| Patent application number | Description | Published |
|---|
| 20090047291 | MODULATORS OF HEPATOCYTE GROWTH FACTOR ACTIVATOR - The invention provides methods and compositions for modulating hepatocyte growth factor activator function. | 02-19-2009 |
| 20090075317 | METHODS AND COMPOSITIONS FOR MODULATING HEPATOCYTE GROWTH FACTOR ACTIVATION - The invention provides methods and compositions for modulating hepsin activity and the HGF/c-met signaling pathway, in particular by regulating pro-HGF activation by hepsin. | 03-19-2009 |
| 20100021474 | METHODS AND COMPOSITIONS FOR TARGETING HEPSIN - Anti-HEPSIN monoclonal antibodies, and methods for using the antibodies, are provided. | 01-28-2010 |
| 20100040634 | METHODS AND COMPOSITIONS FOR MODULATING HGF/MET - The invention provides methods and compositions for modulating the HGF/c-met signaling pathway, in particular by regulating binding of HGF β chain to c-met. | 02-18-2010 |
| 20100061996 | METHODS AND COMPOSITIONS FOR MODULATING HEPSIN ACTIVATION OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR - The invention provides methods and compositions for modulating hepsin activity and the uPA/plasmin pathway, in particular by regulating pro-uPA activation by hepsin. | 03-11-2010 |
| 20100113350 | METHODS AND COMPOSITIONS FOR MODULATING PROSTASIN - The invention provides methods and compositions related to modulating prostasin. | 05-06-2010 |
| 20100209956 | METHODS AND COMPOSITIONS FOR MODULATING HEPATOCYTE GROWTH FACTOR ACTIVATION - The invention provides methods and compositions for modulating hepsin activity and the HGF/c-met signaling pathway, in particular by regulating pro-HGF activation by hepsin. | 08-19-2010 |
| 20100210826 | HGF BETA CHAIN VARIANTS - The invention provides HGF/Met modulators comprising HGF having mutations in regions that affect HGF function, and antagonists that target said regions. The invention further provides methods of identifying, making and using these modulators. | 08-19-2010 |
| 20100277473 | CRYSTAL STRUCTURE OF HEPATOCYTE GROWTH FACTOR ACTIVATOR COMPLEXED WITH KUNITZ DOMAIN INHIBITOR - The present disclosure provides crystals of and structural coordinates of Hepatocyte growth factor activator with and without bound pseudo-substrate or inhibitor. In a specific embodiment, a crystal structure of activated HGFA complexed with a Kunitz domain inhibitor is provided. The crystals and crystal structures are useful, for example, in the design and synthesis of inhibitors of HGFA. | 11-04-2010 |
| 20110098449 | MODULATORS OF HEPATOCYTE GROWTH FACTOR ACTIVATOR - The invention provides methods and compositions for modulating hepatocyte growth factor activator function. | 04-28-2011 |
