| Patent application number | Description | Published |
|---|
| 20080286321 | Polymer No Donor Predrug Nanofiber Coating for Medical Devices and Therapy - The present invention relates to nanofibers that produce therapeutic amounts of nitric oxide after a delay period, which allows time to install or implant the device into a patient. The nitric oxide release is thus localized to the area of the organism where NO dosing is indicated. The delay time is achieved by cospinning the NO-producing fiber with a fiber that tends to sequester the former's NO-producing functional groups. Fibers of the present invention may be incorporated into medical devices such as stents or other implantable medical devices to prevent the formation of adhesions or scarring in the area of the implant. | 11-20-2008 |
| 20090069449 | ETHAMBUTOL BASED NITRIC OXIDE DONORS - The present invention relates generally to nitric oxide releasing pharmaceutical compounds. More particularly, the present invention relates to pharmaceutical compositions that release nitric oxide under physiological conditions. In one embodiment, the present invention relates to new chemical compounds—diazeniumdiolates nitric oxide donors—that are based on ethambutol possessing physiological and biomedical activity. | 03-12-2009 |
| 20090075354 | NANOFIBER STRUCTURES FOR SUPPORTING BIOLOGICAL MATERIALS - The present invention relates generally to nanofiber structures designed to support, entrap, entangle, preserve, and/or retain one or more biological materials. More specifically, the present invention relates to nanofiber matrix structures made from at least two different types of nanofibers that are designed to support, entrap, entangle, preserve, and/or retain one or more biological materials. | 03-19-2009 |
| 20090093585 | ABSORBENT NON-WOVEN FIBROUS MATS AND PROCESS FOR PREPARING SAME - The present invention relates to liquid entrapping devices (e.g., absorbent non-woven fibrous mats) and to a process for preparing such devices. More particularly, the present invention relates to mechanically strong absorbent materials made from such liquid entrapping devices (e.g., non-woven fibrous mats) and to a method for preparing same. In one embodiment, a liquid entrapping device of the present invention comprises at least one hydrophilic elastomeric fibrous component (HEFC) and at least one wetting agent component. In another embodiment, a liquid entrapping device of the present invention comprise at least one hydrophilic elastomeric fibrous component (HEFC), at least one absorbent component, and at least one wetting agent component. In one instance, the wetting agent component of the present invention is contained on and/or within the fibers and/or nanofibers that form the liquid entrapping device (e.g., a non-woven fibrous mat) of the present invention. | 04-09-2009 |
| 20090136410 | Stabilization and ionic triggering of nitric oxide release - Provided is a method for producing nitric oxide that employs an ion exchange resin. Also provided is a method for producing nitric oxide that combines a salt with a gel or cream. A method is provided for producing nitric oxide that combines a Ph adjuster with a diazeniumdiolate-containing compound or composition. | 05-28-2009 |
| 20090214624 | TOPICAL NITRIC OXIDE DONOR DEVICES AND METHODS FOR THEIR THERAPEUTIC USE - The present invention is related to topical nitric oxide delivery systems, and to using the same for mitigating or remediating various disease states The present invention is also related to using topical nitric oxide delivery systems for enhancing blood flow. | 08-27-2009 |
| 20090220378 | INDICATOR DEVICE HAVING AN ACTIVE AGENT ENCAPSULATED IN AN ELECTROSPUN NANOFIBER - An indicator device for determining the efficacy of an antimicrobial treatment process. The indicator device includes an active agent encapsulated in an encapsulation component. The encapsulation components preferably takes the form of an electrospun nanofiber including a polymer. | 09-03-2009 |
| 20090324680 | NANOFIBER-REINFORCED COMPOSITION FOR APPLICATION TO SURGICAL WOUNDS - A nanofiber-reinforced composition suited to applying to a wound site in a human body includes a carrier liquid and nanofibers dispersed therein. The viscosity of the composition is such that it is able to be applied through a tube yet adhere proximate the wound site to provide a barrier layer which assists in healing of the wound by spacing it from neighboring organs. | 12-31-2009 |
| 20110028878 | NON-WOVEN FIBER ASSEMBLIES - In one embodiment, the present invention relates to a non-woven fiber assembly comprising one or more fibers wherein each fiber contains: a hydrophilic component; and an elastomeric component, and wherein the non-woven fiber assembly further comprises an adhesive component. In still another embodiment, the present invention relates to a non-woven fiber assembly comprising one or more fibers wherein each fiber contains: a hydrophilic component; an elastomeric component; and an adhesive component, wherein the hydrophilic component, the elastomeric component and the adhesive component are all contained within each fiber. Also disclosed is a method of making the afore-mentioned non-woven fiber assemblies. Additionally, a medical dressing made from the non-woven fiber assemblies of the present invention is disclosed. | 02-03-2011 |
| 20110033437 | Debridement Method Using Topical Nitric Oxide Donor Devices and Compositions - The present invention relates to methods for removal of dead tissue from wounds or skin using topical nitric oxide donor devices and/or compositions. In one embodiment, the present invention relates to a transdermal patch device that is designed to deliver nitric oxide. In another embodiment, the present invention relates to one or more devices and/or compositions that are designed to deliver nitric oxide and optionally one or more other compounds, where such devices/compositions include, without limitation, bandages, layered bandages, adhesive bandages, transdermal patches, creams, ointments, or a any combination of two or more thereof. | 02-10-2011 |
