100249760 | Patterned Laser Treatment - Patterned laser treatment of the retina is provided. A visible alignment pattern having at least two separated spots is projected onto the retina. By triggering a laser subsystem, doses of laser energy are automatically provided to at least two treatment locations coincident with the alignment spots. All of the doses of laser energy may be delivered in less than about 1 second, which is a typical eye fixation time. A scanner can be used to sequentially move an alignment beam from spot to spot on the retina and to move a treatment laser beam from location to location on the retina. | 09-30-2010 |
| 20110178511 | METHOD AND APPARATUS FOR PATTERNED PLASMA-MEDIATED LASER TREPHINATION OF THE LENS CAPSULE AND THREE DIMENSIONAL PHACO-SEGMENTATION - System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist. | 07-21-2011 |
| 20110178512 | METHOD AND APPARATUS FOR PATTERNED PLASMA-MEDIATED LASER TREPHINATION OF THE LENS CAPSULE AND THREE DIMENSIONAL PHACO-SEGMENTATION - System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist. | 07-21-2011 |
| 20110229952 | METHOD AND APPARATUS FOR AVALANCHE-MEDIATED TRANSFER OF AGENTS INTO CELLS - The present invention provides a method and apparatus for transferring an agent into a cell. The method includes the steps of providing an agent outside of a cell and generating a vapor bubble and a plasma discharge between an avalanche electrode and a conductive fluid surrounding the cell. The vapor bubble and plasma discharge generate a mechanical stress wave and an electric field, respectively. The combination of this mechanical stress wave and electric field results in permeabilization of the cell, which in turn results in transfer of the agent into the cell. | 09-22-2011 |
